Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Emanuele Andreano"'
Autor:
Fabiola Vacca, Dario Cardamone, Emanuele Andreano, Duccio Medini, Rino Rappuoli, Claudia Sala
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Antimicrobial resistance (AMR) is nowadays a global health concern as bacterial pathogens are increasingly developing resistance to antibiotics. Monoclonal antibodies (mAbs) represent a powerful tool for addressing AMR thanks to their high s
Externí odkaz:
https://doaj.org/article/c6d3d60736d248f3a21ffb09fcea915a
Autor:
Martina Severa, Marilena Paola Etna, Emanuele Andreano, Daniela Ricci, Giada Cairo, Stefano Fiore, Andrea Canitano, Andrea Cara, Paola Stefanelli, Rino Rappuoli, Anna Teresa Palamara, Eliana Marina Coccia
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109703- (2024)
Summary: Monoclonal antibodies (mAb) targeting the SARS-CoV-2 Spike (S) glycoprotein have been exploited for the treatment of severe COVID-19. In this study, we evaluated the immune-regulatory features of two neutralizing anti-S mAbs (nAbs), named J0
Externí odkaz:
https://doaj.org/article/36527309821042d4bfdb8dadf3e37891
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giuseppe Maccari, Giada Antonelli, Valentina Abbiento, Piero Pileri, Linda Benincasa, Ginevra Giglioli, Giulia Piccini, Concetta De Santi, Claudia Sala, Duccio Medini, Emanuele Montomoli, Piet Maes, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Omicron strains of SARS-CoV-2 have displayed high transmissibility and immunological escape to antibody responses derived from natural infection and vaccination. Here the authors compare the antibody response to vaccination and natural infection, ass
Externí odkaz:
https://doaj.org/article/4dbdad3909b344fe846162d4999f1efb
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Valentina Abbiento, Giada Antonelli, Piero Pileri, Noemi Manganaro, Elisa Pantano, Giuseppe Maccari, Silvia Marchese, Lorena Donnici, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Concetta De Santi, Massimiliano Fabbiani, Ilaria Rancan, Mario Tumbarello, Francesca Montagnani, Claudia Sala, Duccio Medini, Raffaele De Francesco, Emanuele Montomoli, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
SARS-CoV-2 vaccines and infection induce antibody responses but the evolution of subsequent variants has resulted in the development of escape mutants. Here the authors characterise, at single cell level, the antibody response in donors after a third
Externí odkaz:
https://doaj.org/article/8bf9f127c9594148a4055cebaa03c05d
Autor:
Claudia Maria Trombetta, Giulia Piccini, Giulio Pierleoni, Margherita Leonardi, Francesca Dapporto, Serena Marchi, Emanuele Andreano, Ida Paciello, Linda Benincasa, Piero Lovreglio, Nicola Buonvino, Nicola Decaro, Angela Stufano, Eleonora Lorusso, Emilio Bombardieri, Antonella Ruello, Simonetta Viviani, Rino Rappuoli, Eleonora Molesti, Alessandro Manenti, Emanuele Montomoli
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-7 (2022)
Antibodies elicited by a triple homologous or heterologous vaccination regimen or following natural SARS-CoV-2 infection combined with a two-dose vaccine course, result in highest neutralization capacity against the Omicron variant BA.1.
Externí odkaz:
https://doaj.org/article/22dc1780e6074a58abad0c8625feb6f3
Autor:
Samuele Stazzoni, Marco Troisi, Valentina Abbiento, Claudia Sala, Emanuele Andreano, Rino Rappuoli
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Neisseria gonorrhoeae (gonococcus) is an obligate human pathogen and the etiological agent of the sexually transmitted disease gonorrhea. The rapid rise in gonococcal resistance to all currently available antimicrobials has become a significant publi
Externí odkaz:
https://doaj.org/article/a0c974db7e94420bb66e994d5f7db92d
Autor:
Emanuele Andreano, Ida Paciello, Silvia Marchese, Lorena Donnici, Giulio Pierleoni, Giulia Piccini, Noemi Manganaro, Elisa Pantano, Valentina Abbiento, Piero Pileri, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Piet Maes, Concetta De Santi, Claudia Sala, Emanuele Montomoli, Raffaele De Francesco, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Here, Andreano and Paciello et al. show, at single cell level, the functional and genetic characteristics underlying the Omicron BA.1 and BA.2 cross-protective antibody response in naïve and previously infected COVID-19 vaccinees.
Externí odkaz:
https://doaj.org/article/f6ef68614439432b9c2c0fa9a78d436d
Autor:
Simone Lanini, Stefano Milleri, Emanuele Andreano, Sarah Nosari, Ida Paciello, Giulia Piccini, Alessandra Gentili, Adhuna Phogat, Inesa Hyseni, Margherita Leonardi, Alessandro Torelli, Emanuele Montomoli, Andrea Paolini, Andrea Frosini, Andrea Antinori, Emanuele Nicastri, Enrico Girardi, Maria Maddalena Plazzi, Giuseppe Ippolito, Francesco Vaia, Giovanni Della Cioppa, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Monoclonal antibodies (mAbs) are a potential therapeutic option for treatment of COVID-19. Here, the authors report safety and pharmacokinetics of an intramuscularly injected mAb (MAD0004J08) during the first 30 days of a phase 1 clinical study.
Externí odkaz:
https://doaj.org/article/ff31551f2ed84fde9583742f1013a74b
Autor:
Marco Troisi, Eleonora Marini, Valentina Abbiento, Samuele Stazzoni, Emanuele Andreano, Rino Rappuoli
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Antimicrobial resistance (AMR) is a quickly advancing threat for human health worldwide and almost 5 million deaths are already attributable to this phenomenon every year. Since antibiotics are failing to treat AMR-bacteria, new tools are needed, and
Externí odkaz:
https://doaj.org/article/ca91b9b359d94e90806e2ec34a284e68
Autor:
Francesca Dapporto, Margherita Leonardi, Claudia Maria Trombetta, Claudia Semplici, Pietro Piu, Giulia Piccini, Linda Benincasa, Serena Marchi, Emanuele Andreano, Piero Lovreglio, Nicola Buonvino, Nicola Decaro, Angela Stufano, Eleonora Lorusso, Emilio Bombardieri, Antonella Ruello, Simonetta Viviani, Rino Rappuoli, Eleonora Molesti, Alessandro Manenti, Emanuele Montomoli
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 6 (2022)
The rapid replacement of Omicron BA.1 by BA.2 sublineage is very alarming, raising the question of whether BA.2 can escape the immunity acquired after BA.1 infection. We compared the neutralizing activity toward the Omicron BA.1 and BA.2 sub-lineages
Externí odkaz:
https://doaj.org/article/b4df1a93eadd4d37a6e9c0ff76288005