The Human Umbilical Cord Tissue-Derived MSC Population UCX Promotes Early Motogenic Effects on Keratinocytes and Fibroblasts and G-CSF-Mediated Mobilization of BM-MSCs when Transplanted In Vivo

Autor: Joana P. Miranda, Elysse Filipe, Ana Sofia Fernandes, Joana M. Almeida, José P. Martins, Alexandre De La Fuente, Miguel Abal, Rita N. Barcia, Pedro Cruz, Helder Cruz, Matilde Castro, Jorge M. Santos

Publikováno v: Cell Transplantation, Vol 24 (2015)

Mesenchymal stromal cells (MSCs) play an important role in tissue regeneration mainly through the secretion of trophic factors that enhance the repair of damaged tissues. The main goal of this work was to study the paracrine mechanisms by which an um

Externí odkaz: https://doaj.org/article/20be31655ad64fe4b8c28cb8071fadcd

Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing.

Autor: Santos, Jorge M¹ (AUTHOR), Camões, Sérgio P² (AUTHOR), Filipe, Elysse² (AUTHOR), Cipriano, Madalena² (AUTHOR), Barcia, Rita N¹ (AUTHOR), Filipe, Mariana¹ (AUTHOR), Teixeira, Mariana¹ (AUTHOR), Simões, Sandra² (AUTHOR), Gaspar, Manuela² (AUTHOR), Mosqueira, Diogo^3,4 (AUTHOR), Nascimento, Diana S^3,4 (AUTHOR), Pinto-do-Ó, Perpétua^3,4,5,6 (AUTHOR), Cruz, Pedro¹ (AUTHOR), Cruz, Helder¹ (AUTHOR), Castro, Matilde² (AUTHOR), Miranda, Joana P² (AUTHOR) jmiranda@ff.ulisboa.pt

Publikováno v: Stem Cell Research & Therapy. 2015, Vol. 6 Issue 1, p90-108. 19p. 1 Chart, 7 Graphs.