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of 4
pro vyhledávání: '"Emely L. Verweyen"'
Autor:
Emely L. Verweyen, Kairavee Thakkar, Sanjeev Dhakal, Elizabeth Baker, Kashish Chetal, Daniel Schnell, Scott Canna, Alexei A. Grom, Nathan Salomonis, Grant S. Schulert
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Systemic autoimmune and autoinflammatory diseases are characterized by genetic and cellular heterogeneity. While current single-cell genomics methods provide insights into known disease subtypes, these analysis methods do not readily reveal novel cel
Externí odkaz:
https://doaj.org/article/d5179c6c7e644a40aec238db94ea243c
Autor:
Emely L Verweyen, Grant S. Schulert
Publikováno v:
Rheumatology (Oxford)
Systemic JIA (SJIA) is distinguished from other forms of JIA by the prevalence of the severe, life-threatening complications macrophage activation syndrome (SJIA-MAS) and lung disease (SJIA-LD). Alternative therapeutics are urgently needed, as diseas
Autor:
Ysabella M. Esteban, Gwendolyn M. Clay, Grant S. Schulert, Elizabeth Joy Baker, David D. Grier, Jackeline Rodriguez-Smith, Sean M. Lang, Thuy Do, Emely L Verweyen, Alexei A. Grom, Sarah R de Loizaga
Publikováno v:
SSRN Electronic Journal.
Background: Multisystem inflammatory syndrome in children (MIS-C) is a potentially life-threatening hyperinflammatory syndrome that occurs after primary SARS-CoV-2 infection. The pathogenesis of MIS-C remains undefined, and whether specific inflammat
Publikováno v:
Arthritis Rheumatol
OBJECTIVE Canakinumab is a human anti-interleukin-1β (anti-IL-1β) blocking agent that effectively neutralizes IL-1β-mediated signaling for treatment of systemic juvenile idiopathic arthritis (JIA). While many patients have dramatic clinical respon