Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Eman, Namati"'
Autor:
Eman Namati
Publikováno v:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVII.
Autor:
Ryan J. Adam, Geoffrey McLennan, Anthony J. Fischer, Michael J. Welsh, Omar A. Itani, Mark J. Hoegger, Alexander J. Tucker, David A. Stoltz, Eman Namati, Maged Awadalla, Eric A. Hoffman
Publikováno v:
Proceedings of the National Academy of Sciences. 111:2355-2360
Mucociliary transport (MCT) is an innate defense mechanism that removes particulates, noxious material, and microorganisms from the lung. Several airway diseases exhibit abnormal MCT, including asthma, chronic bronchitis, and cystic fibrosis. However
Autor:
Farouc A. Jaffer, Roman Shubochkin, Jason R. McCarthy, Jin Won Kim, Brett E. Bouma, Hongki Yoo, Eman Namati, Theodore F. Morse, Guillermo J. Tearney, Vasilis Ntziachristos, Milen Shishkov
Publikováno v:
Nature medicine
Advancing our understanding of human coronary artery disease requires new methods that can be used in patients for studying atherosclerotic plaque microstructure in relation to the molecular mechanisms that underlie its initiation, progression, and c
Lung structure phenotype variation in inbred mouse strains revealed through in vivo micro-CT imaging
Autor:
Jessica C. Sieren, Eric A. Hoffman, Joseph M. Reinhardt, Amanda R. Smith, Eman Namati, Geoffrey McLennan, Jacqueline Thiesse
Publikováno v:
Journal of Applied Physiology. 109:1960-1968
Within pulmonary research, the development of mouse models has provided insight into disease development, progression, and treatment. Structural phenotypes of the lung in healthy inbred mouse strains are necessary for comparison to disease models. To
Autor:
Amanda R. Smith, Melissa J. Suter, Shyam Ramachandran, Eman Namati, David A. Stoltz, Guillermo J. Tearney, Alejandro A. Pezzulo, Geoffrey McLennan, Paul B. McCray, Simon C. Kao, Michael V. Rector, Michael J. Welsh, David K. Meyerholz, Joseph Zabner
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 182:1251-1261
Although airway abnormalities are common in patients with cystic fibrosis (CF), it is unknown whether they are all secondary to postnatal infection and inflammation, which characterize the disease.To learn whether loss of the cystic fibrosis transmem
Autor:
Jessica C. Sieren, Eric A. Hoffman, Geoffrey McLennan, Eman Namati, Jacqueline Thiesse, Alan F. Ross
Publikováno v:
Medical Physics. 37:4793-4805
Purpose: Small animal micro-CT imaging is being used increasingly in preclinical biomedical research to provide phenotypic descriptions of genomic models. Most of this imaging is coincident with animal death and is used to show the extent of disease
An Automated Segmentation Approach for Highlighting the Histological Complexity of Human Lung Cancer
Autor:
B. De Young, Geoffrey McLennan, A. Bell, Jacqueline Thiesse, Jessica C. Sieren, A. R. Smith, Jamie A. Weydert, Eman Namati
Publikováno v:
Annals of Biomedical Engineering. 38:3581-3591
Lung cancer nodules, particularly adenocarcinoma, contain a complex intermixing of cellular tissue types: incorporating cancer cells, fibroblastic stromal tissue, and inactive fibrosis. Quantitative proportions and distributions of the various tissue
Autor:
Jacqueline Thiesse, Joseph M. Reinhardt, Geoffrey McLennan, Jessica C. Sieren, Eric A. Hoffman, Jered Sieren, Jamie A. Weydert, Eman Namati
Publikováno v:
Academic Radiology. 17:169-180
Rationale and Objectives Multimodal imaging techniques for capturing normal and diseased human anatomy and physiology are being developed to benefit patient clinical care, research, and education. In the past, the incorporation of histopathology into
Publikováno v:
Clinical Pharmacology & Therapeutics. 84:517-522
The survival rate for lung cancer patients has barely improved over the past 30 years. New evaluation benchmarks for cancer response are needed to test therapy agents in a cost-effective and timely manner. From recent work, it is evident that primary
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Pulmonary emphysema is usually the result of chronic exposure to cigarette smoke in at risk individuals. To investigate the hypothesis that lung damage in emphysema results from coincident weakening in the structural properties of the tissue and incr