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Discovery of Selective Cannabinoid CB 2 Receptor Agonists by High-Throughput Screening.

Autor: Ogawa LM; 1 Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA., Burford NT; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Liao YH; 3 Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, USA., Scott CE; 3 Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, USA., Hine AM; 3 Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, USA., Dowling C; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Chin J; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Power M; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Hunnicutt EJ Jr; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Emerick VL; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Banks M; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Zhang L; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Gerritz SW; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Alt A; 2 Bristol-Myers Squibb, Research and Development, Wallingford, CT, USA., Kendall DA; 3 Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, USA.

Publikováno v: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2018 Apr; Vol. 23 (4), pp. 375-383. Date of Electronic Publication: 2017 Dec 19.

An alternative helix in the 26S rRNA promotes excision and integration of the Tetrahymena intervening sequence.

Autor: Woodson SA; Department of Chemistry and Biochemistry, University of Maryland, College Park 20740-2021., Emerick VL

Publikováno v: Molecular and cellular biology [Mol Cell Biol] 1993 Feb; Vol. 13 (2), pp. 1137-45.