Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Embryonic Development/ genetics"'
Autor:
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Liesbeth Harkema, Sameh A Youssef, Natalie Beschorner, Anouk HG Wolters, Bjorn Bakker, Lore Becker, Lilian Garrett, Susan Marschall, Sabine M Hoelter, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabe de Angelis, Amantha Thathiah, Floris Foijer, Bart van de Sluis, Jan van Deursen, Matthias Jucker, Alain de Bruin, Ellen AA Nollen
Publikováno v:
Life science alliance 6(7), e202201730 (2023). doi:10.26508/lsa.202201730
In age-related neurodegenerative diseases, like Alzheimer’s and Parkinson’s, disease-specific proteins become aggregation-prone and form amyloid-like deposits. Depletion of SERF proteins ameliorates this toxic process in worm and human cell model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2dc28445569fccfa99cc8b093ea779
https://pub.dzne.de/record/257883
https://pub.dzne.de/record/257883
Autor:
Ileana Mateizel, Samuel Santos-Ribeiro, Ingrid Segers, Koen Wouters, Shari Mackens, Greta Verheyen
Publikováno v:
J Assist Reprod Genet
PURPOSE: To investigate whether treatment with commercially available ready-to-use A23187 ionophore (GM508-CultActive) improves embryo development outcome in patients with a history of embryo developmental problems. METHODS: This is a uni-center pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f09344364950297f08d0f3b3b65bc91
https://hdl.handle.net/20.500.14017/53e9ec71-1804-447f-aca5-d68becc8d39b
https://hdl.handle.net/20.500.14017/53e9ec71-1804-447f-aca5-d68becc8d39b
Autor:
Weiting Zhang, Pierluigi Scerbo, Marine Delagrange, Virginie Candat, Vanessa Mayr, Sophie Vriz, Martin Distel, Bertrand Ducos, David Bensimon
Publikováno v:
Communications Biology
Communications Biology, 2022, 5 (1), pp.113. ⟨10.1038/s42003-022-03053-0⟩
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Communications Biology, 2022, 5 (1), pp.113. ⟨10.1038/s42003-022-03053-0⟩
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Somitogenesis, the segmentation of the antero-posterior axis in vertebrates, is thought to result from the interactions between a genetic oscillator and a posterior-moving determination wavefront. The segment (somite) size is set by the product of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdacdfae2027ebc39a515e0e9270e64
https://doi.org/10.1038/s42003-022-03053-0
https://doi.org/10.1038/s42003-022-03053-0
Autor:
Chang Liu, Rui Li, Young Li, Xiumei Lin, Kaichen Zhao, Qun Liu, Shuowen Wang, Xueqian Yang, Xuyang Shi, Yuting Ma, Chenyu Pei, Hui Wang, Wendai Bao, Junhou Hui, Tao Yang, Zhicheng Xu, Tingting Lai, Michael Arman Berberoglu, Sunil Kumar Sahu, Miguel A. Esteban, Kailong Ma, Guangyi Fan, Yuxiang Li, Shiping Liu, Ao Chen, Xun Xu, Zhiqiang Dong, Longqi Liu
Publikováno v:
Liu, C, Li, R, Li, Y, Lin, X, Zhao, K, Liu, Q, Wang, S, Yang, X, Shi, X, Ma, Y, Pei, C, Wang, H, Bao, W, Hui, J, Yang, T, Xu, Z, Lai, T, Berberoglu, M A, Sahu, S K, Esteban, M A, Ma, K, Fan, G, Li, Y, Liu, S, Chen, A, Xu, X, Dong, Z & Liu, L 2022, ' Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis ', Developmental Cell, vol. 57, no. 10, pp. 1284-1298.e5 . https://doi.org/10.1016/j.devcel.2022.04.009
A major challenge in understanding vertebrate embryogenesis is the lack of topographical transcriptomic information that can help correlate microenvironmental cues within the hierarchy of cell-fate decisions. Here, we employed Stereo-seq to profile 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbed7f2f3e2cee862545dfe47a3b38e
https://curis.ku.dk/portal/da/publications/spatiotemporal-mapping-of-gene-expression-landscapes-and-developmental-trajectories-during-zebrafish-embryogenesis(f032e4ac-9899-4cdf-9ba5-a35175dd3b5f).html
https://curis.ku.dk/portal/da/publications/spatiotemporal-mapping-of-gene-expression-landscapes-and-developmental-trajectories-during-zebrafish-embryogenesis(f032e4ac-9899-4cdf-9ba5-a35175dd3b5f).html
Autor:
Jialin Liu, James P. Reddington, Marc Robinson-Rechavi, Rebecca Rodríguez Viales, Pierre Khoueiry, Eileen E. M. Furlong, Charles Girardot
Publikováno v:
Genome research, vol. 31, no. 9, pp. 1573-1581
Genome Res
Genome Res
Inter-species comparisons of both morphology and gene expression within a phylum have revealed a period in the middle of embryogenesis with more similarity between species compared with earlier and later time points. This “developmental hourglass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63bf8637919ffe98f6259d867e3c86b7
