Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Emanouil Georgarakis"'
Publikováno v:
Drug Development and Industrial Pharmacy. 40:886-895
This study investigates the solid-solid interactions between nimodipine (NIM) and polyethylene glycol (PEG) of different mean molecular weights (PEG 2000, 4000 and 6000), in solid dispersion systems, applying differential scanning calorimetry (DSC),
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 77:122-131
The present study investigates the use of nimodipine-polyethylene glycol solid dispersions for the development of effervescent controlled release floating tablet formulations. The physical state of the dispersed nimodipine in the polymer matrix was c
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 49:1192-1202
In the present study an isocratic reversed-phase high-performance liquid chromatography was investigated for the separation of nimodipine and impurities (A, B and C) using statistical experimental design. Initially, a full factorial design was used i
Artificial neural networks in the optimization of a nimodipine controlled release tablet formulation
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 74(2)
Artificial neural networks (ANNs) were employed in the optimization of a nimodipine zero-order release matrix tablet formulation, and their efficiency was compared to that of multiple linear regression (MLR) on an external validation set. The amounts
Publikováno v:
Helvetica Chimica Acta. 62:234-270
On the Photochemistry of 1H- and 2H-Indazoles in Acidic Solution It is shown that 1H- and 2H-indazoles (cf. Scheme 2) on protonation (0, 1N H2SO4 in water or alcoholic solution) give analogous indazolium ions (see Fig. 1 and 2) which on irradiation u