Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elzbieta Fiedor"'
Autor:
Agnieszka Rak, Anna Hejmej, Monika Słupecka-Ziemilska, Jaroslaw Woliński, Elzbieta Fiedor, Barbara Bilinska, Ewa Gregoraszczuk
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 49(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498593847d453ffdad76a1780ea618a5
https://pubmed.ncbi.nlm.nih.gov/28759941
https://pubmed.ncbi.nlm.nih.gov/28759941
Autor:
Federico Malusa, Eliza Majewska, Marion Chapellier, Aniela Golas, Jerzy Ostrowski, Magdalena Cybulska, Tomasz Rzymski, Michal Combik, Magdalena Masiejczyk, Marcus Järås, Michal Mikula, Katarzyna Wiklik, Krzysztof Brzózka, Przemyslaw Juszczynski, Milena Mazan, Maciej Mikulski, Elzbieta Fiedor, Pawel Chrom
Publikováno v:
Blood. 134:3774-3774
Introduction Targeting Cyclin Dependent Kinase 8 (CDK8) is a novel therapeutic strategy for Acute Myeloid Leukemia (AML), a disease associated with poor outcome. CDK8 has been implicated in the regulation of transcription, however antileukemic mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e59433f44f8fac47583fbbf62ec5643
https://doi.org/10.1182/blood-2019-128073
https://doi.org/10.1182/blood-2019-128073
Autor:
Michal Mikula, Arkadiusz Białas, Anna Polak, Aniela Golas, Krzysztof Brzózka, Urszula Kuklinska, Jerzy Ostrowski, Magdalena Cybulska, Przemyslaw Juszczynski, Michal Kopczynski, Michalina Dabrowska, Tomasz Rzymski, Zuzanna Sandowska-Markiewicz, Milena Mazan, Renata Windak, Eliza Majewska, Malgorzata Statkiewicz, Michal Combik, Magdalena Masiejczyk, Maciej Mikulski, Katarzyna Wiklik, Elzbieta Fiedor, Aleksandra Grochowska, Agnieszka Paziewska
Publikováno v:
Cancer Research. 79:1306-1306
Cyclin-dependent kinase 8 inhibitors (CDK8i) have anti-cancer activity in human acute myeloid leukaemia (AML) cell lines both in vitro and in vivo. Activity of CDK8i often involves deregulation of super-enhancer-associated genes in AML cell lines. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f9db6182a3417c8ab0d8a5f11fbb35
https://doi.org/10.1158/1538-7445.am2019-1306
https://doi.org/10.1158/1538-7445.am2019-1306
CDK8 Inhibitor SEL120-34A Has Therapeutic Efficacy in Murine and Human Acute Myeloid Leukemia Models
Autor:
Marion Chapellier, Marta Obacz, Ewelina Gabor-Worwa, Thoas Fioretos, Michal Combik, Arkadiusz Białas, Tomasz Rzymski, Carl Sandén, Katarzyna Wiklik, Elzbieta Fiedor, Marcus Järås, Eliza Majewska, Przemyslaw Juszczynski, Krzysztof Brzózka, Paulina Chesy, Anna Polak, Johan Flygare, Milena Mazan, Magdalena Masiejczyk, Jun Chen
Publikováno v:
Blood. 132:1520-1520
MJ and JF provided equal contribution as senior authors Acute myeloid leukemia (AML) is associated with poor survival and characterized by an accumulation of immature myeloid blasts in the bone marrow. To efficiently target AML, new therapies directe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c7768edc43dca3b525f03f563cc66a
https://doi.org/10.1182/blood-2018-99-111859
https://doi.org/10.1182/blood-2018-99-111859