Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emelyne Teo"'
Autor:
Emelyne Teo, Soon Yew John Lim, Sheng Fong, Anis Larbi, Graham D. Wright, Nicholas Tolwinski, Jan Gruber
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss , Pp 11-21 (2020)
Alzheimer’s disease (AD), characterized by memory loss and cognitive decline, is one of the diseases with the highest attrition rate in drug development. As with other neurodegenerative diseases, AD manifests on several scales (molecular, cellular
Externí odkaz:
https://doaj.org/article/2c7e77291e524e2eb5996ee15a6c1919
Publikováno v:
Bio-Protocol, Vol 10, Iss 23 (2020)
Alzheimer’s Disease (AD) has long been associated with accumulation of extracellular amyloid plaques (Aβ) originating from the Amyloid Precursor Protein. Plaques have, however, been discovered in healthy individuals and not all AD brains show plaq
Externí odkaz:
https://doaj.org/article/d7d4e6502ea145e5a652f1a04c47d4ee
Autor:
Chu Hsien Lim, Prameet Kaur, Emelyne Teo, Vanessa Yuk Man Lam, Fangchen Zhu, Caroline Kibat, Jan Gruber, Ajay S Mathuru, Nicholas S Tolwinski
Publikováno v:
eLife, Vol 9 (2020)
The brains of Alzheimer’s disease patients show a decrease in brain mass and a preponderance of extracellular Amyloid-β plaques. These plaques are formed by aggregation of polypeptides that are derived from the Amyloid Precursor Protein (APP). Amy
Externí odkaz:
https://doaj.org/article/92b095df61944eb6979288e58c478d4a
Autor:
Emelyne Teo, Sudharshan Ravi, Diogo Barardo, Hyung-Seok Kim, Sheng Fong, Amaury Cazenave-Gassiot, Tsze Yin Tan, Jianhong Ching, Jean-Paul Kovalik, Markus R Wenk, Rudiyanto Gunawan, Philip K Moore, Barry Halliwell, Nicholas Tolwinski, Jan Gruber
Publikováno v:
eLife, Vol 8 (2019)
Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the elderly worldwide. Mitochondrial dysfunction has been proposed as a key event in the etiology of AD. We have previously modeled amyloid-beta (Aβ)-induced mitochond
Externí odkaz:
https://doaj.org/article/eb3eb4a1028f48789394b89e79678ebd
Autor:
Sheng Fong, Emelyne Teo, Soon Yew John Lim, Jan Gruber, Anis Larbi, Nicholas S. Tolwinski, Graham D. Wright
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss, Pp 11-21 (2020)
Alzheimer’s disease (AD), characterized by memory loss and cognitive decline, is one of the diseases with the highest attrition rate in drug development. As with other neurodegenerative diseases, AD manifests on several scales (molecular, cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871f95cad79e4f8d64331e15bfa75e99
https://doi.org/10.1016/j.tma.2019.12.002
https://doi.org/10.1016/j.tma.2019.12.002
Publikováno v:
GeroScience
Alzheimer’s disease (AD) is the most common cause of dementia worldwide. AD is a multifactorial disease with simultaneous occurrence of several connected pathological processes including mitochondrial dysfunction and impaired proteostasis. Most of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf57e96bb78fddf7f840629da579bfd
https://europepmc.org/articles/PMC7286995/
https://europepmc.org/articles/PMC7286995/
Autor:
Nicholas S. Tolwinski, Chu Hsien Lim, Prameet Kaur, Jan Gruber, Caroline Kibat, Vanessa Yuk Man Lam, Fangchen Zhu, Emelyne Teo, Ajay S. Mathuru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998e4e8a53f1867fd07ff348635270a8
https://doi.org/10.7554/elife.52589.sa2
https://doi.org/10.7554/elife.52589.sa2
Autor:
Caroline Kibat, Jan Gruber, Nicholas S. Tolwinski, Ajay S. Mathuru, Prameet Kaur, Emelyne Teo
Publikováno v:
BIO-PROTOCOL. 10
Alzheimer's Disease (AD) has long been associated with accumulation of extracellular amyloid plaques (Aβ) originating from the Amyloid Precursor Protein. Plaques have, however, been discovered in healthy individuals and not all AD brains show plaque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa2bad71fea84800053900f232e7c2e8
https://doi.org/10.21769/bioprotoc.3856
https://doi.org/10.21769/bioprotoc.3856
Autor:
Jan Gruber, Sudharshan Ravi, Markus R. Wenk, Jean-Paul Kovalik, Philip K. Moore, Hyung-Seok Kim, Nicholas S. Tolwinski, Amaury Cazenave-Gassiot, Jianhong Ching, Diogo Barardo, Sheng Fong, Rudiyanto Gunawan, Barry Halliwell, Emelyne Teo, Tsze Yin Tan
Publikováno v:
eLife, 8
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the elderly worldwide. Mitochondrial dysfunction has been proposed as a key event in the etiology of AD. We have previously modeled amyloid-beta (Aβ)-induced mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e4143554be35044c5f61d6f204cad5
https://doi.org/10.7554/elife.50069
https://doi.org/10.7554/elife.50069
Autor:
Jean-Paul Kovalik, Sheng Fong, Emelyne Teo, Jan Gruber, Rudiyanto Gunawan, Hyung-Seok Kim, Sudharshan Ravi, Markus R. Wenk, Jianhong Ching, Philip K. Moore, Diogo Barardo, Nicholas S. Tolwinski, Amaury Cazenave-Gassiot, Tsze Yin Tan, Barry Halliwell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e478f6d60605315c706dc11a3366e25a
https://doi.org/10.7554/elife.50069.033
https://doi.org/10.7554/elife.50069.033