Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Em, Cramer"'
Autor:
Sunitha N. Wickramasinghe, Jean-Paul Dommergues, V. Zupan, Jacques Delaunay, M. Dommergues, F Mielot, Gil Tchernia, N. Parez, Em Cramer, H. Chambost, J. B. Fieschi
Publikováno v:
British Journal of Haematology. 110:420-423
We report a case of congenital dyserythropoietic anaemia, type I, with severe pre- and postnatal manifestations. Exchange transfusions were required for fetal anaemia (3.5 g/dl) at 28 and 30 weeks of gestation. Transfusions were administered at birth
Publikováno v:
Blood. 77:694-699
The subcellular localization of the platelet membrane receptors glycoproteins (GP) Ib and IIb/IIIa [corrected] has been studied within resting platelets by a combination of biochemical and cytochemical techniques. While both GPIb and GPIIb/IIIa are l
Autor:
Em, Cramer, Gf, Savidge, Vainchenker W, Mc, Berndt, Dominique Pidard, Jp, Caen, Jm, Massé, Breton-Gorius J
Publikováno v:
Europe PubMed Central
Using an immunogold staining technique and electron microscopy, we investigated the localization of the alpha-granule pool of glycoprotein (GP) IIb-IIIa in normal platelets and maturing megakaryocytes (MK), in pathologic platelets from a patient with
Autor:
Veronique Witko-Sarsat, Em, Cramer, Hieblot C, Guichard J, Nusbaum P, Lopez S, Lesavre P, Halbwachs-Mecarelli L
Publikováno v:
Europe PubMed Central
Proteinase 3 (PR3), which is also called myeloblastin, the target autoantigen for antineutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis, is a serine proteinase stored in azurophil granules of human neutrophils. We have previously s
Publikováno v:
Europe PubMed Central
Multimerin is a massive, soluble, homomultimeric, factor V-binding protein found in platelet alpha-granules and in vascular endothelium. Unlike platelets, endothelial cells contain multimerin within granules that lack the secretory granule membrane p
Autor:
Jean-Luc Villeval, Cohen-Solal K, Tulliez M, Giraudier S, Guichard J, Sa, Burstein, Em, Cramer, Vainchenker W, Wendling F
Publikováno v:
Europe PubMed Central
To evaluate the effects of long-term, high-dose exposure to thrombopoietin (TPO), lethally irradiated mice were grafted with bone marrow cells infected with a retrovirus carrying the murine TPO cDNA. Mice were studied for 10 months after transplantat
Publikováno v:
Europe PubMed Central
We recently described a Quebec family with an autosomal dominant bleeding disorder characterized by mildly reduced-low normal platelet counts, an epinephrine aggregation defect, multimerin deficiency, and proteolytic degradation of several, soluble a
Publikováno v:
Blood. 84(6)
CD9 (p24) and PECAM1 (CD31) antigens are well-defined components of the platelet plasma membrane. Both are integral glycoproteins (GPs) implicated in the adhesive and aggregative properties of human platelets. In the present report, we have investiga
Publikováno v:
Blood. 82(10)
CD36 (glycoprotein [GP] IV) is a membrane GP of 88 kD found on monocytes, endothelial cells, and platelets. It may serve as a receptor for collagen and is also able to bind thrombospondin (TSP), because a monoclonal antibody to CD36 inhibits TSP bind
Autor:
G. F. Savidge, A Lahiri, S Bhattacharya, Paul Harrison, Sj Machin, R Faint, Barry Wilbourn, Em Cramer, D. Tenza, I. J. Mackie
Publikováno v:
British journal of haematology. 82(4)
Recent evidence suggests that platelet alpha-granule fibrinogen (fg) is derived from the plasma pool. Since platelets from patients with Type I Glanzmann's thrombasthenia (GT) are deficient in intracellular fibrinogen (fg) it was hypothesized that Gp