Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elzbieta Luchowska"'
Autor:
Piotr Luchowski, Joanna Wojczal, Maciej Szmygin, Elzbieta Luchowska, Katarzyna Prus, Michał Sojka, Konrad Rejdak
Publikováno v:
Neurologia i Neurochirurgia Polska. 55:494-498
Introduction: We aimed to compare 3-month clinical outcomes after mechanical thrombectomy (MT) in patients transferred directly to a comprehensive stroke centre (‘mothership’, MS) to the outcomes of patients transferred secondarily from primary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6148c09730a48e32778dd1f47ada3a4c
https://doi.org/10.5603/pjnns.a2021.0050
https://doi.org/10.5603/pjnns.a2021.0050
Autor:
Maciej Szmygin, Joanna Wojczal, Elzbieta Luchowska, Piotr Luchowski, Michał Sojka, Konrad Rejdak, Katarzyna Prus
Publikováno v:
Clinical neurology and neurosurgery. 206
Background This study evaluated 3-months clinical outcome after mechanical thrombectomy (MT) in stroke patients transferred to a comprehensive stroke center (CSC) from a rural and urban areas in a Lubelskie province, the third largest province in Pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b1de6fcd45b5490e8c0a0c6cc7730e
https://pubmed.ncbi.nlm.nih.gov/34015697
https://pubmed.ncbi.nlm.nih.gov/34015697
Publikováno v:
Neuroscience Letters. 435:169-173
We describe a novel aspect of action of memantine ex vivo, in the brain cortical slices and in vitro, in mixed glial cultures. The drug potently increased the production of kynurenic acid, an endogenous tryptophan metabolite blocking N-methyl-D-aspar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f77931b24494a0eac63bdc674a09b69
https://doi.org/10.1016/j.neulet.2008.02.027
https://doi.org/10.1016/j.neulet.2008.02.027
Autor:
Jerzy W. Lazarewicz, R. Paczek, Apolonia Ziembowicz, Tomasz Kocki, Ewa M. Urbańska, Elzbieta Luchowska, Piotr Luchowski, Waldemar A. Turski, Marian Wielosz
Publikováno v:
Journal of Neuroscience Research. 79:375-382
Increased serum level of homocysteine, a sulfur-containing amino acid, is considered a risk factor in vascular disorders and in dementias. The effect of homocysteine and metabolically related compounds on brain production of kynurenic acid (KYNA), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46da45e59e9943380f83970ecaf11a93
https://doi.org/10.1002/jnr.20359
https://doi.org/10.1002/jnr.20359
Publikováno v:
Neuroscience Letters. 330:49-52
The aim of the present study was to evaluate the effect of mitochondrial inhibitors, 1-methyl-4-phenylpyridinium (MPP(+)) and 3-nitropropionic acid (3-NPA), on the brain production of endogenous glutamate antagonist, kynurenic acid (KYNA). MPP(+) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc94d32c6833ec9c449529fda13dc74
https://doi.org/10.1016/s0304-3940(02)00735-8
https://doi.org/10.1016/s0304-3940(02)00735-8
Publikováno v:
European Journal of Pharmacology. 431:209-214
In this study, we evaluated whether beta-adrenoceptor antagonists may modify the protective efficacy of dizocilpine (MK-801), a NMDA receptor antagonist, and 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine (GYKI 52466), a non-NMDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba6f7f704babaf028ba746d16ceb4dc
https://doi.org/10.1016/s0014-2999(01)01452-2
https://doi.org/10.1016/s0014-2999(01)01452-2
Autor:
Renata Kloc, Ewa M. Urbańska, Marian Wielosz, Sebastian Wnuk, Elzbieta Luchowska, Bartosz Olajossy, Björn Owe-Larsson
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 33(3)
The central levels of endogenous tryptophan metabolite kynurenic acid (KYNA), an antagonist of N-methyl-d-aspartate (NMDA) and alpha7-nicotinic receptors, affect glutamatergic and dopaminergic neurotransmission. Here, we demonstrate that selective ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a493318db0297c66a43aabc50567a92
https://pubmed.ncbi.nlm.nih.gov/19439240
https://pubmed.ncbi.nlm.nih.gov/19439240
Autor:
Elzbieta, Luchowska, Renata, Kloc, Sebastian, Wnuk, Bartosz, Olajossy, Marian, Wielosz, Ewa M, Urbańska
Publikováno v:
Pharmacological reports : PR. 60(4)
The effect of a beta(2)-adrenergic agonist, clenbuterol on the production of a glutamate receptor antagonist, kynurenic acid was studied in vitro. Clenbuterol enhanced the production of kynurenic acid in brain cortical slices (0.1-1.0 mM) and in glia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cd7f8186f13a076fec51658155dc00f
https://pubmed.ncbi.nlm.nih.gov/18799828
https://pubmed.ncbi.nlm.nih.gov/18799828
Autor:
Ewa M, Urbańska, Piotr, Luchowski, Elzbieta, Luchowska, Jarosław, Pniewski, Radosław, Woźniak, Małgorzata, Chodakowska-Zebrowska, Jerzy, Lazarewicz
Publikováno v:
Pharmacological reports : PR. 58(4)
KYNA, an antagonist of ionotropic glutamate receptors and alpha7 nicotinic receptors, has been found as well in the brain as in the periphery. The altered metabolism of KYNA, especially its deficiency, can lead to the enhanced glutamate-mediated exci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7062c288db9a47b8f6c3ba2057cd6856
https://pubmed.ncbi.nlm.nih.gov/16963796
https://pubmed.ncbi.nlm.nih.gov/16963796
Publikováno v:
Acta neurobiologiae experimentalis. 63(2)
Kynurenic acid (KYNA), the only known endogenous glutamate antagonist, is produced in the brain by kynurenine aminotransferases (KATs) I and II. Mitochondrial toxins, 1-methyl-4-phenylpyridinium (MPP +) and 3-nitropropionic acid (3-NPA), were previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6bed0c27c0d655d122ca6b5ada65f047
https://pubmed.ncbi.nlm.nih.gov/12926536
https://pubmed.ncbi.nlm.nih.gov/12926536