Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Emanuela Porrello"'
Autor:
Cristina Rivellini, Emanuela Porrello, Giorgia Dina, Simona Mrakic-Sposta, Alessandra Vezzoli, Marco Bacigaluppi, Giorgia Serena Gullotta, Linda Chaabane, Letizia Leocani, Silvia Marenna, Emanuela Colombo, Cinthia Farina, Jia Newcombe, Klaus-Armin Nave, Ruggero Pardi, Angelo Quattrini, Stefano C. Previtali
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
Oligodendrocytes are the primary target of demyelinating disorders, and progressive neurodegenerative changes may evolve in the CNS. DNA damage and oxidative stress are considered key pathogenic events, but the underlying molecular mechanisms remain
Externí odkaz:
https://doaj.org/article/a2d1294778d64ffa80a0437adb09bfc7
Autor:
Cristina Rivellini, Giorgia Dina, Emanuela Porrello, Federica Cerri, Marina Scarlato, Teuta Domi, Daniela Ungaro, Ubaldo Del Carro, Alessandra Bolino, Angelo Quattrini, Giancarlo Comi, Stefano C Previtali
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32059 (2012)
Remodeling of extracellular matrix (ECM) is a critical step in peripheral nerve regeneration. In fact, in human neuropathies, endoneurial ECM enriched in fibrin and vitronectin associates with poor regeneration and worse clinical prognosis. According
Externí odkaz:
https://doaj.org/article/0c9589ee107d4f678178467b3e89d746
Autor:
Judith R. Reinhard, Emanuela Porrello, Shuo Lin, Pawel Pelczar, Stefano C. Previtali, Markus A. Rüegg
LAMA2-related muscular dystrophy (LAMA2 MD or MDC1A) is a devastating congenital muscular dystrophy that is caused by mutations in the LAMA2 gene encoding laminin-α2, the long chain of several heterotrimeric laminins. Laminins are essential componen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c80461843f56a3dc75785f11e4f9d6
https://edoc.unibas.ch/88601/
https://edoc.unibas.ch/88601/
Autor:
Cristina Rivellini, Emanuela Porrello, Giorgia Dina, Simona Mrakic-Sposta, 211 Alessandra Vezzoli, Marco Bacigaluppi, Giorgia Serena Gullotta, Linda 1, 3 1, 4 1 1 Chaabane, Letizia Leocani, Silvia Marenna, Emanuela Colombo, Cinthia 2567 Farina, Jia Newcombe, Klaus-Armin Nave, Ruggero Pardi, Angelo 11 Quattrini, Stefano Carlo Previtali
Oligodendrocytes are the primary target of demyelinating disorders and progressive neurodegenerative changes may evolve in the CNS. DNA damage and oxidative stress are considered key pathogenic events, but the underlying molecular mechanisms remain u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10495::11c301ba38750c8e285d82ebf3081f95
Autor:
Stefano C. Previtali, Teuta Domi, Daniela Triolo, Emanuela Porrello, Cristina Rivellini, Federica Cerri, Rosa La Marca, Angelo Quattrini, Giorgia Dina, Alessandra Bolino, Ilaria Vaccari, Carla Taveggia
Publikováno v:
Development. 139:1359-1367
Myelination is a complex process that requires coordinated Schwann cell-axon interactions during development and regeneration. Positive and negative regulators of myelination have been recently described, and can belong either to Schwann cells or neu
Autor:
Emanuela Porrello, Stefano C. Previtali, I. Lorenzetti, D. Goldhamer, Rossana Tonlorenzi, R. Pardi, Daniele Velardo
Publikováno v:
Neuromuscular Disorders. 27:S108
Autor:
A. Guaita, Emanuela Porrello, M. Cairati, Maria Cristina Monti, M. Racchi, S. Govoni, Cristina Montomoli, Elena Sinforiani
Publikováno v:
European Journal of Neurology. 13:639-644
Alzheimer's disease (AD) is a progressive neurodegenerative disease that affects both sexes, with a higher prevalence in women. Declining estrogen levels after menopause may render estrogen target neurons in the brain more susceptible to age or disea
Autor:
Cristina Lanni, Michela Mazzucchelli, Stefano Govoni, Marco Racchi, Emanuela Porrello, S. Carolina Lenzken
Publikováno v:
Chemico-Biological Interactions. :335-338
The events that lead to neurodegeneration in Alzheimer's brains are largely unknown and this fact creates a great challenge for the definition of treatments that may be resolutive for Alzheimer's disease (AD). The current therapeutic option for AD pa
Publikováno v:
Pharmacological Research. 50:441-451
The therapeutic approach for improving the cognitive function in patients with Alzheimer's disease (AD) is mainly based on the potentiation of central cholinergic activity and is achieved clinically by the use of acetylcholinesterase (AChE) inhibitor
Publikováno v:
European Journal of Biochemistry. 271:3068-3075
We investigated the differential role of protein kinase C (PKC) isoforms in the regulated proteolytic release of soluble amyloid precursor protein (sAPPalpha) in SH-SY5Y neuroblastoma cells. We used cells stably transfected with cDNAs encoding either