Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Emeline Perrier‐Groult"'
Autor:
Emeline Perrier-Groult, Shérine Moustaghfir, Marielle Pasdeloup, Jean-Daniel Malcor, Jérôme Lafont, Frédéric Mallein-Gerin
Publikováno v:
Matrix Biology Plus, Vol 18, Iss , Pp 100130- (2023)
Type II collagen is the major fibrillar collagen in cartilage. It is synthesized in the form of precursors (procollagens) containing N- and C-terminal propeptides. The two main isoforms of type II procollagen protein are type IIA and type IIB procoll
Externí odkaz:
https://doaj.org/article/42d7056f7cbe47ea9ef8e0682d56cdbc
Autor:
Alexandre Dufour, Jérôme E. Lafont, Marie Buffier, Michaël Verset, Angéline Cohendet, Hugues Contamin, Joachim Confais, Sharanya Sankar, Marc Rioult, Emeline Perrier-Groult, Frédéric Mallein-Gerin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Articular cartilage is built by chondrocytes which become less active with age. This declining function of the chondrocytes, together with the avascular nature of the cartilage, impedes the spontaneous healing of chondral injuries. These les
Externí odkaz:
https://doaj.org/article/b9869d987c60479f81ee8759550420fe
Publikováno v:
Applied Sciences, Vol 11, Iss 19, p 8923 (2021)
Articular cartilage has limited potential for self-repair, and cell-based strategies combining scaffolds and chondrocytes are currently used to treat cartilage injuries. However, achieving a satisfying level of cell redifferentiation following expans
Externí odkaz:
https://doaj.org/article/9c0d868128254d1db5d8a3f589ff7a09
Autor:
Emeline Perrier-Groult, Eléonore Pérès, Marielle Pasdeloup, Louis Gazzolo, Madeleine Duc Dodon, Frédéric Mallein-Gerin
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217183 (2019)
Articular cartilage (AC) has poor capacities of regeneration and lesions often lead to osteoarthritis. Current AC reconstruction implies autologous chondrocyte implantation which requires tissue sampling and grafting. An alternative approach would be
Externí odkaz:
https://doaj.org/article/dd780eb99aea4dfeb7a412fe1755982a
Autor:
Hugo Fabre, Maxime Ducret, Olivier Degoul, Jonathan Rodriguez, Emeline Perrier-Groult, Elisabeth Aubert-Foucher, Marielle Pasdeloup, Céline Auxenfans, Colin McGuckin, Nico Forraz, Frédéric Mallein-Gerin
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Mesenchymal stem cells (MSCs) represent alternative candidates to chondrocytes for cartilage engineering. However, it remains difficult to identify the ideal source of MSCs for cartilage repair since conditions supporting chondrogenic induction are d
Externí odkaz:
https://doaj.org/article/6f938b70fde247f3abbf677fb681a32d
Autor:
Anne-Laure Durand, Alexandre Dufour, Elisabeth Aubert-Foucher, Christine Oger-Desfeux, Marielle Pasdeloup, Sebastien Lustig, Elvire Servien, Gualter Vaz, Emeline Perrier-Groult, Frederic Mallein-Gerin, Jerome E. Lafont
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6322 (2020)
Osteoarthritis (OA) is a degenerative disease of the joints which is associated with an impaired production of the cartilage matrix by the chondrocytes. Here, we investigated the role of Lysine-Specific Demethylase-1 (LSD1), a chromatin remodeling en
Externí odkaz:
https://doaj.org/article/e8e8c4b21cbb466881f959eb5d96acd3
Autor:
Carole Bougault, Elisabeth Aubert-Foucher, Anne Paumier, Emeline Perrier-Groult, Ludovic Huot, David Hot, Martine Duterque-Coquillaud, Frédéric Mallein-Gerin
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36964 (2012)
Articular cartilage is physiologically exposed to repeated loads. The mechanical properties of cartilage are due to its extracellular matrix, and homeostasis is maintained by the sole cell type found in cartilage, the chondrocyte. Although mechanical
Externí odkaz:
https://doaj.org/article/bdd9f7e4f3e4424ab3728592b59b5ea2
Autor:
Marjorie Dufaud, Lilian Solé, Marie Maumus, Matthieu Simon, Emeline Perrier-Groult, Gilles Subra, Christian Jorgensen, Danièle Noël
