Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Elzbieta Czarnecka"'
Autor:
Elzbieta Czarnecka, Bogusława Pietrzak
Publikováno v:
Pharmacological Reports. 62:278-286
Oxcarbazepine is a representative molecule for a new class of anticonvulsant drugs that can treat alcohol dependence in addition to other disorders. Interestingly, the central mechanism of action in oxcarbazepine is very similar to ethanol, suggestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d981f04b8197efb85950ed8c4d0a10
https://doi.org/10.1016/s1734-1140(10)70267-x
https://doi.org/10.1016/s1734-1140(10)70267-x
Publikováno v:
Neuroscience Letters. 431:221-225
Our previous studies have shown that repeated acamprosate administration to ethanol-naive Warsaw high preferring (WHP) rats resulted in increased plasma beta-endorphin levels and at least partially prevents increases in levels of this peptide after a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ba57bf9c326ab74f7389b5b58117cc
https://doi.org/10.1016/j.neulet.2007.11.041
https://doi.org/10.1016/j.neulet.2007.11.041
Autor:
Bogusława Pietrzak, Elzbieta Czarnecka
Publikováno v:
Basic Toxicology. 99:383-390
The central effect of ethanol is mainly connected with the effect on GABAergic, glutamatergic, serotonergic and opioid transmission. The mechanism of gabapentin effect suggests that it may alleviate the rewarding effect of ethanol, which may be used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b1dd5037a1b89899055b9620e28493
https://doi.org/10.1111/j.1742-7843.2006.pto_518.x
https://doi.org/10.1111/j.1742-7843.2006.pto_518.x
Publikováno v:
Pharmacology Biochemistry and Behavior. 85:155-159
An ample support can be found in professional literature for the hypothesis that the endogenous opioid system plays an important role in developing a craving for alcohol. It is well established that people with a genetic deficit of beta-endorphin are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625cde868d495aa50acd499cde0bc55b
https://doi.org/10.1016/j.pbb.2006.07.028
https://doi.org/10.1016/j.pbb.2006.07.028
Autor:
Elzbieta Czarnecka, Bogusława Pietrzak
Publikováno v:
Pharmacological Research. 47:527-534
In this study we have decided to examine acute interaction of ethanol with some drugs that belong to selective serotonin inhibitor (SSRI) group. Therefore, the influence of sertraline, fluoxetine and citalopram on the effect of ethanol on EEG of rabb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d091fcb210fbe2a9114cc8c13716092d
https://doi.org/10.1016/s1043-6618(03)00042-2
https://doi.org/10.1016/s1043-6618(03)00042-2
Autor:
Jan Epsztajn, Zbigniew Malinowski, Aleksandra K. Szcześniak, Dariusz Sroczyński, Elzbieta Czarnecka, Wanda Pakulska
A series of new alkyl, tosyl, acetyl, and tert-butoxycarbonyl derivatives of 2-(2-aminoethyl)-phthalazinones were efficiently synthesized by reaction of lactams with N-Boc-, N-acetyl-, or N,O-ditosyl derivatives of N-methylethanolamine in the presenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a0d253a6cf8daf7d19298d4e2a037c
Publikováno v:
Physiologybehavior. 102(5)
Many recent researches have confirmed the effectiveness of antiepileptic drugs in preventing alcohol dependency, whereas our previous study showed that repeated treatment with topiramate, a new antiepileptic drug, was effective in increasing the plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e2d0aa9ccdadec89f8e20ded3d8e3f
https://pubmed.ncbi.nlm.nih.gov/21187108
https://pubmed.ncbi.nlm.nih.gov/21187108
Autor:
Wanda, Pakulska, Elzbieta, Czarnecka
Publikováno v:
Acta poloniae pharmaceutica. 66(6)
Numerous methods of management applied in order to obtain higher therapeutic efficacy of drugs with minimum adverse effects include taking advantage of interactions taking place between individual agents. Analgesics are combined with drugs belonging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a9dfd9fa4c5ad2d2d8157ab473c35e7
https://pubmed.ncbi.nlm.nih.gov/20050537
https://pubmed.ncbi.nlm.nih.gov/20050537
Publikováno v:
Archiv der Pharmazie. 342(1)
New N-(dimethylamino)ethyl derivatives of phthalazinones and pyridopyridazinones 7, 9 were synthesized and assayed as potential analgesic agents in the hot-plate, tail-flick, and writhing tests. Pharmacological assay demonstrated that eight (in ten)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28875a892264aa66e113bf4a9897f82e
https://pubmed.ncbi.nlm.nih.gov/19051195
https://pubmed.ncbi.nlm.nih.gov/19051195
Publikováno v:
Physiologybehavior. 93(4-5)
It is well known that alcohol consumption leads to an increase in the levels of beta-endorphin (an endogenous opioid), which can contribute to the reinforcing effect of alcohol. Our previous studies have shown that repeated treatment with naltrexone,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a50ec69933a3094b7a0ff7885df1df
https://pubmed.ncbi.nlm.nih.gov/18262210
https://pubmed.ncbi.nlm.nih.gov/18262210