Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Eman Y Gohar"'
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95079 (2014)
We investigated the effect of chronic nicotine on cholinergically-mediated renal vasodilations in female rats and its modulation by the nitric oxide synthase (NOS)/heme oxygenase (HO) pathways. Dose-vasodilatory response curves of acetylcholine (0.01
Externí odkaz:
https://doaj.org/article/2458538344614829b809b9dee5fa2f8a
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Introduction Current understanding of sodium (Na+) handling is based on studies done primarily in males. Contrary to the gradual increase in high salt (HS) induced natriuresis over 3–5 days in males, female Sprague Dawley (SD) rats have a
Externí odkaz:
https://doaj.org/article/4d5ff4dcf7274993be822c2f69330dc5
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/badaac1c1eef46b3a347103873f2f815
Autor:
Ginger L. Guthrie, Rawan N. Almutlaq, Sho Sugahara, Maryam K. Butt, Craig R. Brooks, David M. Pollock, Eman Y. Gohar
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Demographic studies reveal lower prevalence of hypertension among premenopausal females compared to age-matched males. The kidney plays a central role in the maintenance of sodium (Na+) homeostasis and consequently blood pressure. Renal endothelin-1
Externí odkaz:
https://doaj.org/article/c0d090084a8a4da78febca32b7df9202
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-10 (2020)
Abstract Background Premenopausal women have a lower risk of hypertension compared to age-matched men and postmenopausal women. P2Y2 and P2Y4 purinoceptor can be considered potential contributors to hypertension due to their emerging roles in regulat
Externí odkaz:
https://doaj.org/article/42ffd62e916c439b97b04d0a3ee6f1e1
Autor:
Eman Y. Gohar, Carmen De Miguel, Ijeoma E. Obi, Elizabeth M. Daugherty, Kelly A. Hyndman, Bryan K. Becker, Chunhua Jin, Randee Sedaka, Jermaine G. Johnston, Pengyuan Liu, Joshua S. Speed, Tanecia Mitchell, Alison J. Kriegel, Jennifer S. Pollock, David M. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined. Here, we determined
Externí odkaz:
https://doaj.org/article/0cb3e71087914936a984fb5185dc2cdf
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-9 (2019)
Abstract Background The pathogenesis of hypertension is distinct between men and women. Endothelin-1 (ET-1) is a potential contributor to sex differences in the pathophysiology of hypertension. ET-1 participates in blood pressure regulation through a
Externí odkaz:
https://doaj.org/article/be7732a1a01a4d75a4a2f6298402d2c5
Autor:
Eman Y. Gohar, Elizabeth M. Daugherty, Jeffrey O. Aceves, Randee Sedaka, Ijeoma E. Obi, J. Miller Allan, Reham H. Soliman, Chunhua Jin, Carmen De Miguel, Sarah H. Lindsey, Jennifer S. Pollock, David M. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 10 (2020)
Background The novel estrogen receptor, G‐protein–coupled estrogen receptor (GPER), is responsible for rapid estrogen signaling. GPER activation elicits cardiovascular and nephroprotective effects against salt‐induced complications, yet there i
Externí odkaz:
https://doaj.org/article/04ff94a8dd55461fb187cedf3a1e54e3
Publikováno v:
Redox Biology, Vol 31, Iss , Pp - (2020)
Sex differences in redox signaling in the kidney present new challenges and opportunities for understanding the physiology and pathophysiology of the kidney. This review will focus on reactive oxygen species, immune-related signaling pathways and end
Externí odkaz:
https://doaj.org/article/d07e1202868d4b80a9214211b484b4fd
Publikováno v:
American Journal of Physiology-Renal Physiology. 323:F349-F360
Aromatase is a monooxygenase that catalyzes the rate-limiting step of estrogen biosynthesis from androgens. Aromatase inhibitors are widely used for the treatment of patients with hormone receptor-positive breast cancer. However, the effects of aroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de726dd202e239bd4fba4af2bcadc46
https://doi.org/10.1152/ajprenal.00055.2022
https://doi.org/10.1152/ajprenal.00055.2022