Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Emer R. McGrath"'
Autor:
Martin D. Mulligan, Robert Murphy, Catriona Reddin, Conor Judge, John Ferguson, Alberto Alvarez-Iglesias, Emer R. McGrath, Martin J. O’Donnell
Publikováno v:
EClinicalMedicine, Vol 60, Iss , Pp 102012- (2023)
Summary: Background: Quantifying the proportion of dementia attributable to highly prevalent modifiable risk factors, such as hypertension, is important in informing effective dementia prevention strategies. We aim to quantify the population attribut
Externí odkaz:
https://doaj.org/article/d0bdc95c7cb54b469e51779b0781ce6b
Autor:
Emer R. McGrath, Jayandra J. Himali, Vanessa Xanthakis, Meredith S. Duncan, Jean E. Schaffer, Daniel S. Ory, Linda R. Peterson, Charles DeCarli, Matthew P. Pase, Claudia L. Satizabal, Ramachandran S. Vasan, Alexa S. Beiser, Sudha Seshadri
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 2, Pp 160-168 (2020)
Abstract Background We determined the association between ratios of plasma ceramide species of differing fatty‐acyl chain lengths and incident dementia and Alzheimer’s disease (AD) dementia in a large, community‐based sample. Methods We measure
Externí odkaz:
https://doaj.org/article/0ee89036409f4d04b80fe977f60bc8ca
Autor:
Emer R. McGrath, Jayandra J. Himali, Daniel Levy, Sarah C. Conner, Charles S. DeCarli, Matthew P. Pase, Paul Courchesne, Claudia L. Satizabal, Ramachandran S. Vasan, Alexa S. Beiser, Sudha Seshadri
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 9, Pp 1659-1670 (2019)
Abstract Objective To determine the association between plasma insulin‐like growth factor binding protein 2 (IGFBP‐2) and cognitive outcomes. Methods We measured plasma IGFBP‐2 levels in 1596 (53% women, mean age 68.7 [SD 5.7] years) dementia
Externí odkaz:
https://doaj.org/article/ecfae2091cc54802a51fff138e30c451
Autor:
Honghuang Lin, Jayandra J. Himali, Claudia L. Satizabal, Alexa S. Beiser, Daniel Levy, Emelia J. Benjamin, Mitzi M. Gonzales, Saptaparni Ghosh, Ramachandran S. Vasan, Sudha Seshadri, Emer R. McGrath
Publikováno v:
Cells, Vol 11, Iss 9, p 1506 (2022)
Blood biomarkers for dementia have the potential to identify preclinical disease and improve participant selection for clinical trials. Machine learning is an efficient analytical strategy to simultaneously identify multiple candidate biomarkers for
Externí odkaz:
https://doaj.org/article/090e45a2fc2646968dd0e3a689f57f53
Autor:
Emer R. McGrath, Jayandra J. Himali, Daniel Levy, Sarah C. Conner, Charles DeCarli, Matthew P. Pase, Toshiharu Ninomiya, Tomoyuki Ohara, Paul Courchesne, Claudia L. Satizabal, Ramachandran S. Vasan, Alexa S. Beiser, Sudha Seshadri
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 19 (2020)
Background GDF15 (growth differentiation factor 15) and NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) may offer promise as biomarkers for cognitive outcomes, including dementia. We determined the association of these biomarkers with c
Externí odkaz:
https://doaj.org/article/af8ae7f41abc4647a1432a7d44464840
Publikováno v:
Neurology. 100:879-883
Cerebral venous sinus thrombosis (CVST) is uncommon. Risk factors include inherited and acquired factors. Rapid diagnosis and treatment is essential and can help prevent complications, which can include seizures and visual disturbance. A 25-year-old
Autor:
Emer R, McGrath, Alexa S, Beiser, Adrienne, O'Donnell, Qiong, Yang, Saptaparni, Ghosh, Mitzi M, Gonzales, Jayandra J, Himali, Claudia L, Satizabal, Keith A, Johnson, Russell P, Tracy, Sudha, Seshadri
Publikováno v:
Journal of Alzheimer's Disease. 87:1517-1526
Background: Plasma phosphorylated-tau181 (p-tau181) is a promising biomarker for Alzheimer’s disease (AD) and may offer utility for predicting preclinical disease. Objective: To evaluate the prospective association between plasma p-tau181 and amylo
Autor:
Emer R. McGrath, Alexa S. Beiser, Adrienne O'Donnell, Jayandra J. Himali, Matthew P. Pase, Claudia L. Satizabal, Sudha Seshadri
Publikováno v:
Neurology
Background and ObjectivesThe association between vascular risk factors and dementia varies with age, making generalizability of dementia risk prediction rules to individuals of different ages challenging. We determined the most important vascular ris
Autor:
Emer R McGrath, Matthew R Scott, Rachel Buckley, Claudia L Satizabal, Charles S. DeCarli, Shalender Bhasin, Ramachandran S Vasan, Joanne M Murabito, Alexa S Beiser, Sudha Seshadri
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Emer R. McGrath, Jayandra J. Himali, Daniel Levy, Qiong Yang, Charles S. DeCarli, Paul Courchesne, Claudia L. Satizabal, Rebecca Finney, Ramachandran S. Vasan, Alexa S. Beiser, Sudha Seshadri
Publikováno v:
Journal of Alzheimer's Disease. 85:1657-1666
Background: Epidermal growth factor containing fibulin extracellular matrix protein-1 (EFEMP1) has been associated with increased white matter hyperintensities (WMH) burden and disorders of premature aging and may have a shared pathophysiological rol