Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Emeline PACREAU"'
Autor:
John TCHEN, Quentin SIMON, Léa CHAPART, Morgane K. THAMINY, Shamila VIBHUSHAN, Loredana SAVEANU, Yasmine LAMRI, Fanny SAIDOUNE, Emeline PACREAU, Christophe PELLEFIGUES, Julie BEX-COUDRAT, Hajime KARASUYAMA, Kensuke MIYAKE, Juan HIDALGO, Padraic G. FALLON, Thomas PAPO, Ulrich BLANK, Marc BENHAMOU, Guillaume HANOUNA, Karim SACRE, Eric DAUGAS, Nicolas CHARLES
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies whose production is promoted by autoreactive T follicular helper (TFH) cells. During SLE pathogenesis, basophils accumulate in secondary
Externí odkaz:
https://doaj.org/article/2b261c12033c4401a2b53ad4f143bfa7
Autor:
Emma Cosialls, Emeline Pacreau, Clémence Duruel, Sara Ceccacci, Rima Elhage, Christophe Desterke, Kevin Roger, Chiara Guerrera, Romane Ducloux, Sylvie Souquere, Gérard Pierron, Ivan Nemazanyy, Mairead Kelly, Elise Dalmas, Yunhua Chang, Vincent Goffin, Maryam Mehrpour, Ahmed Hamaï
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Ferroptosis constitutes a promising therapeutic strategy against cancer by efficiently targeting the highly tumorigenic and treatment-resistant cancer stem cells (CSCs). We previously showed that the lysosomal iron-targeting drug Salinomycin
Externí odkaz:
https://doaj.org/article/5ad5e737bb114cf494300de72b4fe890
Autor:
Christophe Pellefigues, Barbara Dema, Yasmine Lamri, Fanny Saidoune, Nathalie Chavarot, Charlotte Lohéac, Emeline Pacreau, Michael Dussiot, Caroline Bidault, Florian Marquet, Mathieu Jablonski, Jonathan M. Chemouny, Fanny Jouan, Antoine Dossier, Marie-Paule Chauveheid, Delphine Gobert, Thomas Papo, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In a lupus environment, basophils accumulate in secondary lymphoid organs where they affect pathogenesis by stimulating autoantibody production. Here the authors show this accumulation is driven by PGD2-induced CXCR4 surface expression and traffickin
Externí odkaz:
https://doaj.org/article/80954cdc9d4244429cf721f1490b4ce5
Autor:
Barbara Dema, Yasmine Lamri, Christophe Pellefigues, Emeline Pacreau, Fanny Saidoune, Caroline Bidault, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Lupus nephritis (LN), one of the most severe outcomes of systemic lupus erythematosus (SLE), is initiated by glomerular deposition of immune-complexes leading to an inflammatory response and kidney failure. Autoantibodies to nuclear antigens
Externí odkaz:
https://doaj.org/article/d1e831bfa8914cf4b9b64614988ae423
Autor:
Flavie Ngo Nyekel, Emeline Pacreau, Samira Benadda, Rasha Msallam, Magnus Åbrink, Gunnar Pejler, Jean Davoust, Marc Benhamou, Nicolas Charles, Pierre Launay, Ulrich Blank, Gregory Gautier
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Recent evidences indicate an important role of tissue inflammatory responses by innate immune cells in allograft acceptance and survival. Here we investigated the role of mast cells (MC) in an acute male to female skin allograft rejection model using
Externí odkaz:
https://doaj.org/article/19eba69396d14f69908173f038c7f8cf
Autor:
Asma Kassas-Guediri, Julie Coudrat, Emeline Pacreau, Pierre Launay, Renato C Monteiro, Ulrich Blank, Nicolas Charles, Marc Benhamou
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173815 (2017)
Mast cells are critical actors of hypersensitivity type I (allergic) reactions by the release of vasoactive and proinflammatory mediators following their activation by aggregation of the high-affinity receptor for immunoglobulin E (FcεRI). We have p
Externí odkaz:
https://doaj.org/article/31ea533ec4b947b98ac4065826e33043
Autor:
Héloise Boullet, Fayçal Bentot, Arnaud Hequet, Carine Ganem-Elbaz, Chérine Bechara, Emeline Pacreau, Pierre Launay, Sandrine Sagan, Claude Jolivalt, Claire Lacombe, Roba Moumné, Philippe Karoyan
Publikováno v:
Molecules, Vol 24, Iss 9, p 1702 (2019)
Antimicrobial peptides (AMPs) are considered as potential therapeutic sources of future antibiotics because of their broad-spectrum activities and alternative mechanisms of action compared to conventional antibiotics. Although AMPs present considerab
Externí odkaz:
https://doaj.org/article/49975b721d3547de8eb5adf9b7983f7a
Autor:
John Tchen, Quentin Simon, Léa Chapart, Yasmine Lamri, Fanny Saidoune, Emeline Pacreau, Christophe Pellefigues, Julie Bex-Coudrat, Hajime Karasuyama, Kensuke Miyake, Juan Hidalgo, Padraic G. Fallon, Thomas Papo, Ulrich Blank, Marc Benhamou, Guillaume Hanouna, Karim Sacre, Eric Daugas, Nicolas Charles
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibodies raised against nuclear antigens and whose production is promoted by autoreactive T follicular helper (TFH) cells. Basophils, by accumulating in secondary lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89859d8d660a5240c4dd357d58cd075a
https://doi.org/10.1101/2023.01.10.23284399
https://doi.org/10.1101/2023.01.10.23284399
Autor:
Iris K. Madera-Salcedo, Eric Daugas, Emeline Pacreau, Luca Danelli, Maguelonne Pons, Julie Bex-Coudrat, Lydia Celia Madjene, Loïc Rolas, Celine Vaugier, Marc Benhamou, Gunnar Pejler, Walid Beghdadi, Ulrich Blank, Alaa El Ghoneimi, Ivan C. Moura, Julien Claver, Nicolas Charles, Magnus Åbrink, Axel Périanin, Albert Dahdah, Pierre Launay, Shamila Vibhushan
Publikováno v:
Kidney International. 97:516-527
Here we investigated the role of murine mast cell protease 4 (MCPT4), the functional counterpart of human mast cell chymase, in an experimental model of renal ischemia reperfusion injury, a major cause of acute kidney injury. MCPT4-deficient mice had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0261ae4949939eba450d3d96849c6d5e
https://doi.org/10.1016/j.kint.2019.08.037
https://doi.org/10.1016/j.kint.2019.08.037
Autor:
Manon Baures, Emilia Puig Lombardi, Delphine Di Martino, Wail Zeitouni, Emeline Pacreau, Leïla Dos Santos, Charles Dariane, Florence Boutillon, Jacques-Emmanuel Guidotti, Vincent Goffin
Publikováno v:
Cancers; Volume 14; Issue 15; Pages: 3775
Background: The molecular and cellular mechanisms that drive castration-resistant prostate cancer (CRPC) remain poorly understood. LSCmed cells defines an FACS-enriched population of castration-tolerant luminal progenitor cells that has been proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f638e13f3980f88664d426301014ea5d
https://doi.org/10.3390/cancers14153775
https://doi.org/10.3390/cancers14153775