Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Emanuela Caci"'
Autor:
Emanuela Pesce, Elvira Sondo, Loretta Ferrera, Valeria Tomati, Emanuela Caci, Paolo Scudieri, Ilaria Musante, Mario Renda, Nesrine Baatallah, Nathalie Servel, Alexandre Hinzpeter, Diego di Bernardo, Nicoletta Pedemonte, Luis J. V. Galietta
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The mutation F508del, responsible for a majority of cystic fibrosis cases, provokes the instability and misfolding of the CFTR chloride channel. Pharmacological recovery of F508del-CFTR may be obtained with small molecules called correctors. However,
Externí odkaz:
https://doaj.org/article/33b3d2667b244736811ea67a047edc53
Autor:
Paolo Scudieri, Ilaria Musante, Arianna Venturini, Daniela Guidone, Michele Genovese, Federico Cresta, Emanuela Caci, Alessandro Palleschi, Marco Poeta, Francesca Santamaria, Fabiana Ciciriello, Vincenzina Lucidi, Luis J. V. Galietta
Publikováno v:
Cells, Vol 9, Iss 9, p 2090 (2020)
The airway epithelium contains ionocytes, a rare cell type with high expression of Forkhead Box I1 (FOXI1) transcription factor and Cystic Fibrosis Transmembrane conductance Regulator (CFTR), a chloride channel that is defective in cystic fibrosis (C
Externí odkaz:
https://doaj.org/article/ee368ab527914c89a92253aca0659915
Autor:
Ambra Gianotti, Valeria Capurro, Livia Delpiano, Marcin Mielczarek, María García-Valverde, Israel Carreira-Barral, Alessandra Ludovico, Michele Fiore, Debora Baroni, Oscar Moran, Roberto Quesada, Emanuela Caci
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1488 (2020)
Cystic fibrosis (CF) is a genetic disease characterized by the lack of cystic fibrosis transmembrane conductance regulator (CFTR) protein expressed in epithelial cells. The resulting defective chloride and bicarbonate secretion and imbalance of the t
Externí odkaz:
https://doaj.org/article/a96bb0e8f790471388e44e5bb7271703
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cystic fibrosis (CF) is a chronic disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, which encodes for a channel expressed at the apical surface of epithelial tissues. Defective chloride and bicarbonate secretion,
Externí odkaz:
https://doaj.org/article/4f2d866368ce419584224b862b32c3b0
Autor:
Claudia Cossu, Michele Fiore, Debora Baroni, Valeria Capurro, Emanuela Caci, Maria Garcia-Valverde, Roberto Quesada, Oscar Moran
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cystic fibrosis (CF) is a genetic lethal disease, originated from the defective function of the CFTR protein, a chloride and bicarbonate permeable transmembrane channel. CF mutations affect CFTR protein through a variety of molecular mechanisms which
Externí odkaz:
https://doaj.org/article/3c93af87f021448d928e0b891a4dc2e9
Autor:
Alessandra Chiappori, Chiara Folli, Francesco Balbi, Emanuela Caci, Anna Maria Riccio, Laura De Ferrari, Giovanni Melioli, Fulvio Braido, Giorgio Walter Canonica
Publikováno v:
World Allergy Organization Journal, Vol 9, Iss , Pp - (2016)
Background Chronic obstructive pulmonary disease (COPD) is a progressive lung disorder characterized by poorly reversible airway obstruction and its pathogenesis remains largely misunderstood. Local changes of regulatory T-cell populations in the lun
Externí odkaz:
https://doaj.org/article/177259ee38934546896d54ab2013abc9
Autor:
Emanuela Caci, Paolo Scudieri, Emma Di Carlo, Patrizia Morelli, Silvia Bruno, Ida De Fino, Alessandra Bragonzi, Ambra Gianotti, Elvira Sondo, Loretta Ferrera, Alessandro Palleschi, Luigi Santambrogio, Roberto Ravazzolo, Luis J V Galietta
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131775 (2015)
Induction of mucus hypersecretion in the airway epithelium by Th2 cytokines is associated with the expression of TMEM16A, a Ca2+-activated Cl- channel. We asked whether exposure of airway epithelial cells to bacterial components, a condition that mim
Externí odkaz:
https://doaj.org/article/d779221725f04b499ed7db0ee4004618
Autor:
Irma Airoldi, Emma Di Carlo, Claudia Cocco, Emanuela Caci, Michele Cilli, Carlo Sorrentino, Gabriella Sozzi, Silvano Ferrini, Sandra Rosini, Giulia Bertolini, Mauro Truini, Francesco Grossi, Luis Juan Vicente Galietta, Domenico Ribatti, Vito Pistoia
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6119 (2009)
BACKGROUND: Non small cell lung cancer (NSCLC) is a leading cause of cancer death. We have shown previously that IL-12rb2 KO mice develop spontaneously lung adenocarcinomas or bronchioalveolar carcinomas. Aim of the study was to investigate i) IL-12R
Externí odkaz:
https://doaj.org/article/fe43b8e1d390408698197619502e6321
Autor:
Agostina Ventura, Mauro Carcheri, Emanuela Caci, Patrizia Caligiuri, Roberto Capuzzo, Ilaria Chiossone, Caterina Oliveri, Paola Milano, Rossana Cirillo, Gianni Tunesi
Publikováno v:
Microbiologia Medica, Vol 21, Iss 4 (2006)
Human Papillomavirus (HPV) infection is the main cause of cervical cancer and cervical intraepithelial neoplasia (CIN) worldwide. Consequently, it would be useful to evaluate HPV testing to screen for cervical cancer. Recently several molecular biolo
Externí odkaz:
https://doaj.org/article/6d2257aefda74d20ad8e0d7159212c1c
Autor:
Alessandra Ghigo, Alessandra Murabito, Valentina Sala, Anna Rita Pisano, Serena Bertolini, Ambra Gianotti, Emanuela Caci, Alessio Montresor, Aiswarya Premchandar, Flora Pirozzi, Kai Ren, Angela Della Sala, Marco Mergiotti, Wito Richter, Eyleen de Poel, Michaela Matthey, Sara Caldrer, Rosa A. Cardone, Federica Civiletti, Andrea Costamagna, Nancy L. Quinney, Cosmin Butnarasu, Sonja Visentin, Maria Rosaria Ruggiero, Simona Baroni, Simonetta Geninatti Crich, Damien Ramel, Muriel Laffargue, Carlo G. Tocchetti, Renzo Levi, Marco Conti, Xiao-Yun Lu, Paola Melotti, Claudio Sorio, Virginia De Rose, Fabrizio Facchinetti, Vito Fanelli, Daniela Wenzel, Bernd K. Fleischmann, Marcus A. Mall, Jeffrey Beekman, Carlo Laudanna, Martina Gentzsch, Gergely L. Lukacs, Nicoletta Pedemonte, Emilio Hirsch
Publikováno v:
Sci Transl Med
Cyclic adenosine 3′,5′-monophosphate (cAMP)–elevating agents, such as β 2 -adrenergic receptor (β 2 -AR) agonists and phosphodiesterase (PDE) inhibitors, remain a mainstay in the treatment of obstructive respiratory diseases, conditions chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7206a5f43dd3588b77ae179d94c0d7
https://pubmed.ncbi.nlm.nih.gov/35353541
https://pubmed.ncbi.nlm.nih.gov/35353541