Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Emanuele Seu"'
Autor:
Alex S. James, Stephanie M. Groman, Karen Feiler, James David Jentsch, Edythe D. London, Robert H. Roth, Steven Tran, Taylor A. Clark, Maverick Crawford, John D. Elsworth, Emanuele Seu, Joanna Lee Burtner, Sandra N. Harpster
Publikováno v:
The Journal of Neuroscience. 34:14443-14454
For >30 years, positron emission tomography (PET) has proven to be a powerful approach for measuring aspects of dopaminergic transmission in the living human brain; this technique has revealed important relationships between dopamine D2-like receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddcbf60e593a5c671726a758fd2b2eb
https://doi.org/10.1523/jneurosci.3037-14.2014
https://doi.org/10.1523/jneurosci.3037-14.2014
Publikováno v:
Neuropsychopharmacology. 35:1797-1806
The tendency for some individuals to partake in high-risk behaviors (eg, substance abuse, gambling, risky sexual activities) is a matter of great public health concern, yet the characteristics and neural bases of this vulnerability are largely unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2623dacedecd147949a27961415fa8f
https://doi.org/10.1038/npp.2010.47
https://doi.org/10.1038/npp.2010.47
Autor:
Emanuele Seu, J. David Jentsch
Publikováno v:
Neuropharmacology. 57:665-672
Administration of stimulant and non-stimulant drugs that inhibit monoamine reuptake is known to improve cognitive and behavioral symptoms of attention deficit hyperactivity disorder (ADHD). Although this may reflect acute actions of these drugs, clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b227ba76675e2722899c11a4c2503933
https://doi.org/10.1016/j.neuropharm.2009.08.007
https://doi.org/10.1016/j.neuropharm.2009.08.007
Publikováno v:
Psychopharmacology, vol 202, iss 1-3
Psychopharmacology
Psychopharmacology
Rationale Poor cognitive control, including reversal learning deficits, has been reported in children with attention deficit hyperactivity disorder, in stimulant-dependent humans, and in animal models of these disorders; these conditions have each be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038d7e53198977c9db5fc16eaa5aea45
https://doi.org/10.1007/s00213-008-1250-4
https://doi.org/10.1007/s00213-008-1250-4
Autor:
Emanuele Seu, Stephanie M. Groman, Alex S. James, Lynn A. Fairbanks, J. David Jentsch, Matthew J. Jorgensen
Publikováno v:
The Journal of Neuroscience. 27:14358-14364
Impulsive behavior and novelty seeking are dimensions of temperament that are behavioral determinants of risk for attention deficit/hyperactivity disorder and its neurocognitive endophenotypes, and variation in the dopamine D4receptor gene (DRD4) exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1571c008baa6949869b3b59de66dda
https://doi.org/10.1523/jneurosci.4508-07.2007
https://doi.org/10.1523/jneurosci.4508-07.2007
Publikováno v:
European Neuropsychopharmacology. 15:283-290
We have evaluated, with the use of vertical microdialysis, the effects of fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) on the increase in serotonin and norepinephrine output elicited in rats prefrontal cortex by exposure to footshock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd9491cfdafd8f8dd05dfe9622ba4f8
https://doi.org/10.1016/j.euroneuro.2004.11.003
https://doi.org/10.1016/j.euroneuro.2004.11.003
Publikováno v:
Biological Psychiatry. 55:477-483
Background Chronic exposure to stressful events precipitates or exacerbates many neuropsychiatric disorders, including depression and schizophrenia. Evidence suggests that treatment with the atypical antipsychotic drugs olanzapine or clozapine result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc84346c1d3be140a3291786197a023
https://doi.org/10.1016/j.biopsych.2003.11.020
https://doi.org/10.1016/j.biopsych.2003.11.020
Publikováno v:
European Journal of Pharmacology. 476:55-61
We have previously shown that long-term treatment of rats with antidepressant drugs that affect the activity of noradrenergic and serotonergic neurons by different mechanisms, inhibits the increase in cortical norepinephrine output induced by stress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e14bf41ae70e7a0f37fd3d7fe282d7
https://doi.org/10.1016/s0014-2999(03)02130-7
https://doi.org/10.1016/s0014-2999(03)02130-7
Autor:
Laura Dazzi, M.Giuseppina Pisu, Giulia Cherchi, Robert H. Purdy, Mariangela Serra, Emanuele Seu, Giovanni Biggio
Publikováno v:
Journal of Neurochemistry. 83:1103-1109
The effect of endogenous 3α-hydroxy-5α-pregnan-20-one (3α,5α-TH PROG) on the modulation of mesocortical dopamine extracellular concentration by ethanol was investigated by microdialysis in rats. Intraperitoneal injection of progesterone (5 mg/kg,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13412b94025d8eae19484c666da39a05
https://doi.org/10.1046/j.1471-4159.2002.01218.x
https://doi.org/10.1046/j.1471-4159.2002.01218.x
Autor:
Luca Pusceddu, Amedeo Pau, Mauro Bitti, Emanuele Seu, Cosimo Altomare, Giuseppe Trapani, Laura Dazzi, Battistina Asproni, Giovanni Biggio, Marilena Melosu, Elisabetta Maciocco, Giuseppe Talani, Fabio Busonero, Riccardo Cerri, Enrico Sanna
Publikováno v:
Journal of Medicinal Chemistry. 45:4655-4668
A series of 18 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-piperazines (1a-r) were designed and synthesized as possible ligands with mixed dopamine (DA) D(2)/serotonin 5-HT(1A) affinity, with the aim of identifying novel compounds with neurochemical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dddbf1e0f2966288db1906fb5d97154
https://doi.org/10.1021/jm020848t
https://doi.org/10.1021/jm020848t