The lipooligosaccharide of the gut symbiont Akkermansia muciniphila exhibits a remarkable structure and TLR signaling capacity.

Autor: Garcia-Vello P; Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy., Tytgat HLP; Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands.; Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., Lausanne, Switzerland., Elzinga J; Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands., Van Hul M; Louvain Drug Research Institute, Metabolism and Nutrition Research group, UCLouvain, Université Catholique de Louvain, Brussels, Belgium.; Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), WELBIO department, WEL Research Institute, avenue Pasteur, 6, Wavre, Belgium., Plovier H; Louvain Drug Research Institute, Metabolism and Nutrition Research group, UCLouvain, Université Catholique de Louvain, Brussels, Belgium.; Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), WELBIO department, WEL Research Institute, avenue Pasteur, 6, Wavre, Belgium., Tiemblo-Martin M; Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy., Cani PD; Louvain Drug Research Institute, Metabolism and Nutrition Research group, UCLouvain, Université Catholique de Louvain, Brussels, Belgium.; Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), WELBIO department, WEL Research Institute, avenue Pasteur, 6, Wavre, Belgium.; Institute of Experimental and Clinical Research (IREC), UCLouvain, Université catholique de Louvain, Brussels, Belgium., Nicolardi S; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Fragai M; Magnetic Resonance Center (CERM), CIRMMP and Department of Chemistry 'Ugo Schiff', University of Florence, Florence, Italy., De Castro C; Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy., Di Lorenzo F; Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy., Silipo A; Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy.; Department of Chemistry, School of Science, Osaka University, Osaka, Japan., Molinaro A; Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy. molinaro@unina.it.; Department of Chemistry, School of Science, Osaka University, Osaka, Japan. molinaro@unina.it., de Vos WM; Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands. willem.devos@wur.nl.; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland. willem.devos@wur.nl.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 27; Vol. 15 (1), pp. 8411. Date of Electronic Publication: 2024 Sep 27.

Revealing Glycosylation Patterns in In Vitro -Produced Mucus Exposed to Pasteurized Mucus-Associated Intestinal Microbes by MALDI-TOF-MS and PGC-LC-MS/MS.

Autor: de Ram C; Laboratory of Food Chemistry, Wageningen University & Research, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands., van der Lugt B; Human Nutrition and Health, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands., Elzinga J; Laboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands., Geerlings S; Laboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands., Steegenga WT; Human Nutrition and Health, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands., Belzer C; Laboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands., Schols HA; Laboratory of Food Chemistry, Wageningen University & Research, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.

Publikováno v: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Jul 10; Vol. 72 (27), pp. 15345-15356. Date of Electronic Publication: 2024 Jun 26.

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Comparative Genomics and Physiology of Akkermansia muciniphila Isolates from Human Intestine Reveal Specialized Mucosal Adaptation.

Autor: Ouwerkerk JP; Laboratory of Microbiology, Wageningen University, 6708 WE Wageningen, The Netherlands., Tytgat HLP; Laboratory of Microbiology, Wageningen University, 6708 WE Wageningen, The Netherlands., Elzinga J; Laboratory of Microbiology, Wageningen University, 6708 WE Wageningen, The Netherlands., Koehorst J; Laboratory of Systems and Synthetic Biology, Wageningen University, 6708 WE Wageningen, The Netherlands., Van den Abbeele P; Center for Microbial Ecology and Technology (CMET), Ghent University, 9000 Ghent, Belgium., Henrissat B; Department of Biotechnology and Biomedicine (DTU Bioengineering), Technical University of Denmark, 2800 Lyngby, Denmark.; Department of Biological Sciences, King Abdulaziz University, Jeddah 22254, Saudi Arabia., Gueimonde M; Instituto de Productos Lácteos de Asturios (IPLA), Consejo Superior de Investigaciones Científicas (CSIC), 28006 Madrid, Spain., Cani PD; Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), UCLouvain, Université Catholique de Louvain, 1348 Brussels, Belgium., Van de Wiele T; Center for Microbial Ecology and Technology (CMET), Ghent University, 9000 Ghent, Belgium., Belzer C; Laboratory of Microbiology, Wageningen University, 6708 WE Wageningen, The Netherlands., de Vos WM; Laboratory of Microbiology, Wageningen University, 6708 WE Wageningen, The Netherlands.; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00100 Helsinki, Finland.

Publikováno v: Microorganisms [Microorganisms] 2022 Aug 09; Vol. 10 (8). Date of Electronic Publication: 2022 Aug 09.