Výsledky vyhledávání - "Emeline Dudognon"

Akademický článek

Impact of Hot-Melt Extrusion on Glibenclamide’s Physical and Chemical States and Dissolution Behavior: Case Studies with Three Polymer Blend Matrices

Autor: Nina Zupan, Ines Yous, Florence Danede, Jeremy Verin, Mostafa Kouach, Catherine Foulon, Emeline Dudognon, Susanne Florin Muschert

Publikováno v: Pharmaceutics, Vol 16, Iss 8, p 1071 (2024)

This research work dives into the complexity of hot-melt extrusion (HME) and its influence on drug stability, focusing on solid dispersions containing 30% of glibenclamide and three 50:50 polymer blends. The polymers used in the study are Ethocel Sta

Externí odkaz: https://doaj.org/article/fcc252bba23d4e36a21bb0dc73412271

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Milling-induced Phase Transformations, Underlying Mechanisms and Resulting Physical States in an Enantiotropic System: the Case of Bezafibrate

Autor: Florence Danede, Emeline Dudognon, Mathieu Guerain

Publikováno v: Crystal Growth & Design
Crystal Growth & Design, 2022, Crystal Growth & Design, 22 (1), pp.363-378. ⟨10.1021/acs.cgd.1c00997⟩

International audience; The mechanisms driving the milling-induced transformations of an enantiotropic polymorph system, Bezafibrate, are depicted. The phase transformations promoted by milling at two different temperatures and the resulting physical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a280b2295a6a22dd7ee690e1b8ebeb75
https://hal.univ-lille.fr/hal-03537652

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Molecular Mobility of Terfenadine: Investigation by Dielectric Relaxation Spectroscopy and Molecular Dynamics Simulation

Autor: Jeanne-Annick Bama, Frédéric Affouard, Emeline Dudognon

Publikováno v: Molecular Pharmaceutics
Molecular Pharmaceutics, 2019, Molecular Pharmaceutics, 16 (11), pp.4711-4724. ⟨10.1021/acs.molpharmaceut.9b00877⟩

The molecular mobility of an amorphous active pharmaceutical ingredient, terfenadine, was carefully investigated by dielectric relaxation spectroscopy and molecular dynamics simulation for the first time. Comprehensive characterization on a wide freq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedd8a922cc5339ba9a0ede76937537b
https://doi.org/10.1021/acs.molpharmaceut.9b00877

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The role of cracks in the crystal nucleation process of amorphous griseofulvin

Autor: Aurélien Mahieu, Emeline Dudognon, Mark D. Eddleston, William Jones, Jean-François willart, Marc Descamps

Publikováno v: The European Physical Journal Special Topics. 226:837-847

In this paper we have investigated the recrystallization properties of amorphous griseofulvin obtained by melt quenching. We have shown that the maximum nucleation rates of crystalline forms 2 and 3 are located around the glass transition temperature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::994e328aba4da33ed11875d0d2880186
https://doi.org/10.1140/epjst/e2016-60358-y

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Investigation of complex molecular dynamics in multi-component systems

Autor: Jeanne Annick Bama, Emeline Dudognon, Frédéric Affouard

Publikováno v: BIOFIT MARSEILLE-INTERREG 2 Seas IMODE Project Fourth annual convention
BIOFIT MARSEILLE-INTERREG 2 Seas IMODE Project Fourth annual convention, Dec 2019, Marseille, France
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International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bafa51b9dda4e4c109a5deb82d4f3dc4
https://hal.univ-lille.fr/hal-02430088

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The Amorphous State

Autor: Jean-François willart, Emeline Dudognon, Marc Descamps

Publikováno v: Polymorphism in the Pharmaceutical Industry
Polymorphism in the Pharmaceutical Industry, Wiley-VCH Verlag GmbH & Co. KGaA, pp.189-239, 2018, ⟨10.1002/9783527697847.ch7⟩
Polymorphism in the Pharmaceutical Industry Solid Form and Drug Development
Hilfiker, Rolf; von Raumer, Markus. Polymorphism in the Pharmaceutical Industry Solid Form and Drug Development, Wiley-VCH, p. 189-240, 2019, 978-3-527-34040-8
Polymorphism in the Pharmaceutical Industry, Wiley-VCH Verlag GmbH & Co. KGaA, pp.189-239, 2018

