Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Emanuel Smeds"'
Autor:
Praveen Papareddy, Ines Tapken, Keshia Kroh, Ravi Kiran Varma Bhongir, Milladur Rahman, Maria Baumgarten, Eda Irem Cim, Lilla Györffy, Emanuel Smeds, Ariane Neumann, Srinivas Veerla, Jon Olinder, Henrik Thorlacus, Cecilia Ryden, Eva Bartakova, Michal Holub, Heiko Herwald
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Extracellular vesicles (EVs) play a crucial role in intercellular communication by transferring bioactive molecules from donor to recipient cells. As a result, EV fusion leads to the modulation of cellular functions and has an impact on both
Externí odkaz:
https://doaj.org/article/d617a9779fb94c98ae7a1ceb8541bf60
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Human fetal hemoglobin (HbF) is an attractive starting protein for developing an effective agent for oxygen therapeutics applications. This requires that HbF can be produced in heterologous systems at high levels and in a homogeneous form. The introd
Externí odkaz:
https://doaj.org/article/db916bc918174a538d54a6e486373c90
Autor:
Praveen Papareddy, Gopinath Kasetty, Saud Alyafei, Emanuel Smeds, Outi M. H. Salo-Ahen, Stefan R. Hansson, Arne Egesten, Heiko Herwald
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 724-737 (2018)
Coagulation, complement, and innate immunity are tightly interwoven and form an alliance that can be traced back to early eukaryotic evolution. Here we employed an ecoimmunological approach using Tissue Factor Pathway Inhibitor (TFPI)-1-derived pepti
Externí odkaz:
https://doaj.org/article/6d5ce05ad2624db2ad20d9efd1e4fb86
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Due to its compatible oxygen-transporting abilities, hemoglobin (Hb) is a protein of interest in the development of artificial oxygen therapeutics. Despite continuous formulation attempts, extracellular Hb solution often exhibits undesirable reaction
Externí odkaz:
https://doaj.org/article/5f6e14cddf714e8db7ae475fa6387fba
Autor:
Erik Malmström, Ola Kilsgård, Simon Hauri, Emanuel Smeds, Heiko Herwald, Lars Malmström, Johan Malmström
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Sepsis can lead to multiple organ failure that could potentially be reflected by change in plasma protein abundance. Here the authors describe a proteomics strategy that allows the determination of plasma proteins tissue origin in a quantitative mann
Externí odkaz:
https://doaj.org/article/180515b4471648a094ca8757685ed496
Autor:
Johannes Westman, Praveen Papareddy, Madelene W Dahlgren, Bhavya Chakrakodi, Anna Norrby-Teglund, Emanuel Smeds, Adam Linder, Matthias Mörgelin, Bengt Johansson-Lindbom, Arne Egesten, Heiko Herwald
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005319 (2015)
The innate immune system relies to a great deal on the interaction of pattern recognition receptors with pathogen- or damage-associated molecular pattern molecules. Extracellular histones belong to the latter group and their release has been describe
Externí odkaz:
https://doaj.org/article/75b1a51867ca4011801e8175f081117a
Autor:
Qiong Xue, Sarah A Jenkins, Chunfang Gu, Emanuel Smeds, Qing Liu, Ranga Vasan, Brooke H Russell, Yi Xu
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11665 (2010)
Dissemination of Bacillus anthracis from the respiratory mucosa is a critical step in the establishment of inhalational anthrax. Recent in vitro and in vivo studies indicated that this organism was able to penetrate the lung epithelium by directly en
Externí odkaz:
https://doaj.org/article/70ded28a401246d7b1cc5a5a303c7cc9
Autor:
Vannakambadi K Ganesh, Jose J Rivera, Emanuel Smeds, Ya-Ping Ko, M Gabriela Bowden, Elisabeth R Wann, Shivasankarappa Gurusiddappa, J Ross Fitzgerald, Magnus Höök
Publikováno v:
PLoS Pathogens, Vol 4, Iss 11, p e1000226 (2008)
The fibrinogen (Fg) binding MSCRAMM Clumping factor A (ClfA) from Staphylococcus aureus interacts with the C-terminal region of the fibrinogen (Fg) gamma-chain. ClfA is the major virulence factor responsible for the observed clumping of S. aureus in
Externí odkaz:
https://doaj.org/article/62a81d80729147a18c8ca3cf8635b870
Autor:
Saud Alyafei, Heiko Herwald, Praveen Papareddy, Gopinath Kasetty, Stefan R. Hansson, Outi M. H. Salo-Ahen, Arne Egesten, Emanuel Smeds
Publikováno v:
Virulence
Virulence, Vol 9, Iss 1, Pp 724-737 (2018)
Virulence, Vol 9, Iss 1, Pp 724-737 (2018)
Coagulation, complement, and innate immunity are tightly interwoven and form an alliance that can be traced back to early eukaryotic evolution. Here we employed an ecoimmunological approach using Tissue Factor Pathway Inhibitor (TFPI)-1-derived pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b6d87fde3ee2782db9faad3c1a09d6
Autor:
Madlen Rossnagel, Praveen Papareddy, Gülcan Kilic, Heiko Herwald, Cristina Novembrino, Srinivas Veerla, Femke Doreen Hollwedel, María Eugenia de la Morena-Barrio, Maria Abbattista, Ida Martinelli, Gopinath Kasetty, Andrea Artoni, Javier Corral, Arne Egesten, Irene Martínez-Martínez, Emanuel Smeds, Cord Brakebusch, Adam Linder, Clément Naudin, Johannes Westman
Publikováno v:
Nature Microbiology. 4:2442-2455
Severe infectious diseases are often characterized by an overwhelming and unbalanced systemic immune response to microbial infections. Human antithrombin (hAT) is a crucial coagulation inhibitor with anti-inflammatory activities. Here we identify thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fb5cbbd118ef8208e5cbaf0dda6776
https://doi.org/10.1038/s41564-019-0559-6
https://doi.org/10.1038/s41564-019-0559-6