Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Emanuel Silverstein"'
Autor:
Joan Friedland, Emanuel Silverstein
Publikováno v:
Pharmacology, biochemistry, and behavior. 37(4)
The STR/N inbred mouse is a behavioral mutant that drinks up to four times its body weight in water or normal saline per day when given free access, despite the lack of physiological need. Since angiotensin II (AII) is a powerful elicitor of drinking
Publikováno v:
Journal of Clinical Investigation. 67:1151-1160
To enable its immunohistologic localization, angiotensin converting enzyme (EC 3.4.15.1) from human lung was solubilized by trypsinization and purified approximately 2,660-fold to apparent homogeneity from a washed lung particulate fraction. The spec
Publikováno v:
American Journal of Clinical Pathology. 70:348-351
Serum collagenase was significantly elevated in stage II, but not stage I sarcoidosis, in contrast to elevation of serum angiotensin-converting enzyme in stages I and II. Neither serum collagenase nor angiotensin-converting enzyme was elevated in act
Publikováno v:
Annals of the New York Academy of Sciences. 278:498-513
A statistically highly significant elevation of serum ACE was found in a group of 58 patients with sarcoidosis (serum ACE was elevated in 34% of patients), as compared with normal controls and patients with tuberculosis and various other common disea
Autor:
Joan Friedland, Emanuel Silverstein
Publikováno v:
American Journal of Clinical Pathology. 66:416-424
A simple, rapid, highly sensitive and reproducible assay for angiotensin-converting enzyme in untreated serum is described. It is based on the conversion of the substrate analog, hippuryl-L-histidyl-L-leucine (5 mM in 0.1 M K phosphate, pH 8.3-0.3 M
Publikováno v:
The American Journal of Medicine. 75:233-236
Serum angiotensin-converting enzyme was elevated in patients with hyperthyroidism (72 +/- 31 nmol/minute/ml, n = 12, p less than 0.001) but not in patients with hypothyroidism (38 +/- 3, n = 3) or thyroiditis (26, n = 1), and was positively correlate
Autor:
Joan Friedland, Emanuel Silverstein
Publikováno v:
International Journal of Biochemistry. 15:1337-1343
Rabbit serum, lung and corticosteroid-induced macrophage angiotensin-converting enzymes were compared with respect to migration on polyacrylamide-gel electrophoresis, sucrose gradient centrifugation and Km. Cellular particulate enzymes solubilized by
Autor:
Joan Friedland, Emanuel Silverstein
Publikováno v:
American Journal of Clinical Pathology. 68:225-228
A simple, rapid, highly sensitive and reproducible fluorimetric assay for angiotensin-converting enzyme in untreated serum using the natural substrate based on a similar assay with hippuryl-L-histidine-L-leucine is described. Angiotensin I (0.2 mM in
Publikováno v:
Biochemical and Biophysical Research Communications. 83:843-849
Angiotensin converting enzyme (E.C.3.4.15.1, peptidyl dipeptidase) in circulating human monocytes rose from undetectable or minimal levels in vivo to as high as 35.5 nmol/min·mgprotein (>300-fold increase) after 6 or 7 days in culture. Enzyme induct