Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Emanuell dos Santos Silva"'
Autor:
Aline de Sousa Barbosa Freitas Pereira, Maria Laura de Souza Lima, Arnobio Antonio da Silva-Junior, Emanuell dos Santos Silva, Raimundo Fernandes de Araújo Júnior, Agnes Andrade Martins, Jovelina Samara Ferreira Alves, Artur de Santana Oliveira, Leandro De Santis Ferreira, Emily Cintia Tossi de Araújo Costa, Gerlane Coelho Bernardo Guerra, Caroline Addison Carvalho Xavier de Medeiros, Gerly A. C. Brito, Renata Ferreira de Carvalho Leitao, Aurigena Antunes de Araújo
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1576-1584 (2021)
Context Metformin is an important oral anti-hyperglycemic used in diabetes. Polylactic-co-glycolic acid (PLGA) has been widely used due to its reliability in controlling the release of drugs. Objective This study evaluates the in vitro-in vivo availa
Externí odkaz:
https://doaj.org/article/7d4d72e176694e5aa3a792b23b8a3c96
Autor:
Emanuell dos Santos-Silva, Manoela Torres-Rêgo, Fiamma Gláucia-Silva, Renata Carvalho Feitosa, Ariane Ferreira Lacerda, Hugo Alexandre de Oliveira Rocha, Matheus de Freitas Fernandes-Pedrosa, Arnóbio Antônio da Silva-Júnior
Publikováno v:
Toxins, Vol 14, Iss 12, p 888 (2022)
Snakebite envenoming represents a worldwide public health issue. Suitable technologies have been investigated for encapsulated recombinant or native proteins capable of inducing an effective and long-lasting adaptive immune response. Nanoparticles ar
Externí odkaz:
https://doaj.org/article/4c3a01763543429ba3a9b097fe44757b
Autor:
Tábata Loíse Cunha Lima, Renata de Carvalho Feitosa, Emanuell dos Santos-Silva, Alaine Maria dos Santos-Silva, Emerson Michell da Silva Siqueira, Paula Renata Lima Machado, Alianda Maira Cornélio, Eryvaldo Sócrates Tabosa do Egito, Matheus de Freitas Fernandes-Pedrosa, Kleber Juvenal Silva Farias, Arnóbio Antônio da Silva-Júnior
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 255 (2018)
Chloroquine diphosphate (CQ) is a hydrophilic drug with low entrapment efficiency in hydrophobic nanoparticles (NP). Herpes simplex virus type 1 (HSV-1) is an enveloped double-stranded DNA virus worldwide known as a common human pathogen. This study
Externí odkaz:
https://doaj.org/article/240dc48e2f034575a40032f01c7864ba
Autor:
Emily Cintia Tossi de Araújo Costa, Artur de Santana Oliveira, Aline de Sousa Barbosa Freitas Pereira, Emanuell Dos Santos Silva, Gerly Anne de Castro Brito, Caroline Addison Carvalho Xavier de Medeiros, Aurigena Antunes de Araújo, Jovelina Samara Ferreira Alves, Raimundo Fernandes de Araújo Júnior, Agnes Andrade Martins, Maria Laura de Souza Lima, Gerlane Coelho Bernardo Guerra, Arnóbio Antônio da Silva-Júnior, Renata Ferreira de Carvalho Leitão, Leandro de Santis Ferreira
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1576-1584 (2021)
Pharmaceutical Biology
article-version (VoR) Version of Record
Pharmaceutical Biology
article-version (VoR) Version of Record
Context Metformin is an important oral anti-hyperglycemic used in diabetes. Polylactic-co-glycolic acid (PLGA) has been widely used due to its reliability in controlling the release of drugs. Objective This study evaluates the in vitro-in vivo availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584cd6364aedba491793ea3e1c57a105
https://doaj.org/article/7d4d72e176694e5aa3a792b23b8a3c96
https://doaj.org/article/7d4d72e176694e5aa3a792b23b8a3c96
Autor:
Rômulo S. Cavalcante, Emanuell Dos Santos Silva, Arnóbio Antônio da Silva-Júnior, Raimundo Fernandes de Araújo Júnior, Luis J. Cruz, Aurigena Antunes de Araújo, Alan Chan, Uta Ishikawa
Publikováno v:
British Journal of Pharmacology
British Journal of Pharmacology, 178(11), 2284-2304. WILEY
British Journal of Pharmacology, 178(11), 2284-2304. WILEY
Background and Purpose Inflammation associated with the tumour microenvironment (TME) is critical for cancer development, and immunotherapeutic strategies modulating the immune response in cancer have been crucial. In this study, a methotrexate-loade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88575501bdb96170f37bf1067d3ab4d1
https://hdl.handle.net/1887/3277573
