Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Elzbieta Glaser"'
Autor:
Dario Brunetti, Janniche Torsvik, Cristina Dallabona, Pedro Teixeira, Pawel Sztromwasser, Erika Fernandez‐Vizarra, Raffaele Cerutti, Aurelio Reyes, Carmela Preziuso, Giulia D'Amati, Enrico Baruffini, Paola Goffrini, Carlo Viscomi, Ileana Ferrero, Helge Boman, Wenche Telstad, Stefan Johansson, Elzbieta Glaser, Per M Knappskog, Massimo Zeviani, Laurence A Bindoff
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 3, Pp 176-190 (2015)
Abstract Mitochondrial dysfunction and altered proteostasis are central features of neurodegenerative diseases. The pitrilysin metallopeptidase 1 (PITRM1) is a mitochondrial matrix enzyme, which digests oligopeptides, including the mitochondrial targ
Externí odkaz:
https://doaj.org/article/9e38dde157b64f9cb256e35e44049577
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 405-412 (2015)
Organellar proteins synthesized in the cytosol are usually selective for only one destination in a cell but some proteins are localized in more than one compartment, for example in both mitochondria and chloroplasts. The mechanism of dual targeting o
Externí odkaz:
https://doaj.org/article/da503684a78b4714bd61b9af6cc153e8
Publikováno v:
Journal of experimental botany. 73(1)
Plant endosymbiotic organelles such as mitochondria and chloroplasts harbour a wide array of biochemical reactions. As a part of protein homeostasis to maintain organellar activity and stability, unwanted proteins and peptides need to be completely d
Autor:
Pedro Teixeira, Beata Kmiec, Abi S Ghifari, Elzbieta Glaser, Adriana Pružinská, Monika W. Murcha
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES. 104(5)
Most mitochondrial proteins are synthesised in the cytosol and targeted into the organelle via N-terminal targeting peptides that are cleaved upon import. The free targeting peptide is subsequently processed in a stepwise manner, with single amino ac
Autor:
Rui M. M. Branca, Elzbieta Glaser, Beata Kmiec, Pedro Teixeira, Janne Lehtiö, Monika W. Murcha
Publikováno v:
Molecular Plant. 11:342-345
A Common Peptidolytic Mechanism for Targeting Peptide Degradation in Mitochondria and Chloroplasts
Autor:
Ronnie P.-A. Berntsson, Cecilia Wallin, Beata Kmiec, Pål Stenmark, Maria Ankarcrona, Geoffrey Masuyer, Sebastian K.T.S. Wärmländer, Pedro Teixeira, Astrid Gräslund, Janne Lehtiö, Rui M. M. Branca, Catarina Moreira Pinho, Elzbieta Glaser
Publikováno v:
Journal of Molecular Biology. 430:348-362
Proteolysis plays an important role in mitochondrial biogenesis, from the processing of newly imported precursor proteins to the degradation of mitochondrial targeting peptides. Disruption of peptide degradation activity in yeast, plant and mammalian
Autor:
Tom Walsh, Paul Renbaum, Bassam Abu Libdeh, Pedro-Filipe Teixeira, Dario Brunetti, Reeval Segel, Rachel Beeri, Yeshaya Langer, Fouad Zahdeh, Ephrat Levy-Lahad, Suleyman Gulsuner, Enrico Baruffini, Ariella Weinberg-Shukron, Massimo Zeviani, Maher Shahrour, Roberta Ruotolo, Imad Dweikat, Elzbieta Glaser, Mary Claire King, Sharon Zeligson, Adi Aran
ObjectiveTo identify the genetic basis of a childhood-onset syndrome of variable severity characterised by progressive spinocerebellar ataxia, mental retardation, psychotic episodes and cerebellar atrophy.MethodsIdentification of the underlying mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abc59b9bb406afd3040708c895309a3
Autor:
Ute Roessner, Yan Wang, Chris Carrie, Shaobai Huang, James Whelan, Beata Kmiec, Owen Duncan, Monika W. Murcha, Pedro Teixeira, Oliver Berkowitz, Elzbieta Glaser, Simon R. Law, Wenhui Lyu, A. Harvey Millar, Jordan D. Radomiljac, Reena Narsai, Olivier Van Aken
Publikováno v:
Molecular Plant. 9:696-710
At12Cys-1 (At5g64400) and At12Cys-2 (At5g09570) are two closely related isogenes that encode small, twin cysteine proteins, typically located in mitochondria. At12Cys-2 transcript is induced in a variety of mutants with disrupted mitochondrial protei
Autor:
Beata Kmiec, Lu Li, Rui M. M. Branca, Elzbieta Glaser, Yan Wang, James Whelan, Oliver Berkowitz, Janne Lehtiö, Pedro Teixeira, Monika W. Murcha
Publikováno v:
The Plant journal : for cell and molecular biology. 96(4)
The stepwise degradation of peptides to amino acids in plant mitochondria and chloroplasts is catalyzed by a network of oligopeptidases (presequence protease PreP, organellar oligopeptidase OOP) and aminopeptidases. In the present report, we show tha
Autor:
Elzbieta Glaser, James Whelan
Publikováno v:
Annual Plant Reviews Volume 31: Plant Mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f8310d8bcc1e6025f66d78d33045a6
https://doi.org/10.1002/9781119312994.apr0325
https://doi.org/10.1002/9781119312994.apr0325