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pro vyhledávání: '"Emad Seyed Sadr"'
Autor:
Deborah Maret, Mohamad Seyed Sadr, Emad Seyed Sadr, David R Colman, Rolando F Del Maestro, Nabil G Seidah
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 10, Pp 880-892 (2012)
We recently demonstrated that lack of Furin-processing of the N-cadherin precursor (proNCAD) in highly invasive melanoma and brain tumor cells results in the cell-surface expression of a nonadhesive protein favoring cell migration and invasion in vit
Externí odkaz:
https://doaj.org/article/134a3339e6dc451da3660c6b7cdbafa9
Autor:
Katharina Seystahl, Davide Mangani, Michael Weller, Hans Binder, Edith Willscher, Emad Seyed Sadr, Ghazaleh Tabatabai, Guido Reifenberger, Hannah Schneider
Publikováno v:
Neuro-oncology. 18(12)
BackgroundThe vascular endothelial growth factor (VEGF) and transforming growth factor (TGF)–β pathways regulate key biological features of glioblastoma. Here we explore whether the TGF-β pathway, which promotes angiogenesis, invasiveness, and im
Autor:
Ghazaleh Tabatabai, Davide Mangani, Hans Binder, Guido Reifenberger, Hannah Schneider, Katharina Seystahl, Michael Weller, Emad Seyed Sadr, Edith Willscher
Publikováno v:
Cancer Immunology Research. 5:B88-B88
The vascular endothelial growth factor (VEGF) and transforming growth factor (TGF)-β are key target molecules in glioblastoma that are interdependently regulated. Both pathways drive key malignant features in glioma cells such as angiogenesis, invas
Autor:
Peter S. McPherson, Mathilde Chaineau, Sarah Konefal, Mohamed Seyed Sadr, Deborah Maret, Rolando F. Del Maestro, Emad Seyed Sadr, Patrick D. Allaire, Maryam Fotouhi, Brigitte Ritter
Publikováno v:
Journal of cell science. 126(Pt 3)
Cells inversely adjust the plasma membrane levels of integrins and cadherins during cell migration and cell-cell adhesion but the regulatory mechanisms that coordinate these trafficking events remain unknown. Here, we demonstrate that the small GTPas
Autor:
Mohamad Seyed Sadr, Deborah Maret, Nabil G. Seidah, Rolando F. Del Maestro, Emad Seyed Sadr, David R. Colman
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 10, Pp 880-892 (2012)
We recently demonstrated that lack of Furin-processing of the N-cadherin precursor (proNCAD) in highly invasive melanoma and brain tumor cells results in the cell-surface expression of a nonadhesive protein favoring cell migration and invasion in vit
Autor:
Rolando F. Del Maestro, Alain Tessier, Carmen Sabau, Mohamad Seyed Sadr, J. Alshami, Dragosh Catana, Emad Seyed Sadr
Publikováno v:
Molecular Cancer Therapeutics. 10:B24-B24
The current standard of care for glioblastoma includes surgery, radiotherapy and chemotherapeutic agents such as temozolomide (TMZ), a DNA methylating compound. The cytotoxic effects of TMZ have been linked to guanine methylation at the N7 and O6 pos