Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Emeline F Nandrot"'
Autor:
Viola Kretschmer, Sandra Schneider, Peter Andreas Matthiessen, Dominik Reichert, Nathan Hotaling, Gunnar Glasßer, Ingo Lieberwirth, Kapil Bharti, Rossella De Cegli, Ivan Conte, Emeline F Nandrot, Helen Louise May-Simera
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002402 (2023)
Vision impairment places a serious burden on the aging society, affecting the lives of millions of people. Many retinal diseases are of genetic origin, of which over 50% are due to mutations in cilia-associated genes. Most research on retinal degener
Externí odkaz:
https://doaj.org/article/9298e4b010bc4863967b740324cfb661
Autor:
Amélie Rodrigues, Amélie Slembrouck-Brec, Céline Nanteau, Angélique Terray, Yelyzaveta Tymoshenko, Yvrick Zagar, Sacha Reichman, Zhouhuan Xi, José-Alain Sahel, Stéphane Fouquet, Gael Orieux, Emeline F. Nandrot, Leah C. Byrne, Isabelle Audo, Jérôme E. Roger, Olivier Goureau
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-22 (2022)
Abstract Mutations in the ubiquitously expressed pre-mRNA processing factor (PRPF) 31 gene, one of the most common causes of dominant form of Retinitis Pigmentosa (RP), lead to a retina-specific phenotype. It is uncertain which retinal cell types are
Externí odkaz:
https://doaj.org/article/9c275654ee034394a4e7eff764d4f7bb
Autor:
Pierre-Henry Gabrielle, Laurence Faivre, Isabelle Audo, Xavier Zanlonghi, Hélène Dollfus, Alberta A. H. J. Thiadens, Christina Zeitz, Grazia M. S. Mancini, Yaumara Perdomo, Saddek Mohand-Saïd, Eléonore Lizé, Vincent Lhussiez, Emeline F. Nandrot, Niyazi Acar, Catherine Creuzot-Garcher, José-Alain Sahel, Muhammad Ansar, Christel Thauvin-Robinet, Laurence Duplomb, Romain Da Costa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cohen syndrome (CS) is a rare syndromic form of rod-cone dystrophy. Recent case reports have suggested that cystoid maculopathy (CM) could affect CS patients with an early onset and high prevalence. Our study aims at improving our understand
Externí odkaz:
https://doaj.org/article/4fba79ce68f2425891072fbe06c9b9c3
Autor:
Sandra Petrus‐Reurer, Pankaj Kumar, Sara Padrell Sánchez, Monica Aronsson, Helder André, Hammurabi Bartuma, Alvaro Plaza Reyes, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 8, Pp 936-953 (2020)
Abstract As pluripotent stem cell (PSC)‐based reparative cell therapies are reaching the bedside, there is a growing need for the standardization of studies concerning safety of the derived products. Clinical trials using these promising strategies
Externí odkaz:
https://doaj.org/article/01aa0cf03b2844ae8af64cc230466355
Autor:
Alvaro Plaza Reyes, Sandra Petrus-Reurer, Sara Padrell Sánchez, Pankaj Kumar, Iyadh Douagi, Hammurabi Bartuma, Monica Aronsson, Sofie Westman, Emma Lardner, Helder André, Anna Falk, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Whilst pigmentation has been used to identify retinal pigment epithelial (RPE) cells, surface markers for these cells remain unclear. Here, the authors define surface markers for the RPE including CD140b, which help produce hPSC-derived RPE cells at
Externí odkaz:
https://doaj.org/article/a87b6c42eab14b69bd24544416acca50
Publikováno v:
Redox Biology, Vol 42, Iss , Pp 101918- (2021)
Methionine sulfoxide reductase A (MsrA) is a widely expressed antioxidant enzyme that counteracts oxidative protein damage and contributes to protein regulation by reversing oxidation of protein methionine residues. In retinal pigment epithelial (RPE
Externí odkaz:
https://doaj.org/article/0efcf6d862c644fc828b83acea40accc
Autor:
Quentin Rieu, Antoine Bougoüin, Yvrick Zagar, Jonathan Chatagnon, Abdallah Hamieh, Julie Enderlin, Thierry Huby, Emeline F. Nandrot
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3445 (2022)
The retinal phagocytic machinery resembles the one used by macrophages to clear apoptotic cells. However, in the retina, the permanent contact between photoreceptor outer segments (POS) and retinal pigment epithelial (RPE) cells requires a tight cont
Externí odkaz:
https://doaj.org/article/5b4317330bf240dd979ad4ba5679e4b6
Autor:
Sara Touhami, Fanny Beguier, Sébastien Augustin, Hugo Charles-Messance, Lucile Vignaud, Emeline F. Nandrot, Sacha Reichman, Valérie Forster, Thibaud Mathis, José-Alain Sahel, Bahram Bodaghi, Xavier Guillonneau, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background The retinal pigment epithelium (RPE) is a monolayer of pigmented cells with important barrier and immuno-suppressive functions in the eye. We have previously shown that acute stimulation of RPE cells by tumor necrosis factor alpha
Externí odkaz:
https://doaj.org/article/2369fd9a9a4e4fbe823a939388eed809
Autor:
Laurence Klipfel, Marie Cordonnier, Léa Thiébault, Emmanuelle Clérin, Frédéric Blond, Géraldine Millet-Puel, Saddek Mohand-Saïd, Olivier Goureau, José-Alain Sahel, Emeline F. Nandrot, Thierry Léveillard
Publikováno v:
Cells, Vol 10, Iss 1, p 179 (2021)
Age-related macular degeneration (AMD) is a blinding disease for which most of the patients remain untreatable. Since the disease affects the macula at the center of the retina, a structure specific to the primate lineage, rodent models to study the
Externí odkaz:
https://doaj.org/article/8b4b34875552484aad259f5a5bb6ca1c
Autor:
Alvaro Plaza Reyes, Sandra Petrus-Reurer, Sara Padrell Sánchez, Pankaj Kumar, Iyadh Douagi, Hammurabi Bartuma, Monica Aronsson, Sofie Westman, Emma Lardner, Helder André, Anna Falk, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/5f6569547e404b8a939dfc0fd45a3443