Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Emanuela Jacchetti"'
Autor:
Giovanni Buccioli, Carolina Testa, Emanuela Jacchetti, Pietro Pinoli, Stephana Carelli, Stefano Ceri, Manuela T. Raimondi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Statins, widely used cardiovascular drugs that lower cholesterol by inhibiting HMG-CoA reductase, have been increasingly recognized for their potential anticancer properties. This study elucidates the underlying mechanism, revealing that sta
Externí odkaz:
https://doaj.org/article/0c1f53cca6b34826820d8f66486621c7
Autor:
Letizia Messa, Carolina Testa, Stephana Carelli, Federica Rey, Emanuela Jacchetti, Cristina Cereda, Manuela Teresa Raimondi, Stefano Ceri, Pietro Pinoli
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9576 (2024)
The vast corpus of heterogeneous biomedical data stored in databases, ontologies, and terminologies presents a unique opportunity for drug design. Integrating and fusing these sources is essential to develop data representations that can be analyzed
Externí odkaz:
https://doaj.org/article/0a537d4b50914b828990419618625022
Autor:
Claudio Conci, Laura Sironi, Emanuela Jacchetti, Davide Panzeri, Donato Inverso, Rebeca Martínez Vázquez, Roberto Osellame, Maddalena Collini, Giulio Cerullo, Giuseppe Chirico, Manuela Teresa Raimondi
Publikováno v:
APL Bioengineering, Vol 8, Iss 1, Pp 016102-016102-18 (2024)
Tissue histopathology, based on hematoxylin and eosin (H&E) staining of thin tissue slices, is the gold standard for the evaluation of the immune reaction to the implant of a biomaterial. It is based on lengthy and costly procedures that do not allow
Externí odkaz:
https://doaj.org/article/593d26da6d0c4bd88d73d23562431315
Autor:
Francesca Donnaloja, Manuela Teresa Raimondi, Letizia Messa, Bianca Barzaghini, Federica Carnevali, Emanuele Colombo, Davide Mazza, Chiara Martinelli, Lucia Boeri, Federica Rey, Cristina Cereda, Roberto Osellame, Giulio Cerullo, Stephana Carelli, Monica Soncini, Emanuela Jacchetti
Publikováno v:
APL Bioengineering, Vol 7, Iss 3, Pp 036112-036112-21 (2023)
Mechanical stimuli from the extracellular environment affect cell morphology and functionality. Recently, we reported that mesenchymal stem cells (MSCs) grown in a custom-made 3D microscaffold, the Nichoid, are able to express higher levels of stemne
Externí odkaz:
https://doaj.org/article/82830f1396af455493f63e4478316e2c
Autor:
Francesca Donnaloja, Luca Izzo, Marzia Campanile, Simone Perottoni, Lucia Boeri, Francesca Fanizza, Lorenzo Sardelli, Emanuela Jacchetti, Manuela T. Raimondi, Laura Di Rito, Ilaria Craparotta, Marco Bolis, Carmen Giordano, Diego Albani
Publikováno v:
APL Bioengineering, Vol 7, Iss 3, Pp 036117-036117-14 (2023)
We developed an innovative millifluidic organ-on-a-chip device, named MINERVA 2.0, that is optically accessible and suitable to serial connection. In the present work, we evaluated MINERVA 2.0 as millifluidic gut epithelium-on-a-chip by using computa
Externí odkaz:
https://doaj.org/article/95f60ffb30dd4e608a18681b7edbac2e
Autor:
Carolina Testa, Stefania Oliveto, Emanuela Jacchetti, Francesca Donnaloja, Chiara Martinelli, Pietro Pinoli, Roberto Osellame, Giulio Cerullo, Stefano Ceri, Stefano Biffo, Manuela T. Raimondi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2023)
Mesenchymal stem cells (MSCs) are known to be ideal candidates for clinical applications where not only regenerative potential but also immunomodulation ability is fundamental. Over the last years, increasing efforts have been put into the design and
Externí odkaz:
https://doaj.org/article/61df511026d94f78aa09974fe2d1b20b
Autor:
Marta Merli, Lorenzo Sardelli, Nicolò Baranzini, Annalisa Grimaldi, Emanuela Jacchetti, Manuela Teresa Raimondi, Francesco Briatico-Vangosa, Paola Petrini, Marta Tunesi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Introduction: In the view of 3D-bioprinting with cell models representative of neural cells, we produced inks to mimic the basic viscoelastic properties of brain tissue. Moving from the concept that rheology provides useful information to predict ink
Externí odkaz:
https://doaj.org/article/7fbb1dc4e0af40e9adf81c3f66131112
Autor:
Chiara Martinelli, Emanuela Jacchetti
Publikováno v:
Journal of Nanotheranostics, Vol 4, Iss 1, Pp 35-36 (2023)
The application of biocompatible nanomaterials to simultaneously detect and provide treatment of a disease is referred to as nanotheranostics [...]
Externí odkaz:
https://doaj.org/article/7d6d9fff93a7414ba7ad9f99c3b2c0c4
Autor:
Emanuela Jacchetti, Ramin Nasehi, Lucia Boeri, Valentina Parodi, Alessandro Negro, Diego Albani, Roberto Osellame, Giulio Cerullo, Jose Felix Rodriguez Matas, Manuela Teresa Raimondi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Smart biomaterials are increasingly being used to control stem cell fate in vitro by the recapitulation of the native niche microenvironment. By integrating experimental measurements with numerical models, we show that in mesenchymal stem ce
Externí odkaz:
https://doaj.org/article/f506a71168f74e929134b61056b23a77
Autor:
Eveljn Scarian, Matteo Bordoni, Valentina Fantini, Emanuela Jacchetti, Manuela Teresa Raimondi, Luca Diamanti, Stephana Carelli, Cristina Cereda, Orietta Pansarasa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5344 (2022)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease (NDD) that affects motor neurons, causing weakness, muscle atrophy and spasticity. Unfortunately, there are only symptomatic treatments available. Two important innovations in recent
Externí odkaz:
https://doaj.org/article/fd6216ca94a146aeb5cc2fe4529c79e3