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pro vyhledávání: '"Emel Arinc"'
Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with ge
Proceedings of a NATO ASI held in Antalya, Turkey, August 31 - September 11, 1997
Proceedings of a NATO ASI held in Çesme (Izmir), Turkey, August 27-September 7, 1989.
Publikováno v:
Journal of biochemical and molecular toxicology. 28(6)
The primary objective of this study was to determine specific cytochrome P450 isozyme(s) involved in the metabolism of aldrin to its toxic metabolite dieldrin in flathead mullet (Mugil cephalus) liver microsomes. To identify the cytochrome P450 isozy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9cce737bfcbc51d94d8af09ca1a8bf61
https://pubmed.ncbi.nlm.nih.gov/24756956
https://pubmed.ncbi.nlm.nih.gov/24756956
Publikováno v:
Biochemical Journal. 143:733-744
A relatively simple method is described by which cholinesterase was purified about 19000-fold starting from horse serum. Typically 20 litres of serum were processed to yield 15-18mg of electrophoretically pure cholinesterase in the form of an active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0f90b7f0b4b5b399bf2aa03c5bb04d
https://doi.org/10.1042/bj1430733
https://doi.org/10.1042/bj1430733
Autor:
Haydar Çelik, Emel Arinç
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 13, Iss 2 (2010)
PURPOSE. Idarubicin is a synthetic anthracycline anticancer drug widely used in the treatment of some hematological malignancies. The studies in our laboratory have clearly demonstrated that idarubicin can undergo reductive bioactivation by NADPH-cyt
Externí odkaz:
https://doaj.org/article/a9a1b7d78abf444baf8b2b0aeb6489c7
Autor:
Haydar Çelik, Emel Arinç
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 11, Iss 4 (2009)
PURPOSE. Idarubicin is a clinically effective synthetic anthracycline analog used in the treatment of several human neoplasms. Anthracyclines have the potential to undergo bioactivation by flavoenzymes to free radicals and thus exert their cytotoxic
Externí odkaz:
https://doaj.org/article/85008972da384d39be0693940487d96d
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