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb8ce3acf986fdd4971067e634f280e
https://hal.archives-ouvertes.fr/hal-02364084

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Structural Transformations of d -Mannitol Induced by in Situ Milling Using Real Time Powder Synchrotron Radiation Diffraction

Autor: Jean-François willart, William Pagnoux, Emeline Dudognon, Pauline Martinetto, Pierre Bordet, Marc Descamps

Publikováno v: Crystal Growth and Design
Crystal Growth and Design, American Chemical Society, 2017, 17 (11), pp.6111-6122. ⟨10.1021/acs.cgd.7b01283⟩
Crystal Growth & Design
Crystal Growth & Design, 2017, 17 (11), pp.6111-6122. ⟨10.1021/acs.cgd.7b01283⟩
Crystal Growth & Design, American Chemical Society, 2017, 17 (11), pp.6111-6122. ⟨10.1021/acs.cgd.7b01283⟩

We have investigated the solid-state transformation of anhydrous β-d-mannitol upon milling using synchrotron X-ray powder diffraction. The 1720 diffraction patterns, collected in real time during the operation of the mill (6 h), have been analyzed b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f6c2c6c8604a90df0fa2f6fdfd3e3d
https://hal.archives-ouvertes.fr/hal-01647796

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Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate

Autor: Natália T. Correia, Marc Descamps, Adrien Benazzouz, Valérie Molinier, Jean-Marie Aubry, Emeline Dudognon

Publikováno v: Cellulose
Cellulose, 2017, Cellulose, 24, pp.487-503. ⟨10.1007/s10570-016-1148-y⟩

International audience; This work establishes that the plasticization effect of a classical petrochemical plasticizer, dimethyl phthalate (DMP), on a polymer matrix, cellulose acetate (CA), is due to the development of intermolecular interactions of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbefe579a986c242a197a2d334b8b52
https://hal.univ-lille.fr/hal-03252483

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On the Polymorphism of Griseofulvin: Identification of Two Additional Polymorphs

Autor: Aurélien Mahieu, Mark D. Eddleston, William Jones, Jean-François willart, Marc Descamps, Emeline Dudognon, Florence Danede

Publikováno v: Journal of Pharmaceutical Sciences. 102:462-468

In this paper, we present an investigation of the polymorphism of griseofulvin. In addition to the only reported crystalline form (form I), two new polymorphic forms (II and III) have been identified and characterized by differential scanning calorim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5b54572f6d6f6ef0322019fcf75012
https://doi.org/10.1002/jps.23349

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Solid State Amorphization of β-Trehalose: A Structural Investigation Using Synchrotron Powder Diffraction and PDF Analysis

Autor: Pierre Bordet, William Pagnoux, Emeline Dudognon, Agnieszka Poulain, Pauline Martinetto, Jean-François willart, Erik Elkaim, Marc Descamps, Aleksei Bytchkov

Publikováno v: Crystal Growth and Design
Crystal Growth and Design, American Chemical Society, 2016, 16 (8), pp.4547-4558. ⟨10.1021/acs.cgd.6b00660⟩
Crystal Growth & Design
Crystal Growth & Design, American Chemical Society, 2016, 16 (8), pp.4547-4558. ⟨10.1021/acs.cgd.6b00660⟩
Crystal Growth & Design, 2016, 16 (8), pp.4547-4558. ⟨10.1021/acs.cgd.6b00660⟩

International audience; We have investigated the amorphization of β-trehalose by high energy milling using in situ and ex situ synchrotron powder diffraction and PDF analysis. From this analysis we show that amorphization takes place through a two-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9bb25b10c4fc280f8762eeb198f844
https://hal.archives-ouvertes.fr/hal-01355791

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