Galactosylated polymeric carriers for liver targeting of sorafenib

Autor: Emanuela F. Craparo a, Carla Sardo a, Rosa Serio b, Maria G. Zizzo b, Maria L. Bondì c, Gaetano Giammona a, d, Gennara Cavallaro a

Publikováno v: International journal of pharmaceutics
466 (2014): 172–180. doi:10.1016/j.ijpharm.2014.02.047
info:cnr-pdr/source/autori:Emanuela F. Craparo a, Carla Sardo a, Rosa Serio b, Maria G. Zizzo b, Maria L. Bondì c, Gaetano Giammona a,d, Gennara Cavallaro a,*/titolo:Galactosylated polymeric carriers for liver targeting of sorafenib/doi:10.1016%2Fj.ijpharm.2014.02.047/rivista:International journal of pharmaceutics (Print)/anno:2014/pagina_da:172/pagina_a:180/intervallo_pagine:172–180/volume:466

In this paper, we describe the preparation of liver-targeted polymeric micelles potentially able to carry sorafenib to hepatocytes for treatment of hepatocarcinoma (HCC), exploiting the presence of carbohydrate receptors, ASGPR. These micelles were p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd557cfa6767f339331ca7eca0dcfe0b
https://doi.org/10.1016/j.ijpharm.2014.02.047

Production of polymeric micro- and nanostructures with tunable properties as pharmaceutical delivery systems

Autor: Gennara Cavallaro, Salvatore Emanuele Drago, Emanuela Fabiola Craparo, Gaetano Giammona

The production of novel graft copolymers based on poly-e-caprolactone (PCL) and polyaspartamide are useful to realize structures for potential biomedical applications. Here, the synthesis of pegylated PCL/polyhydroxyethyl aspartamide (PHEA) graft cop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1be2e4d24de7fdb9a46f8a30965294
http://hdl.handle.net/10447/423478