Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Emanuela M. Bruscia"'
Autor:
Caterina Di Pietro, Ann M. Haberman, Brett D. Lindenbach, Peter C. Smith, Emanuela M. Bruscia, Heather G. Allore, Brent Vander Wyk, Antariksh Tyagi, Caroline J. Zeiss
Publikováno v:
Viruses, Vol 16, Iss 2, p 246 (2024)
Seasonal infection rates of individual viruses are influenced by synergistic or inhibitory interactions between coincident viruses. Endemic patterns of SARS-CoV-2 and influenza infection overlap seasonally in the Northern hemisphere and may be simila
Externí odkaz:
https://doaj.org/article/bf355639ca91449e9e786653ccf5d386
Autor:
Yuanbin Song, Anthony Rongvaux, Ashley Taylor, Tingting Jiang, Toma Tebaldi, Kunthavai Balasubramanian, Arun Bagale, Yunus Kasim Terzi, Rana Gbyli, Xiaman Wang, Xiaoying Fu, Yimeng Gao, Jun Zhao, Nikolai Podoltsev, Mina Xu, Natalia Neparidze, Ellice Wong, Richard Torres, Emanuela M. Bruscia, Yuval Kluger, Markus G. Manz, Richard A. Flavell, Stephanie Halene
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Myelodyplastic hematopoietic stem cells (MDS HSC) have eluded in vivo modeling. Here the authors present a highly efficient MDS patient-derived xenotransplantation model in cytokine-humanized mice with replication of the donors’ genetic complexity
Externí odkaz:
https://doaj.org/article/bcd8edb0cae9459b894b2cf494c1bf39
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
In individuals with cystic fibrosis (CF), lung hyper-inflammation starts early in life and is perpetuated by mucus obstruction and persistent bacterial infections. The continuous tissue damage and scarring caused by non-resolving inflammation leads t
Externí odkaz:
https://doaj.org/article/1394e9f1ace84244952707a40c3f72e1
Publikováno v:
Rossi's Principles of Transfusion Medicine. :642-647
Autor:
Caterina Di Pietro, Hasan H. Öz, Ping-xia Zhang, Ee-chun Cheng, Valentino Martis, Tracey L. Bonfield, Thomas J. Kelley, Ronald Jubin, Abraham Abuchowski, Diane S. Krause, Marie E. Egan, Thomas S. Murray, Emanuela M. Bruscia
Publikováno v:
Experimental & Molecular Medicine. 54:639-652
Overwhelming neutrophilic inflammation is a leading cause of lung damage in many pulmonary diseases, including cystic fibrosis (CF). The heme oxygenase-1 (HO-1)/carbon monoxide (CO) pathway mediates the resolution of inflammation and is defective in
Publikováno v:
Clinics in chest medicine. 43(4)
Cystic fibrosis (CF) pathophysiology is hallmarked by excessive inflammation and the inability to resolve lung infections, contributing to morbidity and eventually mortality. Paradoxically, despite a robust inflammatory response, CF lungs fail to cle
Autor:
Yunjiang Zheng, Esen Sefik, John Astle, Kutay Karatepe, Hasan H. Öz, Angel G. Solis, Ruaidhrí Jackson, Hongbo R. Luo, Emanuela M. Bruscia, Stephanie Halene, Liang Shan, Richard A. Flavell
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
Mice with a functional human immune system serve as an invaluable tool to study the development and function of the human immune system in vivo. A major technological limitation of all current humanized mouse models is the lack of mature and function
Publikováno v:
International journal of molecular sciences. 23(14)
Cystic fibrosis (CF) is caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Chronic inflammation and decline in lung function are major reasons for morbidity in CF. Mutant CFTR expressed in phagocytic cells suc
Autor:
Till Strowig, Richard A. Flavell, Toma Tebaldi, Jonathan Alderman, Jie Chen, Yuanbin Song, Giulia Biancon, Rana Gbyli, Stephanie Halene, Xiaoying Fu, Yimeng Gao, Mina L. Xu, Diane S. Krause, Liang Shan, Wei Liu, Xiaman Wang, Padmavathi Mamillapalli, Amisha Patel, Elizabeth E. Eynon, Ashley Qin, David Urbonas, Emanuela M. Bruscia, David Gonzalez
Publikováno v:
Science
A red-letter day for RBC research The study of primary human red blood cell (huRBC) disorders such as sickle cell disease (SCD) and infectious diseases such as malaria has been hampered by a lack of in vivo models of human erythropoiesis. Song et al.
Autor:
Emanuela M. Bruscia
Publikováno v:
European Respiratory Journal. 61:2300216