Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Emanuela Scacheri"'
Autor:
Antonella Isacchi, Vladimir Lazar, Jean-Charles Soria, Thierry De Baere, Enrico Pesenti, Arturo Galvani, Angela Scaburri, Emanuela Scacheri, Matteo Bertolotti, Francesco Fiorentini, Ciro Mercurio, Raffaele Calogero, Maria G. Brasca, Marina Ciomei, Roberta Bosotti, Giuseppe Locatelli
Supplementary Data from Transcriptional Analysis of an E2F Gene Signature as a Biomarker of Activity of the Cyclin-Dependent Kinase Inhibitor PHA-793887 in Tumor and Skin Biopsies from a Phase I Clinical Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaba6be73dfbb011632dd2d78002c687
https://doi.org/10.1158/1535-7163.22485305
https://doi.org/10.1158/1535-7163.22485305
Autor:
Antonella Isacchi, Vladimir Lazar, Jean-Charles Soria, Thierry De Baere, Enrico Pesenti, Arturo Galvani, Angela Scaburri, Emanuela Scacheri, Matteo Bertolotti, Francesco Fiorentini, Ciro Mercurio, Raffaele Calogero, Maria G. Brasca, Marina Ciomei, Roberta Bosotti, Giuseppe Locatelli
A transcriptional signature of the pan–cyclin-dependent kinase (Cdk) inhibitor PHA-793887 was evaluated as a potential pharmacodynamic and/or response biomarker in tumor and skin biopsies from patients treated in a phase I clinical study. We first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e66bf310a8c93a884d8fde5300ab540
https://doi.org/10.1158/1535-7163.c.6531887
https://doi.org/10.1158/1535-7163.c.6531887
Autor:
Arturo Galvani, Nadia Amboldi, Fabio Gasparri, Antonella Isacchi, G Ukmar, Alessio Somaschini, Antonella Landonio, Angelo Nuzzo, Emanuela Scacheri, Dario Ballinari, Jan Malyszko, Laura Raddrizzani, Roberta Bosotti
Publikováno v:
Genetic Testing and Molecular Biomarkers. 17:254-259
The generation of biological data on wide panels of tumor cell lines is recognized as a valid contribution to the cancer research community. However, research laboratories can benefit from this knowledge only after the identity of each individual cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce307b32447ac3d9d9ffa8aa0097a59
https://doi.org/10.1089/gtmb.2012.0359
https://doi.org/10.1089/gtmb.2012.0359
Autor:
Arturo Galvani, Ciro Mercurio, Enrico Pesenti, Jean-Charles Soria, Vladimir Lazar, Thierry de Baere, Matteo Bertolotti, Antonella Isacchi, Francesco Fiorentini, Angela Scaburri, Raffaele A. Calogero, Roberta Bosotti, Emanuela Scacheri, Maria Gabriella Brasca, Giuseppe Locatelli, Marina Ciomei
Publikováno v:
Molecular Cancer Therapeutics. 9:1265-1273
A transcriptional signature of the pan–cyclin-dependent kinase (Cdk) inhibitor PHA-793887 was evaluated as a potential pharmacodynamic and/or response biomarker in tumor and skin biopsies from patients treated in a phase I clinical study. We first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2e5f9ab4186763e82fdf50cc1fbcf6
https://doi.org/10.1158/1535-7163.mct-09-1163
https://doi.org/10.1158/1535-7163.mct-09-1163
Autor:
Vincenzo Belcastro, Loredana Murino, Roberto Tagliaferri, Pratibha Mithbaokar, Diego di Bernardo, Francesco Iorio, Antonella Isacchi, Rosa Ferriero, Roberta Bosotti, Nicola Brunetti-Pierri, Emanuela Scacheri
A bottleneck in drug discovery is the identification of the molecular targets of a compound (mode of action, MoA) and of its off-target effects. Previous approaches to elucidate drug MoA include analysis of chemical structures, transcriptional respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5ebb4e4dd4b09e3634103b0cd1243f
http://hdl.handle.net/11588/404409
http://hdl.handle.net/11588/404409
Autor:
Emanuela Scacheri, P de Taxis du Poet, Paolo Sarmientos, B Valsasina, Giampaolo Nitti, Luca Benatti
Publikováno v:
Blood Coagulation & Fibrinolysis. 2:113-120
Recombinant DNA technologies now allow the preparation of virtually any polypeptide sequence. Very efficient expression systems for prokaryotic and eukaryotic cells have been developed which may yield large quantities of the desired protein. Bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f38f00fce0d35b0ddb06c4aceed88f
https://doi.org/10.1097/00001721-199102000-00018
https://doi.org/10.1097/00001721-199102000-00018
Autor:
Sandra Healy, Giuseppe Locatelli, Emanuela Scacheri, Luca Sartori, Antonella Isacchi, Roberta Bosotti, Ciro Mercurio, Raffaele A. Calogero
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 8, Iss Suppl 1, p S5 (2007)
BMC Bioinformatics, Vol 8, Iss Suppl 1, p S5 (2007)
Background Microarrays have been widely used for the analysis of gene expression and several commercial platforms are available. The combined use of multiple platforms can overcome the inherent biases of each approach, and may represent an alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fe43b80f1564b1dc7b6c62f54f7fb4
http://hdl.handle.net/2318/35919
http://hdl.handle.net/2318/35919
Autor:
Dario Ballinari, Nadia Amboldi, G Ukmar, Roberta Bosotti, Antonella Isacchi, Alessio Somaschini, Emanuela Scacheri, Angelo Nuzzo
Publikováno v:
EMBnet.journal. 18:77
Motivations. Tumor cell lines are widely used as in vitro models and as screening tools in cancer research. A significant portion of cell lines have been reported to be misidentified, potentially generating misleading data interpretation. Correct ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1614a33ae15c96a4bf257213793e933f
https://doi.org/10.14806/ej.18.a.419
https://doi.org/10.14806/ej.18.a.419
Autor:
Angelo Nuzzo, G Ukmar, Laura Raddrizzani, Antonella Isacchi, Alessio Somaschini, Emanuela Scacheri, Giulia Masetti, Roberta Bosotti, J Malysko
Publikováno v:
EMBnet.journal. 18:79
Motivations. Cell line misidentification is a critical issue in molecular experiments that use normal and/or tumor cell lines as tools for disease characterization and pharmaceutical treatments. Thus, confirmation of cell line genetic identities is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8fec3ba58096b0ce2d30c0d5246b6f
https://doi.org/10.14806/ej.18.a.420
https://doi.org/10.14806/ej.18.a.420
Autor:
Roy T. Sawyer, Barbara Valsasina, Carlo Visco, Emanuela Scacheri, Monica Ferrera, Gaetano Orsini, Gianpaolo Nitti, Paolo Sarmientos
Publikováno v:
European journal of biochemistry. 214(1)
Novel hirudin variants isolated from the leech Hirudinaria manillensis, a leech more specialized for mammalian parasitism, are described. Isolation of antithrombin polypeptides was performed by ion-exchange chromatographies followed by an affinity ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0486c3c4b766ca565a209f9c8daa22ce
https://pubmed.ncbi.nlm.nih.gov/7685281
https://pubmed.ncbi.nlm.nih.gov/7685281