https://serval.unil.ch/resource/serval:BIB_7EF03DE26E06.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_7EF03DE26E06.P001/REF.pdf
Autor:
Susana M. Chuva de Sousa Lopes, Björn Heindryckx, Maya Sen, Jean-Charles Boisset, Dylan Mooijman, Alexander van Oudenaarden, Alex Chialastri, Siddharth S. Dey, Mina Popovic
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
NATURE COMMUNICATIONS
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 12. NATURE RESEARCH
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
NATURE COMMUNICATIONS
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 12. NATURE RESEARCH
DNA methylation (5mC) is central to cellular identity. The global erasure of 5mC from the parental genomes during preimplantation mammalian development is critical to reset the methylome of gametes to the cells in the blastocyst. While active and pas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db94af2adb78a740a8e504e4a4e14be
http://europepmc.org/articles/PMC7904860
http://europepmc.org/articles/PMC7904860
Autor:
Emma M. Jenkinson, Andrew P. Badrock, Denis L. J. Lafontaine, Gillian I. Rice, Raymond T. O'Keefe, Siobhan Crilly, Paul R. Kasher, Ludivine Wacheul, Carolina Uggenti, Yanick J. Crow
Publikováno v:
Am J Hum Genet
Badrock, A, Uggenti, C, Wacheul, L, Crilly, S, Jenkinson, E, Rice, G, Kasher, P, Lafontaine, D, Crow, Y & O'Keefe, R 2020, ' Analysis of U8 snoRNA Variants in Zebrafish Reveals how Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts ', American Journal of Human Genetics, vol. 106, no. 5, pp. 694-706 . https://doi.org/10.1016/j.ajhg.2020.04.003
Badrock, A P, Uggenti, C, Wacheul, L, Crilly, S, Jenkinson, E M, Rice, G I, Kasher, P R, Lafontaine, D L J, Crow, Y J & O'Keefe, R T 2020, ' Analysis of U8 snoRNA Variants in Zebrafish Reveals how Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts ', American Journal of Human Genetics, vol. 106, no. 5, pp. 694-706 . https://doi.org/10.1016/j.ajhg.2020.04.003
American journal of human genetics, 106 (5
Badrock, A, Uggenti, C, Wacheul, L, Crilly, S, Jenkinson, E, Rice, G, Kasher, P, Lafontaine, D, Crow, Y & O'Keefe, R 2020, ' Analysis of U8 snoRNA Variants in Zebrafish Reveals how Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts ', American Journal of Human Genetics, vol. 106, no. 5, pp. 694-706 . https://doi.org/10.1016/j.ajhg.2020.04.003
Badrock, A P, Uggenti, C, Wacheul, L, Crilly, S, Jenkinson, E M, Rice, G I, Kasher, P R, Lafontaine, D L J, Crow, Y J & O'Keefe, R T 2020, ' Analysis of U8 snoRNA Variants in Zebrafish Reveals how Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts ', American Journal of Human Genetics, vol. 106, no. 5, pp. 694-706 . https://doi.org/10.1016/j.ajhg.2020.04.003
American journal of human genetics, 106 (5
How mutations in the non-coding U8 snoRNA cause the neurological disorder leukoencephalopathy with calcifications and cysts (LCC) is poorly understood. Here, we report the generation of a mutant U8 animal model for interrogating LCC-associated pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849cb23302137c98d55f60d6c34d5a35
https://pubmed.ncbi.nlm.nih.gov/32359472
https://pubmed.ncbi.nlm.nih.gov/32359472
Autor:
Cindy Serafim, Luís Antunes, Sandra M. Monteiro, Ana M. Coimbra, Luís M. Félix, Ana M. Vidal, Manuela Matos, Ana M. Valentim
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Ketamine is a widely used pharmaceutical that has been detected in water sources worldwide. Zebrafish embryos were used in this study to investigate the oxidative stress and apoptotic signals following a 24h exposure to different ketamine concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a793dec97f12a30646ab094d36742379
https://doi.org/10.1016/j.chemosphere.2018.03.049
https://doi.org/10.1016/j.chemosphere.2018.03.049
Publikováno v:
Cells, Vol 9, Iss 1590, p 1590 (2020)
Cells
Cells
Non-muscle myosin 2A (NM2A) is a motor cytoskeletal enzyme with crucial importance from the early stages of development until adulthood. Due to its capacity to convert chemical energy into force, NM2A powers the contraction of the actomyosin cytoskel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfb2effb428aed032bf8004e2812d38
https://hdl.handle.net/10216/143490
https://hdl.handle.net/10216/143490
Autor:
Florence L Marlow
Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by one or more members of an international board of authors. - Provides the authority a