Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells"'
Autor:
Koji Eto, Tatsutoshi Nakahata, Shoichi Hirose, Hiromitsu Nakauchi, Naoya Takayama, Kiyosumi Ochi
Publikováno v:
Stem Cells Translational Medicine. 3:792-800
Adult hemoglobin composed of α- and β-globin reflects a change from expression of embryonic ε- and fetal γ-globin to adult β-globin in human erythroid cells, so-called globin switching. Human pluripotent stem cells (hPSCs) are a potential source
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c948400a40945afeb8f4f94ce7ef5115
https://doi.org/10.5966/sctm.2013-0216
https://doi.org/10.5966/sctm.2013-0216
Autor:
Mi Yoon Chang, Sanghyeok Ko, Paulo Sng Man Yoo, Jeong Tae Do, Robert Lanza, Chengsheng Zhang, Kwang Soo Kim, Rebecca C. Iskow, Dohoon Kim, Min-Joon Han, Chun-Hyung Kim, Hansoo Park, Eun Gyo Lee, Ryan E. Mills, Hyun Woo Choi, Jung Il Moon, Joon Ki Jung
Publikováno v:
Stem Cells Translational Medicine. 3:599-609
It has recently been shown that genomic integrity (with respect to copy number variants [CNVs]) is compromised in human induced pluripotent stem cells (iPSCs) generated by viral-based ectopic expression of specific transcription factors (e.g., Oct4,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8ca94cf019147078d852bbdfd8c93c
https://doi.org/10.5966/sctm.2013-0149
https://doi.org/10.5966/sctm.2013-0149
Publikováno v:
Riazifar, H; Jia, Y; Chen, J; Lynch, G; & Huang, T. (2014). Chemically induced specification of retinal ganglion cells from human embryonic and induced pluripotent stem cells. Stem Cells Translational Medicine, 3(4), 424-432. doi: 10.5966/sctm.2013-0147. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/88f2s80h
The loss of retinal ganglion cells (RGCs) is the primary pathological change for many retinal degenerative diseases. Although there is currently no effective treatment for this group of diseases, cell transplantation to replace lost RGCs holds great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb56a035aff17b4da9709018294f20c6
https://doi.org/10.5966/sctm.2013-0147
https://doi.org/10.5966/sctm.2013-0147
Autor:
Kevin Lai, Thuy Ai Huyen Le, Monica Bennett, Bahram Valamehr, Peter Flynn, David J. Robbins, Tom Tong Lee, Ramzey Abujarour, Megan Robinson
Publikováno v:
Stem Cells Translational Medicine. 3:149-160
Human induced pluripotent stem cells (iPSCs) represent a scalable source of potentially any cell type for disease modeling and therapeutic screening. We have a particular interest in modeling skeletal muscle from various genetic backgrounds; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8d53b64ad2906d1741bb66fcd17ed5
https://doi.org/10.5966/sctm.2013-0095
https://doi.org/10.5966/sctm.2013-0095
Autor:
Noushin Dianat, Inmaculada Moreno-Gimeno, Eléanor Luce, Anne Dubart-Kupperschmitt, Gérard Tachdjian, Joëlle Marie, Clara Steichen, Lucie Tosca, Jérome Maluenda, Deborah J. Burks, Christophe Desterke, Judith Melki, Sylvie Goulinet-Mainot, Sarah Awan-Toor, Anne Weber
Publikováno v:
Stem Cells Translational Medicine
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
The use of synthetic messenger RNAs to generate human induced pluripotent stem cells (iPSCs) is particularly appealing for potential regenerative medicine applications, because it overcomes the common drawbacks of DNA-based or virus-based reprogrammi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91942aa5c29f66c97ae603704f6872f3
Autor:
Susana Villate, Camillo Ricordi, R. D. Molano, Christopher A. Fraker, Antonello Pileggi, Silvia Álvarez-Cubela, Luca Inverardi, Sirlene Cechin, Jaime A. Giraldo, Juan Domínguez-Bendala
Publikováno v:
Stem Cells Translational Medicine. 3:277-289
The possibility of using human embryonic stem (hES) cell-derived β cells as an alternative to cadaveric islets for the treatment of type 1 diabetes is now widely acknowledged. However, current differentiation methods consistently fail to generate me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e884e894662cf9076c87fba9e4e55b
https://doi.org/10.5966/sctm.2013-0160
https://doi.org/10.5966/sctm.2013-0160
Autor:
Chi-Wing Kong, Deborah K. Lieu, Roger J. Hajjar, Francesca Stillitano, Grant Senyei, Lihuan Ren, Ioannis Karakikes, Evren U. Azeloglu, Ravi Iyengar, Jiaxian Wang, Jens Hansen, Jean-Sébastien Hulot, Ronald A. Li
Publikováno v:
Stem Cells Translational Medicine. 3:18-31
The generation of human ventricular cardiomyocytes from human embryonic stem cells and/or induced pluripotent stem cells could fulfill the demand for therapeutic applications and in vitro pharmacological research; however, the production of a homogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdd4c799d067576093fc2f7bfa80b27
https://doi.org/10.5966/sctm.2013-0110
https://doi.org/10.5966/sctm.2013-0110
Autor:
Brendan A.S. McIntyre, Borhane Guezguez, Rami Mechael, Mickie Bhatia, Aline Fiebig-Comyn, Yuping Wu, Kyle R. Salci, Jung Bok Lee, Guojun Sheng, Cantas Alev
Publikováno v:
Stem Cells Translational Medicine. 3:7-17
Production of human embryonic stem cell (hESC)-derived lung progenitors has broad applicability for drug screening and cell therapy; however, this is complicated by limitations in demarcating phenotypic changes with functional validation of airway ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d351a55f74b2dfcf02f1bd09aa722c
https://doi.org/10.5966/sctm.2013-0119
https://doi.org/10.5966/sctm.2013-0119
Autor:
Rui-Zhe Phang, Wee Kiat Tan, Han Chong Toh, Johan Chin-Kang Tay, Felix Chang Tay, Zhendong Li, Sal-Lee Goh, Cia-Hin Lau, Haibao Zhu, Can Chen, Shouhui Du, Weimin Fan, Chunxiao Wu, Shu Wang, Jieming Zeng, Qingle Liang
Publikováno v:
Stem Cells Translational Medicine. 2:935-945
Integrative gene transfer using retroviruses to express reprogramming factors displays high efficiency in generating induced pluripotent stem cells (iPSCs), but the value of the method is limited because of the concern over mutagenesis associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87692140c008d4085bd42e97a10f4b4a
https://doi.org/10.5966/sctm.2013-0043
https://doi.org/10.5966/sctm.2013-0043
Publikováno v:
Stem Cells Translational Medicine. 2:929-934
Glut2 is one of the facilitative glucose transporters expressed by preimplantation and early postimplantation embryos. Glut2 is important for survival before embryonic day 10.5. The Glut2 KM (∼16 mmol/liter) is significantly higher than physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2353fa07ce1f50771648c3ad16de94d1
https://doi.org/10.5966/sctm.2013-0093
https://doi.org/10.5966/sctm.2013-0093