Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Emad I Arafa"'
Autor:
Neelou S. Etesami, Kimberly A. Barker, Anukul T. Shenoy, Carolina Lyon De Ana, Emad I. Arafa, Gabrielle N. Grifno, Adeline M. Matschulat, Michael E. Vannini, Riley M. F. Pihl, Michael P. Breen, Alicia M. Soucy, Wesley N. Goltry, Catherine T. Ha, Hanae Betsuyaku, Jeffrey L. Browning, Xaralabos Varelas, Katrina E. Traber, Matthew R. Jones, Lee J. Quinton, Paul J. Maglione, Hadi T. Nia, Anna C. Belkina, Joseph P. Mizgerd
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recovery from respiratory pneumococcal infections generates lung-localized protection against heterotypic bacteria, mediated by resident memory lymphocytes. Optimal protection in mice requires re-exposure to pneumococcus within days of initial infect
Externí odkaz:
https://doaj.org/article/49ecad14795045e78212ea23aeaa9d05
Autor:
Filiz T. Korkmaz, Anukul T. Shenoy, Elise M. Symer, Lillia A. Baird, Christine V. Odom, Emad I. Arafa, Ernest L. Dimbo, Elim Na, William Molina-Arocho, Matthew Brudner, Theodore J. Standiford, Jawahar L. Mehta, Tatsuya Sawamura, Matthew R. Jones, Joseph P. Mizgerd, Katrina E. Traber, Lee J. Quinton
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Identifying host factors that contribute to pneumonia incidence and severity are of utmost importance to guiding the development of more effective therapies. Lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1, encoded by OLR1) is a scaven
Externí odkaz:
https://doaj.org/article/b320f241dc9942bba46957a1d10f8c08
Autor:
Anukul T. Shenoy, Carolina Lyon De Ana, Emad I. Arafa, Isabelle Salwig, Kimberly A. Barker, Filiz T. Korkmaz, Aditya Ramanujan, Neelou S. Etesami, Alicia M. Soucy, Ian M. C. Martin, Brian R. Tilton, Anne Hinds, Wesley N. Goltry, Hasmeena Kathuria, Thomas Braun, Matthew R. Jones, Lee J. Quinton, Anna C. Belkina, Joseph P. Mizgerd
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The maintenance of T resident memory (TRM) cells within pulmonary tissues is incompletely understood. Here the authors show that antigen presentation by lung epithelial cells maintains function and phenotype of pulmonary TRM cells within specific loc
Externí odkaz:
https://doaj.org/article/c4c893d49d55411c8e49e957418469ec
Autor:
Emad I. Arafa, Anukul T. Shenoy, Kimberly A. Barker, Neelou S. Etesami, Ian M.C. Martin, Carolina Lyon De Ana, Elim Na, Christine V. Odom, Wesley N. Goltry, Filiz T. Korkmaz, Alicia K. Wooten, Anna C. Belkina, Antoine Guillon, E. Camilla Forsberg, Matthew R. Jones, Lee J. Quinton, Joseph P. Mizgerd
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Recovery from pneumococcal pneumonia remodels the pool of alveolar macrophages so that they exhibit new surface marker profiles, transcriptomes, metabolomes, and responses to infection. Mechanisms mediating alveolar macrophage phenotypes after pneumo
Externí odkaz:
https://doaj.org/article/010788fe07a74054bdcc06f35fc12205
Autor:
Alicia K. Wooten, Anukul T. Shenoy, Emad I. Arafa, Hisashi Akiyama, Ian M. C. Martin, Matthew R. Jones, Lee J. Quinton, Suryaram Gummuluru, Guangchun Bai, Joseph P. Mizgerd
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cyclic di-AMP (c-di-AMP) is an important signaling molecule for pneumococci, and as a uniquely prokaryotic product it can be recognized by mammalian cells as a danger signal that triggers innate immunity. Roles of c-di-AMP in directing host responses
Externí odkaz:
https://doaj.org/article/a10ba0063d5443d69311bc25de555b0e
Autor:
Alicia K, Wooten, Anukul T, Shenoy, Emad I, Arafa, Hisashi, Akiyama, Ian M C, Martin, Matthew R, Jones, Lee J, Quinton, Suryaram, Gummuluru, Guangchun, Bai, Joseph P, Mizgerd
Publikováno v:
Frontiers in Immunology
Cyclic di-AMP (c-di-AMP) is an important signaling molecule for pneumococci, and as a uniquely prokaryotic product it can be recognized by mammalian cells as a danger signal that triggers innate immunity. Roles of c-di-AMP in directing host responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::828300ad6c503c085415badb38ec93f5
https://pubmed.ncbi.nlm.nih.gov/32300347
https://pubmed.ncbi.nlm.nih.gov/32300347
Autor:
Anukul T, Shenoy, Gregory A, Wasserman, Emad I, Arafa, Alicia K, Wooten, Nicole M S, Smith, Ian M C, Martin, Matthew R, Jones, Lee J, Quinton, Joseph P, Mizgerd
Publikováno v:
Mucosal immunology
Previous pneumococcal experience establishes lung-resident IL-17A-producing CD4+ memory TRM cells that accelerate neutrophil recruitment against heterotypic pneumococci. Herein, we unravel a novel crosstalk between CD4+ TRM cells and lung epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a60fff0b5cfc55b05cfee1494e6e9234
https://pubmed.ncbi.nlm.nih.gov/31748706
https://pubmed.ncbi.nlm.nih.gov/31748706
Autor:
Anukul T. Shenoy, Emad I Arafa, Carolina Lyon De Ana, Kimberly A Barker, Filiz T Korkmaz, Aditya Ramanujan, Neelou S Etesami, Ian MC Martin, Brian R Tilton, Anne Hinds, Wesley N Goltry, Hasmeena Kathuria, Matthew R Jones, Lee J Quinton, Anna C Belkina, Joseph P Mizgerd
Publikováno v:
The Journal of Immunology. 206:93.07-93.07
Barrier tissues are sentinelled by CD4+ TRM cells with potent anti-microbial activities and considerable lineage plasticity. We hypothesized that local antigen presentation by lung epithelial cells (LECs) instruct CD4+ TRM cell activities. Pneumococc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ec1bc5a4eba65032bc3fbcdf575a22
https://doi.org/10.4049/jimmunol.206.supp.93.07
https://doi.org/10.4049/jimmunol.206.supp.93.07