Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Emad Bahrami"'
Autor:
Jennifer Faber, David Kügler, Emad Bahrami, Lea-Sophie Heinz, Dagmar Timmann, Thomas M. Ernst, Katerina Deike-Hofmann, Thomas Klockgether, Bart van de Warrenburg, Judith van Gaalen, Kathrin Reetz, Sandro Romanzetti, Gulin Oz, James M. Joers, Jorn Diedrichsen, Martin Reuter, Paola Giunti, Hector Garcia-Moreno, Heike Jacobi, Johann Jende, Jeroen de Vries, Michal Povazan, Peter B. Barker, Katherina Marie Steiner, Janna Krahe
Publikováno v:
NeuroImage, Vol 264, Iss , Pp 119703- (2022)
Quantifying the volume of the cerebellum and its lobes is of profound interest in various neurodegenerative and acquired diseases. Especially for the most common spinocerebellar ataxias (SCA), for which the first antisense oligonculeotide-base gene s
Externí odkaz:
https://doaj.org/article/fda98a646f86424daa91258742f29642
Autor:
Lori L O'Brien, Qiuyu Guo, Emad Bahrami-Samani, Joo-Seop Park, Sean M Hasso, Young-Jin Lee, Alan Fang, Albert D Kim, Jinjin Guo, Trudy M Hong, Kevin A Peterson, Scott Lozanoff, Ramya Raviram, Bing Ren, Ben Fogelgren, Andrew D Smith, Anton Valouev, Andrew P McMahon
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007181 (2018)
Nephron progenitor number determines nephron endowment; a reduced nephron count is linked to the onset of kidney disease. Several transcriptional regulators including Six2, Wt1, Osr1, Sall1, Eya1, Pax2, and Hox11 paralogues are required for specifica
Externí odkaz:
https://doaj.org/article/435e97a2f642461e8fa6f0e4415c1cce
Autor:
Zhijie Xie, Shayna Stein, Levon Demirdjian, Eddie Park, Ying Nian Wu, Emad Bahrami-Samani, Yang Pan, Yungang Xu, Yi Xing
Publikováno v:
American Journal of Human Genetics
Summary RNA sequencing (RNA-seq) is a powerful technology for studying human transcriptome variation. We introduce PAIRADISE (Paired Replicate Analysis of Allelic Differential Splicing Events), a method for detecting allele-specific alternative splic
Autor:
Jenna M. Hendershot, Mohammad Abbasi, Laura Fortier, Maleah Benn, Camille Giacobone, Richard Del Mastro, Emad Bahrami-Samani, Amin R. Mazloom, Pankaj Oberoi
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 214
Preeclampsia is a serious condition responsible for much pregnancy-related morbidity and mortality. Diagnosis of preeclampsia is difficult due to the non-specific and subjective nature of symptoms of the disease. To reduce the subjective decision mak
Autor:
Emad Bahrami-Samani, Yi Xing
Publikováno v:
American Journal of Human Genetics
Gene expression is tightly regulated at the post-transcriptional level through splicing, transport, translation, and decay. RNA-binding proteins (RBPs) play key roles in post-transcriptional gene regulation, and genetic variants that alter RBP-RNA in
Autor:
Mehdi Noroozi, Juergen Gall, Mohsen Fayyaz, Ehsan Adeli, Luc Van Gool, Ali Diba, Emad Bahrami
Publikováno v:
CVPR
While state-of-the-art 3D Convolutional Neural Networks (CNN) achieve very good results on action recognition datasets, they are computationally very expensive and require many GFLOPs. While the GFLOPs of a 3D CNN can be decreased by reducing the tem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94731cf9b54ec2221cb6c4dc80f760a2
http://arxiv.org/abs/2011.08652
http://arxiv.org/abs/2011.08652
Autor:
Douglas L. Black, Chia-Ho Lin, Yi Ying, James A. Wohlschlegel, Andrey Damianov, Diana Tran, Kelsey C. Martin, Ji-Ann Lee, Emad Bahrami-Samani, Yi Xing, Ajay A. Vashisht
Publikováno v:
Cell, vol 165, iss 3
Rbfox proteins control alternative splicing and posttranscriptional regulation in mammalian brain and are implicated in neurological disease. These proteins recognize the RNA sequence (U)GCAUG, but their structures and diverse roles imply a variety o
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 43, iss 22
Nucleic acids research, vol 43, iss 22
RNA-seq has become a popular technology for studying genetic variation of pre-mRNA alternative splicing. Commonly used RNA-seq aligners rely on the consensus splice site dinucleotide motifs to map reads across splice junctions. Consequently, genomic
Autor:
Andrew D. Smith, Mei Qiao, Myriam Gorospe, Helder I. Nakaya, Kotb Abdelmohsen, Patrícia R. Araújo, Jernej Ule, Raquel de Sousa Abreu, Caspar D. Kühnöl, Emad Bahrami-Samani, Philip J. Uren, Jennifer L. Martindale, Bruna R. Correa, Rebecca Pötschke, Dat T. Vo, Luiz O. F. Penalva, Suzanne C. Burns
Publikováno v:
Molecular and Cellular Biology. 35:2965-2978
The conserved RNA-binding protein Musashi1 (MSI1) has emerged as a key oncogenic factor in numerous solid tumors, including glioblastoma. However, its mechanism of action has not yet been established comprehensively. To identify its target genes comp
Autor:
Patrícia R. Araújo, Dat T. Vo, Andrew D. Smith, Emad Bahrami-Samani, Christine Vogel, Philip J. Uren, Luiz O. F. Penalva
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 6:291-310
Co- and post-transcriptional regulation of gene expression is complex and multifaceted, spanning the complete RNA lifecycle from genesis to decay. High-throughput profiling of the constituent events and processes is achieved through a range of techno