https://hdl.handle.net/1887/3277573
Autor:
Emanuell dos-Santos-Silva, Eryvaldo Sócrates Tabosa do Egito, Juliana S. de Medeiros, Rômulo dos Santos-Cavalcante, Matheus F. Fernandes-Pedrosa, Mariana Farias Alves-Silva, Arnóbio Antônio da Silva-Júnior, Alianda Maira Cornélio, Raimundo F. de Araújo-Júnior
Publikováno v:
Journal of Molecular Liquids. 315:113721
This study explores the hypothesis that the colloidal properties of nanocarriers can modulate the interaction of hydrophilic and anionic chemotherapy agents with biological surfaces, especially tumoral cells. Different compositions were tested for pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1f8821589daf285a2c83fe3111e9f7
https://doi.org/10.1016/j.molliq.2020.113721
https://doi.org/10.1016/j.molliq.2020.113721
Autor:
Flavia Q. Pirih, Maria Galvan, Gerlane Coelho Bernando Guerra, Emanuell Dos Santos Silva, Raimundo Fernandes de Araújo Júnior, Aline de Sousa Barbosa Freitas Pereira, Arnóbio Antônio da Silva Júnior, Caroline Addison Carvalho Xavier de Medeiros, Maria Laura de Souza Lima, Adriana Augusto de Rezende, Gerly Anne de Castro Brito, Aurigena Antunes de Araújo, Raul Hernandes Bortolin
The aim of this study was synthesize and evaluate the effects of Poly (D, L-Lactide-co-glycolide) (PLGA) Nanoparticles (NPs) of metformin (PLGA+ Met) on inflammation, and bone loss in a ligature-induced periodontitis rat model. The prepared NPs were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9c40fc72069eb3884997e888fcfe18
Autor:
Matheus F. Fernandes-Pedrosa, Luanda Bárbara Ferreira Canário de Souza, Fiamma Gláucia-Silva, Karla Samara Rocha Soares, Arnóbio Antônio da Silva-Júnior, Emanuell dos Santos-Silva, Ariane F. Lacerda, Manoela Torres-Rêgo, Guilherme Maranhão Chaves, Igor Zumba Damasceno
Publikováno v:
Materials Science and Engineering: C. 103:109830
Among several bioactive peptides identified from the venom glands of the Tityus stigmurus scorpion, one peptide with hypotensive action (TistH, Tityus stigmurus Hypotensin) showed multifunctional and biotechnological applications. The maximum efficac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dca240ad58e9e1ee51a734c49d84dde
https://doi.org/10.1016/j.msec.2019.109830
https://doi.org/10.1016/j.msec.2019.109830
Autor:
Renata de Carvalho Feitosa, Tábata L. C. Lima, Alianda Maira Cornélio, Kleber Juvenal Silva Farias, Paula Renata Lima Machado, Arnóbio Antônio da Silva-Júnior, Eryvaldo Sócrates Tabosa do Egito, Alaine M. dos Santos-Silva, Emerson Michell da Silva Siqueira, Matheus F. Fernandes-Pedrosa, Emanuell dos Santos-Silva
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 10, Iss 4, p 255 (2018)
Volume 10
Issue 4
Pharmaceutics, Vol 10, Iss 4, p 255 (2018)
Volume 10
Issue 4
Chloroquine diphosphate (CQ) is a hydrophilic drug with low entrapment efficiency in hydrophobic nanoparticles (NP). Herpes simplex virus type 1 (HSV-1) is an enveloped double-stranded DNA virus worldwide known as a common human pathogen. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56c269c93ab14da339511d9bf338390
https://doi.org/10.3390/pharmaceutics10040255
https://doi.org/10.3390/pharmaceutics10040255
Autor:
Aurigena Antunes de Araújo, Gerlane Coelho Bernando Guerra, Maria Galvan, Gerly Anne de Castro Brito, Flavia Q. Pirih, Maria Laura de Souza Lima, Caroline Addison Carvalho Xavier de Medeiros, Emanuell Dos Santos Silva, Arnóbio Antônio da Silva Júnior, Aline de Sousa Barbosa Freitas Pereira, Raul Hernandes Bortolin, Adriana Augusto de Rezende, Raimundo Fernandes de Araújo Júnior
Publikováno v:
International journal of molecular sciences, vol 19, iss 11
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3488 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3488 (2018)
Evidence shows that metformin is an antidiabetic drug, which can exert favorable anti-inflammatory effects and decreased bone loss. The development of nanoparticles for metformin might be useful for increased therapeutic efficacy. The aim of this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df776ac77fb3708f222c0bf9053253b6
https://doi.org/10.3390/ijms19113488
https://doi.org/10.3390/ijms19113488