Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Emőke Borbély"'
1
Akademický článek
Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury
Autor: Brigitta Dukay, Fruzsina R. Walter, Judit P. Vigh, Beáta Barabási, Petra Hajdu, Tamás Balassa, Ede Migh, András Kincses, Zsófia Hoyk, Titanilla Szögi, Emőke Borbély, Bálint Csoboz, Péter Horváth, Lívia Fülöp, Botond Penke, László Vígh, Mária A. Deli, Miklós Sántha, Melinda E. Tóth
Publikováno v: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-24 (2021)
Abstract Background Heat-shock protein B1 (HSPB1) is among the most well-known and versatile member of the evolutionarily conserved family of small heat-shock proteins. It has been implicated to serve a neuroprotective role against various neurologic
Externí odkaz: https://doaj.org/article/713216accbf34c728f67915b544ae77e
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2
Akademický článek
Examination of Longitudinal Alterations in Alzheimer’s Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model, and the Effects of P33, a Putative Neuroprotective Agent Thereon
Autor: Titanilla Szögi, Emőke Borbély, Ildikó Schuster, Zsolt Bozsó, Miklós Sántha, Melinda E. Tóth, Botond Penke, Lívia Fülöp
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 18, p 10364 (2022)
Neurogenesis plays a crucial role in cognitive processes. During aging and in Alzheimer’s disease (AD), altered neurogenesis and neuroinflammation are evident both in C57BL/6J, APPSwe/PS1dE9 (Tg) mice and humans. AD pathology may slow down upon dru
Externí odkaz: https://doaj.org/article/8dd6477330d840d7a60ff0e497ca446b
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3
Akademický článek
Impact of Two Neuronal Sigma-1 Receptor Modulators, PRE084 and DMT, on Neurogenesis and Neuroinflammation in an Aβ1–42-Injected, Wild-Type Mouse Model of AD
Autor: Emőke Borbély, Viktória Varga, Titanilla Szögi, Ildikó Schuster, Zsolt Bozsó, Botond Penke, Lívia Fülöp
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 5, p 2514 (2022)
Alzheimer’s disease (AD) is the most common form of dementia characterized by cognitive dysfunctions. Pharmacological interventions to slow the progression of AD are intensively studied. A potential direction targets neuronal sigma-1 receptors (S1R
Externí odkaz: https://doaj.org/article/a6a666b18e974458a3d3faf7c808adf0
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4
Akademický článek
Hippocampal Sclerosis in Pilocarpine Epilepsy: Survival of Peptide-Containing Neurons and Learning and Memory Disturbances in the Adult NMRI Strain Mouse
Autor: Adrienne Mátyás, Emőke Borbély, András Mihály
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 1, p 204 (2021)
The present experiments reveal the alterations of the hippocampal neuronal populations in chronic epilepsy. The mice were injected with a single dose of pilocarpine. They had status epilepticus and spontaneously recurrent motor seizures. Three months
Externí odkaz: https://doaj.org/article/251e359aa316430abb7d0c8954691c11
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5
Akademický článek
Effects of the Pentapeptide P33 on Memory and Synaptic Plasticity in APP/PS1 Transgenic Mice: A Novel Mechanism Presenting the Protein Fe65 as a Target
Autor: Titanilla Szögi, Ildikó Schuster, Emőke Borbély, Andrea Gyebrovszki, Zsolt Bozsó, János Gera, Róbert Rajkó, Miklós Sántha, Botond Penke, Lívia Fülöp
Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 12, p 3050 (2019)
Regulated intramembrane proteolysis (RIP) of the amyloid precursor protein (APP) leads to the formation of fragments, among which the intracellular domain of APP (AICD) was also identified to be a causative of early pathological events. AICD-countera
Externí odkaz: https://doaj.org/article/cfa48ebc3d724cd9be101640c956a9a2
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6
Hippocampal Sclerosis in Pilocarpine Epilepsy: Survival of Peptide-Containing Neurons and Learning and Memory Disturbances in the Adult NMRI Strain Mouse
Autor: Adrienne, Mátyás, Emőke, Borbély, András, Mihály
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 204, p 204 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 204
The present experiments reveal the alterations of the hippocampal neuronal populations in chronic epilepsy. The mice were injected with a single dose of pilocarpine. They had status epilepticus and spontaneously recurrent motor seizures. Three months
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af35d430ec9e641972e06d3a7dd0d37
https://www.mdpi.com/1422-0067/23/1/204
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7
Post-diaminobenzidine Treatments for Double Stainings: Extension of Sulfide-Silver-Gold Intensification for Light and Fluorescent Microscopy
Autor: Titanilla Szögi, Ibolya Török, Emőke Borbély, E. Dobó, György Seprényi, Erzsébet Pór
Publikováno v: J Histochem Cytochem
Double staining protocols using the most popular immunoperoxidase techniques may raise difficulties. The two ordinary detection systems may cross-talk, when the primary antibodies are derived from phylogenetically closely related animals. A color shi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb4cca99e61dc3c88fbebedd1b051f6
https://doi.org/10.1369/0022155420942213
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8
Impact of Two Neuronal Sigma-1 Receptor Modulators, PRE084 and DMT, on Neurogenesis and Neuroinflammation in an Aβ
Autor: Emőke, Borbély, Viktória, Varga, Titanilla, Szögi, Ildikó, Schuster, Zsolt, Bozsó, Botond, Penke, Lívia, Fülöp
Publikováno v: International journal of molecular sciences. 23(5)
Alzheimer's disease (AD) is the most common form of dementia characterized by cognitive dysfunctions. Pharmacological interventions to slow the progression of AD are intensively studied. A potential direction targets neuronal sigma-1 receptors (S1Rs)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::940b9e61c896e59e4bf4241d48c4fb67
https://pubmed.ncbi.nlm.nih.gov/35269657
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9
Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury
Autor: Beáta Barabási, Zsófia Hoyk, Petra Hajdu, Emőke Borbély, Fruzsina R. Walter, Lívia Fülöp, Brigitta Dukay, László Vígh, Bálint Csoboz, Mária A. Deli, Ede Migh, Tamas Balassa, Titanilla Szögi, Miklós Sántha, Melinda Tóth, Peter Horvath, András Kincses, Botond Penke, Judit P. Vigh
Publikováno v: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-24 (2021)
Journal of Neuroinflammation
Background Heat-shock protein B1 (HSPB1) is among the most well-known and versatile member of the evolutionarily conserved family of small heat-shock proteins. It has been implicated to serve a neuroprotective role against various neurological disord
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9e24caf0ab0b6fe5e1f8b544d043a1
https://doi.org/10.1186/s12974-020-02070-2
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