Publikováno v:
Bioprinting. 28:e00253
Autor:
Cathrine Nordgaard, Anna Constance Vind, Amy Stonadge, Rasmus Kjøbsted, Goda Snieckute, Pedro Antas, Melanie Blasius, Marie Sofie Reinert, Ana Martinez Del Val, Dorte Breinholdt Bekker‐Jensen, Peter Haahr, Yekaterina A Miroshnikova, Abdelghani Mazouzi, Sarah Falk, Emeline Perrier‐Groult, Christopher Tiedje, Xiang Li, Jens Rithamer Jakobsen, Nicolas Oldenburg Jørgensen, Jørgen FP Wojtaszewski, Frederic Mallein‐Gerin, Jesper Løvind Andersen, Cristian Pablo Pennisi, Christoffer Clemmensen, Moustapha Kassem, Abbas Jafari, Thijn Brummelkamp, Vivian SW Li, Sara A Wickström, Jesper Velgaard Olsen, Gonzalo Blanco, Simon Bekker‐Jensen
Publikováno v:
EMBO Journal
Nordgaard, C, Vind, A C, Stonadge, A, Kjøbsted, R, Snieckute, G, Antas, P, Blasius, M, Reinert, M S, Del Val, A M, Bekker-Jensen, D B, Haahr, P, Miroshnikova, Y A, Mazouzi, A, Falk, S, Perrier-Groult, E, Tiedje, C, Li, X, Jakobsen, J R, Jørgensen, N O, Wojtaszewski, J, Mallein-Gerin, F, Andersen, J L, Pennisi, C P, Clemmensen, C, Kassem, M, Jafari, A, Brummelkamp, T, Li, V S, Wickström, S A, Olsen, J V, Blanco, G & Bekker-Jensen, S 2022, ' ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle ', E M B O Journal, vol. 41, no. 17, e111650 . https://doi.org/10.15252/embj.2022111650
Nordgaard, C, Vind, A C, Stonadge, A, Kjøbsted, R, Snieckute, G, Antas, P, Blasius, M, Reinert, M S, Del Val, A M, Bekker-Jensen, D B, Haahr, P, Miroshnikova, Y A, Mazouzi, A, Falk, S, Perrier-Groult, E, Tiedje, C, Li, X, Jakobsen, J R, Jørgensen, N O, Wojtaszewski, J F, Mallein-Gerin, F, Andersen, J L, Pennisi, C P, Clemmensen, C, Kassem, M, Jafari, A, Brummelkamp, T, Li, V S, Wickström, S A, Olsen, J V, Blanco, G & Bekker-Jensen, S 2022, ' ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle ', The EMBO Journal, vol. 41, no. 17, e111650 . https://doi.org/10.15252/embj.2022111650
Nordgaard, C, Vind, A C, Stonadge, A, Kjøbsted, R, Snieckute, G, Antas, P, Blasius, M, Reinert, M S, Del Val, A M, Bekker-Jensen, D B, Haahr, P, Miroshnikova, Y A, Mazouzi, A, Falk, S, Perrier-Groult, E, Tiedje, C, Li, X, Jakobsen, J R, Jørgensen, N O, Wojtaszewski, J, Mallein-Gerin, F, Andersen, J L, Pennisi, C P, Clemmensen, C, Kassem, M, Jafari, A, Brummelkamp, T, Li, V S, Wickström, S A, Olsen, J V, Blanco, G & Bekker-Jensen, S 2022, ' ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle ', E M B O Journal, vol. 41, no. 17, e111650 . https://doi.org/10.15252/embj.2022111650
Nordgaard, C, Vind, A C, Stonadge, A, Kjøbsted, R, Snieckute, G, Antas, P, Blasius, M, Reinert, M S, Del Val, A M, Bekker-Jensen, D B, Haahr, P, Miroshnikova, Y A, Mazouzi, A, Falk, S, Perrier-Groult, E, Tiedje, C, Li, X, Jakobsen, J R, Jørgensen, N O, Wojtaszewski, J F, Mallein-Gerin, F, Andersen, J L, Pennisi, C P, Clemmensen, C, Kassem, M, Jafari, A, Brummelkamp, T, Li, V S, Wickström, S A, Olsen, J V, Blanco, G & Bekker-Jensen, S 2022, ' ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle ', The EMBO Journal, vol. 41, no. 17, e111650 . https://doi.org/10.15252/embj.2022111650
Mechanical inputs give rise to p38 and JNK activation, which mediate adaptive physiological responses in various tissues. In skeletal muscle, contraction-induced p38 and JNK signaling ensure adaptation to exercise, muscle repair, and hypertrophy. How
Autor:
Hugo Fabre, Marielle Pasdeloup, Jérôme E. Lafont, Elisabeth Aubert-Foucher, Emeline Perrier-Groult, Frédéric Mallein-Gerin
Publikováno v:
Stem Cells and Regenerative Medicine
Type II collagen is the major collagen protein in cartilage, synthesized as precursor forms (procollagens). Several splice variants of the gene encoding type II procollagen have been identified such as IIA and IIB isoforms. Interestingly, a shift fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c100d9ad94cabed42d8049ec34895396
https://doi.org/10.3233/bhr210008
https://doi.org/10.3233/bhr210008