Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Emanuela Felley-Bosco"'
Autor:
Ananya Hariharan, Weihong Qi, Hubert Rehrauer, Licun Wu, Manuel Ronner, Martin Wipplinger, Jelena Kresoja‐Rakic, Suna Sun, Lucia Oton‐Gonzalez, Marika Sculco, Véronique Serre‐Beinier, Clément Meiller, Christophe Blanquart, Jean‐François Fonteneau, Bart Vrugt, Jan Hendrik Rüschoff, Isabelle Opitz, Didier Jean, Marc dePerrot, Emanuela Felley‐Bosco
Publikováno v:
Molecular Oncology, Vol 16, Iss 22, Pp 3949-3974 (2022)
We previously observed increased levels of adenosine‐deaminase‐acting‐on‐dsRNA (Adar)‐dependent RNA editing during mesothelioma development in mice exposed to asbestos. The aim of this study was to characterize and assess the role of ADAR
Externí odkaz:
https://doaj.org/article/68417b6aa7474f1b8efa6a6d5df04297
Autor:
Karin D. Prummel, Helena L. Crowell, Susan Nieuwenhuize, Eline C. Brombacher, Stephan Daetwyler, Charlotte Soneson, Jelena Kresoja-Rakic, Agnese Kocere, Manuel Ronner, Alexander Ernst, Zahra Labbaf, David E. Clouthier, Anthony B. Firulli, Héctor Sánchez-Iranzo, Sundar R. Naganathan, Rebecca O’Rourke, Erez Raz, Nadia Mercader, Alexa Burger, Emanuela Felley-Bosco, Jan Huisken, Mark D. Robinson, Christian Mosimann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The mesothelium supports homeostasis and regeneration, yet its development origins remain unclear. Here, the authors uncovered the earliest mesothelium progenitor cells in zebrafish, linking Hand2 gene function to mesothelium formation and its re-act
Externí odkaz:
https://doaj.org/article/445f40166b9345a1905f77ae35cd17f3
Autor:
Suna Sun, MD, Weihong Qi, PhD, Hubert Rehrauer, PhD, Manuel Ronner, Ananya Hariharan, MSc, Martin Wipplinger, MSc, Clément Meiller, Msc, Rolf Stahel, MD, Martin Früh, MD, Ferdinando Cerciello, MD, PhD, Jean-François Fonteneau, PhD, Didier Jean, PhD, Emanuela Felley-Bosco, PhD, PD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 12, Pp 100430- (2022)
Introduction: The aim of this study was to investigate endogenous retrovirus (ERV) expression and type I interferon (IFN) activation in human pleural mesothelioma (PM) and their association with clinical outcome. Methods: The expression of ERV was de
Externí odkaz:
https://doaj.org/article/103818aaa4c24187ae63f2c4ea807f4b
Autor:
Emanuela Felley-Bosco
Publikováno v:
Cancers, Vol 15, Iss 11, p 2969 (2023)
Recent high-throughput RNA sequencing technologies have confirmed that a large part of the non-coding genome is transcribed. The priority for further investigations is nevertheless generally given in cancer to coding sequences, due to the obvious int
Externí odkaz:
https://doaj.org/article/d870faf8bcf441388d100c7fcca22325
Autor:
Alexander Laure, Angelica Rigutto, Michaela B. Kirschner, Lennart Opitz, Linda Grob, Isabelle Opitz, Emanuela Felley-Bosco, Stefanie Hiltbrunner, Alessandra Curioni-Fontecedro
Publikováno v:
Cancers, Vol 15, Iss 10, p 2813 (2023)
Cell lines are extensively used to study cancer biology. However, the use of highly passaged commercial cell lines has to be questioned, as they do not closely resemble the originating tumor. To understand the reliability of preclinical models for Ma
Externí odkaz:
https://doaj.org/article/4d404c809e0b4b83b26f98a5edcdda69
Autor:
Licun Wu, Kosuke Yoshihara, Hana Yun, Saraf Karim, Nastaran Shokri, Fatemeh Zaeimi, H. S. Jeffrey Man, Amin Zia, Emanuela Felley-Bosco, Marc de Perrot
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4264 (2023)
Malignant mesothelioma (MESO) consists of epithelioid, biphasic, and sarcomatoid subtypes with different epithelial–mesenchymal transition (EMT) phenotypes. We previously identified a panel of four MESO EMT genes correlating with an immunosuppressi
Externí odkaz:
https://doaj.org/article/7f6863cb52d4468896a11478dbde7479
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2874 (2023)
Pleural mesothelioma (PM) is a cancer where epithelioid, biphasic and sarcomatoid histotypes are observed. Sarcomatoid PM is characterized by mesenchymal features. Multi-omics have been used to characterize the epithelial-to-mesenchymal (EMT) phenoty
Externí odkaz:
https://doaj.org/article/1d9404287861444c8bb81f8512f9bfd9
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/9ebc0a4d9b19429da7316c0cb7ec55da
Autor:
Costa Bachas, Jasmina Hodzic, Johannes C. van der Mijn, Chantal Stoepker, Henk M. W. Verheul, Rob M. F. Wolthuis, Emanuela Felley-Bosco, Wessel N. van Wieringen, Victor W. van Beusechem, Ruud H. Brakenhoff, Renée X. de Menezes
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Reproducibility of hits from independent CRISPR or siRNA screens is poor. This is partly due to data normalization primarily addressing technical variability within independent screens, and not the technical differences between th
Externí odkaz:
https://doaj.org/article/826f3204ee2b48118fd68b46cacf334f
Publikováno v:
Open Biology, Vol 10, Iss 10 (2020)
RNA editing is a post-transcriptional process increasing transcript diversity, thereby regulating different biological processes. We recently observed that mutations resulting from RNA editing due to hydrolytic deamination of adenosine increase durin
Externí odkaz:
https://doaj.org/article/567a31c95dec4241819b13b80112f277