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pro vyhledávání: '"Emelie Hamelin"'
Autor:
Renata M. Oballa, Liette Belair, W. Cameron Black, Kelly Bleasby, Chi Chung Chan, Carole Desroches, Xiaobing Du, Robert Gordon, Jocelyne Guay, Sebastien Guiral, Michael J. Hafey, Emelie Hamelin, Zheng Huang, Brian Kennedy, Nicolas Lachance, France Landry, Chun Sing Li, Joseph Mancini, Denis Normandin, Alessandro Pocai, David A. Powell, Yeeman K. Ramtohul, Kathryn Skorey, Dan Sørensen, Wayne Sturkenboom, Angela Styhler, Deena M. Waddleton, Hao Wang, Simon Wong, Lijing Xu, Lei Zhang
Publikováno v:
Journal of medicinal chemistry. 54(14)
The potential use of SCD inhibitors for the chronic treatment of diabetes and dyslipidemia has been limited by preclinical adverse events associated with inhibition of SCD in skin and eye tissues. To establish a therapeutic window, we embarked on des