Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Emanuele Giurisato"'
Autor:
Caterina Tomassetti, Gaia Insinga, Francesca Gimigliano, Andrea Morrione, Antonio Giordano, Emanuele Giurisato
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2381 (2024)
The colony-stimulating factor 1 receptor (CSF-1R) plays a pivotal role in orchestrating cellular interactions within the tumor microenvironment (TME). Although the CSF-1R has been extensively studied in myeloid cells, the expression of this receptor
Externí odkaz:
https://doaj.org/article/e6cb7bb6e9334cbc9f48bedb046f596a
Autor:
Serena Filiberti, Mariapia Russo, Silvia Lonardi, Mattia Bugatti, William Vermi, Cathy Tournier, Emanuele Giurisato
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2709 (2022)
Macrophages are the most abundant immune cells of the tumor microenvironment (TME) and have multiple important functions in cancer. During tumor growth, both tissue-resident macrophages and newly recruited monocyte-derived macrophages can give rise t
Externí odkaz:
https://doaj.org/article/24bf8946a3584d7cb4f9bf73b1b876a9
Autor:
Francesca Consoli, Gianluca Barbieri, Matteo Picciolini, Daniela Medicina, Mattia Bugatti, Valeria Tovazzi, Barbara Liserre, Claudia Zambelli, Fausto Zorzi, Alfredo Berruti, Emanuele Giurisato, William Vermi
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BRAF is one of the most common mutated kinases detected in human cancer, particularly in cases of primary cutaneous melanomas (PCM). Mutations of the BRAF proto-oncogene, at the p.V600 codon, has been detected in more than 50% of primary and metastat
Externí odkaz:
https://doaj.org/article/f5b100756198473aae1bbf616ca50f6f
Autor:
Luca Gambini, Luca Rizzi, Alessandro Pedretti, Orazio Taglialatela-Scafati, Mario Carucci, Andrea Pancotti, Corinna Galli, Martin Read, Emanuele Giurisato, Sergio Romeo, Ilaria Russo
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146627 (2016)
Externí odkaz:
https://doaj.org/article/f3366110125941fd81a275477631c9a4
Autor:
Luca Gambini, Luca Rizzi, Alessandro Pedretti, Orazio Taglialatela-Scafati, Mario Carucci, Andrea Pancotti, Corinna Galli, Martin Read, Emanuele Giurisato, Sergio Romeo, Ilaria Russo
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142509 (2015)
Malaria is an infectious disease caused by Plasmodium parasites. It results in an annual death-toll of ~ 600,000. Resistance to all medications currently in use exists, and novel antimalarial drugs are urgently needed. Plasmepsin V (PmV) is an essent
Externí odkaz:
https://doaj.org/article/c96004415dd74cb1a92c16676b675106
Autor:
Vermi, Mauro Giacomelli, Matilde Monti, Diego Cesare Pezzola, Silvia Lonardi, Mattia Bugatti, Francesco Missale, Rossella Cioncada, Laura Melocchi, Viviana Giustini, Vincenzo Villanacci, Carla Baronchelli, Stefania Manenti, Luisa Imberti, Emanuele Giurisato, William
Publikováno v:
Cancers; Volume 15; Issue 12; Pages: 3097
Colorectal carcinoma (CRC) represents a lethal disease with heterogeneous outcomes. Only patients with mismatch repair (MMR) deficient CRC showing microsatellite instability and hyper-mutated tumors can obtain clinical benefits from current immune ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::175c73b157955ca79569085d2c292a13
Autor:
Mauro Giacomelli, Matilde Monti, Diego Cesare Pezzola, Silvia Lonardi, Mattia Bugatti, Francesco Missale, Rossella Cioncada, Laura Melocchi, Viviana Giustini, Vincenzo Villanacci, Carla Baronchelli, Stefania Manenti, Luisa Imberti, Emanuele Giurisato, William Vermi
CRCMSS/pMMR contain a significantly increased fraction of TREM2+ macrophages (TAMs) and CD66+ neutrophils (TANs) together with decrease of CD4-CD8-CD3+ double negative T lymphocytes (DNTs); no differences were revealed by the analysis of myeloid and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59a9c12c04757c4a8299b8143ca128b6
https://doi.org/10.20944/preprints202305.0526.v1
https://doi.org/10.20944/preprints202305.0526.v1
Autor:
Cathy Tournier, Alan J. Whitmarsh, Emanuele Giurisato, Michael J. Cross, Katherine G. Finegan, Blanca Risa-Ebrí, Nathanael S. Gray, Jinhua Wang, Shiyang Li, Fuhui Chen, Wei Zhang, Qiuping Xu, Karmern Kan, Nisha Ali, Brian A. Telfer, Nitin Sabherwal, Adam J. Pearson, Jingwei Zhang
AX-15836 and BIX-02189 reproduce the inhibitory effect of JWG-045 on the level of phospho-RB and MDA-MB-361 cell density.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44daef79f32aea62873262465322846f
https://doi.org/10.1158/2767-9764.22544282.v1
https://doi.org/10.1158/2767-9764.22544282.v1
Autor:
Cathy Tournier, Alan J. Whitmarsh, Emanuele Giurisato, Michael J. Cross, Katherine G. Finegan, Blanca Risa-Ebrí, Nathanael S. Gray, Jinhua Wang, Shiyang Li, Fuhui Chen, Wei Zhang, Qiuping Xu, Karmern Kan, Nisha Ali, Brian A. Telfer, Nitin Sabherwal, Adam J. Pearson, Jingwei Zhang
Targeting HER2 has become a landmark in the treatment of HER2-driven breast cancer. Nonetheless, the clinical efficacy of anti-HER2 therapies can be short-lived and a significant proportion of patients ultimately develop metastatic disease and die. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f4ef5321e6a190602a2d6eeb8a058f
https://doi.org/10.1158/2767-9764.c.6550601.v1
https://doi.org/10.1158/2767-9764.c.6550601.v1
Autor:
Fabio Facchetti, Stefano Pileri, Giulio Rossi, Antonio Marchetti, Claudio Doglioni, Wilma Pellegrini, Silvano Sozzani, Daniela Bosisio, Daniela Medicina, Elisa Rossi, Piera Balzarini, Silvia Lonardi, Emanuele Giurisato, William Vermi
MEK inhibition blocks FDC-S cell growth in a dose-dependent manner.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b817c3fc62dba3047a73d753cd8c7ed
https://doi.org/10.1158/1078-0432.22451748.v1
https://doi.org/10.1158/1078-0432.22451748.v1