Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Emanuela Pettinato"'
Autor:
Alessia Brix, Laura Belleri, Alex Pezzotta, Emanuela Pettinato, Mara Mazzola, Matteo Zoccolillo, Anna Marozzi, Rui Monteiro, Filippo Del Bene, Alessandra Mortellaro, Anna Pistocchi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Deficiency of adenosine deaminase 2 (DADA2) is an inborn error of immunity caused by loss-of-function mutations in the adenosine deaminase 2 (ADA2) gene. Clinical manifestations of DADA2 include vasculopathy and immuno-hematological abnormal
Externí odkaz:
https://doaj.org/article/b91819917852418395db5a72ed44b50e
Autor:
Claudia Asperti, Veronica Astro, Emanuela Pettinato, Simona Paris, Angela Bachi, Ivan de Curtis
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20757 (2011)
We have previously identified the scaffold protein liprin-α1 as an important regulator of integrin-mediated cell motility and tumor cell invasion. Liprin-α1 may interact with different proteins, and the functional significance of these interactions
Externí odkaz:
https://doaj.org/article/44f66f669c674c69bab1211f629900e8
Autor:
Cristina Scapin, Cinzia Ferri, Ubaldo Del Carro, Lawrence Wrabetz, Francesca Bianchi, Maurizio D'Antonio, Randal J. Kaufman, Emanuela Pettinato, M. Laura Feltri
Publikováno v:
J Neurosci
Myelin Protein Zero (MPZ/P0) is the most abundant glycoprotein of peripheral nerve myelin. P0 is synthesized by myelinating Schwann cells, processed in the endoplasmic reticulum (ER) and delivered to myelin via the secretory pathway. The mutant P0S63
Autor:
Serena Scala, Federica Barzaghi, Mariasilvia Colantuoni, Emanuela Pettinato, Silvia Gregori, Fabio Benedetti, Francesca Sanvito, Pui Y. Lee, Angelo Lombardo, Andrea Pession, Giulia Milardi, Raisa Jofra Hernandez, Francesca Conti, Luca Basso-Ricci, Simone Cesaro, Luigi Naldini, Francesca Schena, Lucia Sergi Sergi, Paola Capasso, Marco Gattorno, Alessandra Mortellaro, Alessandro Aiuti, Maria Pia Cicalese, Matteo Zoccolillo, Immacolata Brigida
Publikováno v:
Blood Adv
Blood Advances
Blood Advances
Adenosine deaminase 2 deficiency (DADA2) is a rare inherited disorder that is caused by autosomal recessive mutations in the ADA2 gene. Clinical manifestations include early-onset lacunar strokes, vasculitis/vasculopathy, systemic inflammation, immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9e51ee83aa27e05fba92eb6a0c4e39
https://europepmc.org/articles/PMC8405196/
https://europepmc.org/articles/PMC8405196/
Autor:
Ubaldo Del Carro, Desirée Zambroni, Carla Taveggia, Markus H. Schwab, Donatella Caruso, Sophie Belin, Cinzia Ferri, Nico Mitro, Emanuela Pettinato, Lawrence Wrabetz, M. Laura Feltri, Klaus-Armin Nave, Francesca Bianchi, Maurizio D'Antonio, Cristina Scapin, Marta Pellegatta
Publikováno v:
Human Molecular Genetics. 28:992-1006
Charcot-Marie-Tooth (CMT) neuropathies are a group of genetic disorders that affect the peripheral nervous system with heterogeneous pathogenesis and no available treatment. Axonal neuregulin 1 type III (Nrg1TIII) drives peripheral nerve myelination
Autor:
Lawrence Wrabetz, Cristina Scapin, Maurizio Molinari, Francesca Bianchi, Cinzia Ferri, M. Laura Feltri, Maurizio D'Antonio, Emanuela Pettinato, Tatiana Soldà, Vera G. Volpi, Ilaria Fregno, Ubaldo Del Carro
Publikováno v:
PLoS Genetics, 15 (4)
In the peripheral nervous system (PNS) myelinating Schwann cells synthesize large amounts of myelin protein zero (P0) glycoprotein, an abundant component of peripheral nerve myelin. In humans, mutations in P0 cause the demyelinating Charcot-Marie-Too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c938bbad4bf4d0324fb943b63caad72
https://hdl.handle.net/2434/953337
https://hdl.handle.net/2434/953337
Autor:
Emanuela Pettinato, Maria Laura Feltri, Cinzia Ferri, Nico Mitro, Francesca Bianchi, Lawrence Wrabetz, Sophie Belin, Desirée Zambroni, Maurizio D'Antonio, Carla Taveggia, Marta Pellegatta, Cristina Scapin, Ubaldo Del Carro, K.-A. Nave, Donatella Caruso, Markus H. Schwab
Charcot–Marie–Tooth neuropathies (CMTs) are a group of genetic disorders that affect the peripheral nervous system (PNS) with heterogeneous pathogenesis and no available treatment. Axonal Neuregulin 1 type III (Nrg1TIII) drives peripheral nerve m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61dbc71192434c133fdec33721098bf8
https://doi.org/10.1101/386730
https://doi.org/10.1101/386730
Publikováno v:
Experimental Cell Research. 316:915-926
Integrins mediate the interaction between cells and extracellular matrix by assembling adhesive structures that need to be dynamically modulated to allow cell motility. We have recently identified liprin-alpha1 as an essential regulator of integrin d
Autor:
Cinzia Ferri, Samuele Scurati, Enrique Saez, Luis M. Garcia-Segura, Donatella Caruso, Emma De Fabiani, Roberto Cosimo Melcangi, Iñigo Azcoitia, Emanuela Pettinato, Matteo Audano, Silvia Giatti, Maurizio D'Antonio, Nico Mitro, Carla Porretta-Serapiglia, Valentina Alda Carozzi, Maurizio Crestani, Guido Cavaletti, Gaia Cermenati
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Myelin is a membrane characterized by high lipid content to facilitate impulse propagation. Changes in myelin fatty acid (FA) composition have been associated with peripheral neuropathy, but the specific role of peripheral nerve FA synthesis in myeli
Autor:
Ivan de Curtis, Angela Bachi, Emanuela Pettinato, Veronica Astro, Claudia Asperti, Simona Paris
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 6, p e20757 (2011)
PLoS ONE, Vol 6, Iss 6, p e20757 (2011)
We have previously identified the scaffold protein liprin-α1 as an important regulator of integrin-mediated cell motility and tumor cell invasion. Liprin-α1 may interact with different proteins, and the functional significance of these interactions