Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elyssa, Chen"'
Autor:
Nicole N. Scheff, Ian M. Wall, Sam Nicholson, Hannah Williams, Elyssa Chen, Nguyen H. Tu, John C. Dolan, Cheng Z. Liu, Malvin N. Janal, Nigel W. Bunnett, Brian L. Schmidt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Oral cancer patients report sensitivity to spicy foods and liquids. The mechanism responsible for chemosensitivity induced by oral cancer is not known. We simulate oral cancer-induced chemosensitivity in a xenograft oral cancer mouse model u
Externí odkaz:
https://doaj.org/article/18f2ffcae6f84a02abb412b9786e83d1
Autor:
Morley D. Hollenberg, Cheng Z. Liu, Elyssa Chen, Stephen Vanner, Dane D. Jensen, Nicole N. Scheff, Malvin N. Janal, Nigel W. Bunnett, Kenji Inoue, Hung D. Tran, Bethany M. Anderson, Nestor N. Jiménez-Vargas, Tamaryn A. Meek, Laura E. Edgington-Mitchell, Brian L. Schmidt, Nguyen Huu Tu, John C. Dolan
Publikováno v:
J Neurosci
Oral squamous cell carcinoma (OSCC) is one of the most painful cancers, which interferes with orofacial function including talking and eating. We report that legumain (Lgmn) cleaves protease-activated receptor-2 (PAR2) in the acidic OSCC microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb38e9c78774936a062a71497604525
https://doi.org/10.1523/jneurosci.1211-20.2020
https://doi.org/10.1523/jneurosci.1211-20.2020
Autor:
Nicole N, Scheff, Ian M, Wall, Sam, Nicholson, Hannah, Williams, Elyssa, Chen, Nguyen H, Tu, John C, Dolan, Cheng Z, Liu, Malvin N, Janal, Nigel W, Bunnett, Brian L, Schmidt
Publikováno v:
Scientific reports. 12(1)
Oral cancer patients report sensitivity to spicy foods and liquids. The mechanism responsible for chemosensitivity induced by oral cancer is not known. We simulate oral cancer-induced chemosensitivity in a xenograft oral cancer mouse model using two-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b13aca4a556a13d60bfd6e43bdd2bb2c
https://pubmed.ncbi.nlm.nih.gov/35260737
https://pubmed.ncbi.nlm.nih.gov/35260737
Autor:
Nguyen Huu, Tu, Kenji, Inoue, Elyssa, Chen, Bethany M, Anderson, Caroline M, Sawicki, Nicole N, Scheff, Hung D, Tran, Dong H, Kim, Robel G, Alemu, Lei, Yang, John C, Dolan, Cheng Z, Liu, Malvin N, Janal, Rocco, Latorre, Dane D, Jensen, Nigel W, Bunnett, Laura E, Edgington-Mitchell, Brian L, Schmidt
Publikováno v:
Cancers
Simple Summary Oral cancer is often deadly and severely painful. Because this form of cancer pain cannot be adequately treated with current medications including opiates, new treatment approaches are needed. Cathepsin S, a lysosomal cysteine protease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95e8caf08729ecdbe25cd1a0b0927901
https://pubmed.ncbi.nlm.nih.gov/34572924
https://pubmed.ncbi.nlm.nih.gov/34572924
Autor:
Kristy Conn, Thomas F. Floyd, John Petrie, Kennelia A Mellanson, Adriana DiBua, Betsy Cohen, Elyssa Chen, Michael Klingener, Joher Sheikh, Michael Cutrone, Cindy V. Leiton, Alissa Cutrone, Dania Malik, Ryan Lamm
Publikováno v:
Hypoxia
Cindy V Leiton,1,2 Elyssa Chen,2 Alissa Cutrone,3 Kristy Conn,2 Kennelia Mellanson,4 Dania M Malik,5 Michael Klingener,6 Ryan Lamm,7 Michael Cutrone,8 John Petrie IV,9 Joher Sheikh,10 Adriana DiBua,11 Betsy Cohen,12 Thomas F Floyd13–15 1Department
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ef10b3c3f6d63d02700ddc2e0a2e2a
https://doi.org/10.2147/hp.s173589
https://doi.org/10.2147/hp.s173589
Autor:
Rocco Latorre, John C. Dolan, Brian L. Schmidt, Caroline M. Sawicki, Dong H. Kim, Nicole N. Scheff, Kenji Inoue, Malvin N. Janal, Nigel W. Bunnett, Nguyen Huu Tu, Dane D. Jensen, Bethany M. Anderson, Lei Yang, Hung D. Tran, Laura E. Edgington-Mitchell, Elyssa Chen, Robel G. Alemu, Cheng Z. Liu
Publikováno v:
Cancers, Vol 13, Iss 4697, p 4697 (2021)
Cancers
Volume 13
Issue 18
Cancers
Volume 13
Issue 18
Oral squamous cell carcinoma (SCC) pain is more prevalent and severe than pain generated by any other form of cancer. We previously showed that protease-activated receptor-2 (PAR2) contributes to oral SCC pain. Cathepsin S is a lysosomal cysteine pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91069c6e298cea35db35f72c938b4698
https://doi.org/10.3390/cancers13184697
https://doi.org/10.3390/cancers13184697
Autor:
Holly R. Yeatman, Stuart M. Brierley, Dane D. Jensen, Peishen Zhao, Aditi Bhattacharya, Bernard L. Flynn, Nigel W. Bunnett, Christopher J.H. Porter, Rocco Latorre, Elyssa Chen, Daniel P. Poole, Laura E. Edgington-Mitchell, Luke A. Pattison, Peter McLean, Tina Marie Lieu, Michelle L. Halls, Nicholas A. Veldhuis, Nicole N. Scheff, Brian L. Schmidt, Giang Thanh Le, Gareth A. Hicks, Meritxell Canals, Stephen Vanner, Nestor N. Jiménez-Vargas, Luigi Aurelio, Joel Castro, Carmen Klein Herenbrink
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(31)
Once activated at the surface of cells, G protein-coupled receptors (GPCRs) redistribute to endosomes, where they can continue to signal. Whether GPCRs in endosomes generate signals that contribute to human disease is unknown. We evaluated endosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925e140445a29aa82dc5815de15e2429
https://pubmed.ncbi.nlm.nih.gov/30012612
https://pubmed.ncbi.nlm.nih.gov/30012612