Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eman H M Mohammed"'
Autor:
Shaima A. El-Mowafi, Anastasia G. Konshina, Eman H. M. Mohammed, Nikolay A. Krylov, Roman G. Efremov, Keykavous Parang
Publikováno v:
Molecules, Vol 28, Iss 24, p 8049 (2023)
In our ongoing quest to design effective antimicrobial peptides (AMPs), this study aimed to elucidate the mechanisms governing cyclic amphiphilic AMPs and their interactions with membranes. The objective was to discern the nature of these interaction
Externí odkaz:
https://doaj.org/article/4b70d63ae20e4b2db7dd629c475de2aa
Autor:
Hazem E. Elsersy, Magdy A. H. Zahran, Abd-Elazeem Elbakry, Mohamed Abd-Elwahab, Mohamed Milegy Ahmed, Mohamed Salah Elgandy, Eman H. M. Mohammed, Nourhan M. Elewa
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The COVID-19 pandemic is still posing challenging health and economic problems. Effective broad-spectrum antiviral therapy is urgently needed for the control of early SARS-CoV-2 infection to limit its spread and mutations. In this randomized placebo-
Externí odkaz:
https://doaj.org/article/e6482c7d31784613ad5614e788ec4201
Autor:
Joanna Bojarska, Adam Mieczkowski, Zyta M. Ziora, Mariusz Skwarczynski, Istvan Toth, Ahmed O. Shalash, Keykavous Parang, Shaima A. El-Mowafi, Eman H. M. Mohammed, Sherif Elnagdy, Maha AlKhazindar, Wojciech M. Wolf
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1515 (2021)
Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of peptides widespread in nature, are unsurpassed in their structural and bio-functional diversity. DKPs, especially those containing proline, due to their unique feat
Externí odkaz:
https://doaj.org/article/d279de362a2e4c96bbfe79128766cb7f
Autor:
Eman H. M. Mohammed, Dindyal Mandal, Saghar Mozaffari, Magdy Abdel-Hamied Zahran, Amany Mostafa Osman, Rakesh Kumar Tiwari, Keykavous Parang
Publikováno v:
Molecules, Vol 25, Iss 11, p 2581 (2020)
We have previously reported cyclic cell-penetrating peptides [WR]5 and [WR]4 as molecular transporters. To optimize further the utility of our developed peptides for targeted therapy in cancer cells using the redox condition, we designed a new genera
Externí odkaz:
https://doaj.org/article/2216796db19b4799b949af17d8146ec0
Autor:
Eman H. M. Mohammed, Sandeep Lohan, Tarra Ghaffari, Shilpi Gupta, Rakesh K. Tiwari, Keykavous Parang
Publikováno v:
Journal of medicinal chemistry. 65(23)
We designed a library of 24 cyclic peptides containing arginine (R) and tryptophan (W) residues in a sequential manner [R
Autor:
Dindyal Mandal, Eman H. M. Mohammed, Sandeep Lohan, Parvin Mandipoor, Darius Baradaran, Rakesh K. Tiwari, Keykavous Parang, Hamidreza Montazeri Aliabadi
Publikováno v:
Molecular pharmaceutics. 19(5)
RNA interference (RNAi) is a powerful tool capable of targeting virtually any protein without time-consuming and expensive drug development studies. However, due to obstacles facing efficient and safe delivery, RNAi-based therapeutic approach remains
Publikováno v:
European journal of medicinal chemistry. 235
Linear and cyclic amphiphilic peptides, (W
Autor:
Maha AlKhazindar, Shaima Ahmed El-Mowafi, Joanna Bojarska, Eman H M Mohammed, Ahmed O. Shalash, Istvan Toth, Zyta M. Ziora, Sherif M. Elnagdy, Mariusz Skwarczynski, Adam Mieczkowski, Keykavous Parang, Wojciech M. Wolf
Publikováno v:
Biomolecules, Vol 11, Iss 1515, p 1515 (2021)
Biomolecules
Biomolecules
Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of peptides widespread in nature, are unsurpassed in their structural and bio-functional diversity. DKPs, especially those containing proline, due to their unique feat
Autor:
Adam Viegas, Khalid Zoghebi, Simin Rahighi, Keykavous Parang, Razan Orfali, Meng Cui, Young-Woo Nam, Misa Nguyen, Miao Zhang, Eman H M Mohammed
Publikováno v:
Acta Physiologica. 231
Aim Small-conductance Ca2+ -activated potassium (SK) channels are activated exclusively by increases in intracellular Ca2+ that binds to calmodulin constitutively associated with the channel. Wild-type SK2 channels are activated by Ca2+ with an EC50
Autor:
Dindyal Mandal, Rakesh Tiwari, Magdy A. H. Zahran, Keykavous Parang, Eman H M Mohammed, Amany Mostafa Osman, Saghar Mozaffari
Publikováno v:
Molecules, Vol 25, Iss 2581, p 2581 (2020)
Molecules
Volume 25
Issue 11
Molecules
Volume 25
Issue 11
We have previously reported cyclic cell-penetrating peptides [WR]5 and [WR]4 as molecular transporters. To optimize further the utility of our developed peptides for targeted therapy in cancer cells using the redox condition, we designed a new genera