Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Emanuele Porru"'
Autor:
Emanuele Porru, Rossana Comito, Nicolò Interino, Andrea Cerrato, Marco Contoli, Paola Rizzo, Matteo Conti, Gianluca Campo, Savino Spadaro, Cristiana Caliceti, Federico Marini, Anna L. Capriotti, Aldo Laganà, Aldo Roda
Publikováno v:
Cells, Vol 13, Iss 18, p 1576 (2024)
The fight against coronavirus disease 2019 (COVID-19) continues. Since the pandemic’s onset, several biomarkers have been proposed to assess the diagnosis and prognosis of this disease. This research aimed to identify potential disease severity bio
Externí odkaz:
https://doaj.org/article/517a12e2ddf24742851fdde82faa4a37
Autor:
Emanuele Porru, Daniel Scicchitano, Nicolò Interino, Teresa Tavella, Marco Candela, Aldo Roda, Jessica Fiori
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract There is a growing interest in the named “acidic sterolbiome” and in the genetic potential of the gut microbiome (GM) to modify bile acid (BA) structure. Indeed, the qualitative composition of BAs in feces correlates with the bowel micro
Externí odkaz:
https://doaj.org/article/204177e42d78489c8267f81e6af77b92
Autor:
Emanuele Porru, Filomena Piro, Rossana Comito, Anastasiia Mosendz, Elirosa Minniti, Matteo Conti, Alessandra Stancari, Francesco Saverio Violante
Publikováno v:
Separations, Vol 10, Iss 9, p 517 (2023)
Idebenone (IDB) (2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone) is a compound synthesized in the early 1980s. Initially developed for the treatment of cognitive disturbances and Alzheimer’s disease, IDB is now studied for Friedreich
Externí odkaz:
https://doaj.org/article/5d4b921cb0c14d529dcfa57b9f5fc9f7
Autor:
Rossana Comito, Emanuele Porru, Nicolò Interino, Matteo Conti, Rossella Terragni, Roberto Gotti, Marco Candela, Patrizia Simoni, Aldo Roda, Jessica Fiori
Publikováno v:
Metabolites, Vol 13, Iss 9, p 980 (2023)
Bile acids (BAs), endogenous acidic steroids synthetized from cholesterol in the liver, play a key role in the gut–liver axis physiopathology, including in hepatotoxicity, intestinal inflammatory processes, and cholesterol homeostasis. Faecal Oxo-B
Externí odkaz:
https://doaj.org/article/a6f3a79864954ad3bda28dac229ef1d0
Autor:
Emanuele Porru, Enrico Giorgi, Silvia Turroni, Riccardo Helg, Michele Silani, Marco Candela, Jessica Fiori, Aldo Roda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Small organic molecules, lipids, proteins, and DNA fragments can remain stable over centuries. Powerful and sensitive chemical analysis can therefore be used to characterize ancient remains for classical archaeological studies. This bio-ecol
Externí odkaz:
https://doaj.org/article/53dea459de8349f6bbf137db19c4aff1
Autor:
Emanuele Porru, Erik Edström, Lisa Arvidsson, Adrian Elmi-Terander, Alexander Fletcher-Sandersjöö, Anita Lövgren Sandblom, Magnus Hansson, Frida Duell, Ingemar Björkhem
Publikováno v:
Brain Sciences, Vol 12, Iss 11, p 1450 (2022)
Idiopathic normal pressure hydrocephalus (iNPH) is the most common form of hydrocephalus in the adult population, and is often treated with cerebrospinal fluid (CSF) drainage using a ventriculoperitoneal (VP) shunt. Symptoms of iNPH include gait impa
Externí odkaz:
https://doaj.org/article/61c367d9fb9949ba8ba68eaec67e7e71
Autor:
Marica Cariello, Roberta Zerlotin, Emanuela Pasculli, Elena Piccinin, Claudia Peres, Emanuele Porru, Aldo Roda, Raffaella Maria Gadaleta, Antonio Moschetta
Publikováno v:
Cancers, Vol 14, Iss 13, p 3081 (2022)
The Farnesoid X Receptor (FXR) is the master regulator of Bile Acids (BA) homeostasis orchestrating their synthesis, transport and metabolism. Disruption of BA regulation has been linked to gut-liver axis diseases such as colorectal cancer (CRC). In
Externí odkaz:
https://doaj.org/article/f506277605474a699db46b87f5165ecd
Autor:
Luisa Marracino, Angela Punzo, Paolo Severi, Rosane Nganwouo Tchoutang, Celia Vargas-De-la-Cruz, Francesca Fortini, Francesco Vieceli Dalla Sega, Alessia Silla, Emanuele Porru, Patrizia Simoni, Valentina Rosta, Alessandro Trentini, Achille Wilfred Ouambo Talla, Silvana Hrelia, Carlo Cervellati, Paola Rizzo, Cristiana Caliceti
Publikováno v:
Nutrients, Vol 14, Iss 8, p 1560 (2022)
Accumulating evidence suggests that high consumption of natural antioxidants promotes health by reducing oxidative stress and, thus, the risk of developing cardiovascular diseases. Similarly, fermentation of natural compounds with lactic acid bacteri
Externí odkaz:
https://doaj.org/article/62b316d046fc49b2a78d8652d48af4a3
Autor:
Raffaella Maria Gadaleta, Oihane Garcia-Irigoyen, Marica Cariello, Natasha Scialpi, Claudia Peres, Stefania Vetrano, Gionatha Fiorino, Silvio Danese, Brian Ko, Jian Luo, Emanuele Porru, Aldo Roda, Carlo Sabbá, Antonio Moschetta
Publikováno v:
EBioMedicine, Vol 57, Iss , Pp 102873- (2020)
Externí odkaz:
https://doaj.org/article/45a648545eec440587640640c1f66604
Autor:
Raffaella Maria Gadaleta, Oihane Garcia-Irigoyen, Marica Cariello, Natasha Scialpi, Claudia Peres, Stefania Vetrano, Gionatha Fiorino, Silvio Danese, Brian Ko, Jian Luo, Emanuele Porru, Aldo Roda, Carlo Sabbà, Antonio Moschetta
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Background: Disruption of bile acid (BA) homeostasis plays a key role in intestinal inflammation. The gut-liver axis is the main site for the regulation of BA synthesis and BA pool size via the combined action of the nuclear Farnesoid X Receptor (FXR
Externí odkaz:
https://doaj.org/article/e28babca9313443181f32d05edf3f235