Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elysia Roche"'
Autor:
Ernie Yulyaningsih, Jung H Suh, Melania Fanok, Roni Chau, Hilda Solanoy, Ryan Takahashi, Anna I Bakardjiev, Isabel Becerra, N Butch Benitez, Chi-Lu Chiu, Sonnet S Davis, William E Dowdle, Timothy Earr, Anthony A Estrada, Audrey Gill, Connie Ha, Patrick CG Haddick, Kirk R Henne, Martin Larhammar, Amy W-S Leung, Romeo Maciuca, Bahram Memarzadeh, Hoang N Nguyen, Alicia A Nugent, Maksim Osipov, Yingqing Ran, Kevin Rebadulla, Elysia Roche, Thomas Sandmann, Jing Wang, Joseph W Lewcock, Kimberly Scearce-Levie, Lesley A Kane, Pascal E Sanchez
Publikováno v:
eLife, Vol 12 (2024)
The integrated stress response (ISR) is a conserved pathway in eukaryotic cells that is activated in response to multiple sources of cellular stress. Although acute activation of this pathway restores cellular homeostasis, intense or prolonged ISR ac
Externí odkaz:
https://doaj.org/article/6521500dd1424027bebffc6920eba56b
Autor:
Kylie S. Chew, Robert C. Wells, Arash Moshkforoush, Darren Chan, Kendra J. Lechtenberg, Hai L. Tran, Johann Chow, Do Jin Kim, Yaneth Robles-Colmenares, Devendra B. Srivastava, Raymond K. Tong, Mabel Tong, Kaitlin Xa, Alexander Yang, Yinhan Zhou, Padma Akkapeddi, Lakshman Annamalai, Kaja Bajc, Marie Blanchette, Gerald Maxwell Cherf, Timothy K. Earr, Audrey Gill, David Huynh, David Joy, Kristen N. Knight, Diana Lac, Amy Wing-Sze Leung, Katrina W. Lexa, Nicholas P. D. Liau, Isabel Becerra, Mario Malfavon, Joseph McInnes, Hoang N. Nguyen, Edwin I. Lozano, Michelle E. Pizzo, Elysia Roche, Patricia Sacayon, Meredith E. K. Calvert, Richard Daneman, Mark S. Dennis, Joseph Duque, Kapil Gadkar, Joseph W. Lewcock, Cathal S. Mahon, René Meisner, Hilda Solanoy, Robert G. Thorne, Ryan J. Watts, Y. Joy Yu Zuchero, Mihalis S. Kariolis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Brain exposure of systemically administered biotherapeutics is highly restricted by the blood-brain barrier (BBB). Here, we report the engineering and characterization of a BBB transport vehicle targeting the CD98 heavy chain (CD98hc or SLC3
Externí odkaz:
https://doaj.org/article/c0dcaba8ffc04890ade94c8b75b21509
Autor:
Kylie S. Chew, Robert C. Wells, Arash Moshkforoush, Darren Chan, Kendra J. Lechtenberg, Hai L. Tran, Johann Chow, Do Jin Kim, Yaneth Robles-Colmenares, Devendra B. Srivastava, Raymond K. Tong, Mabel Tong, Kaitlin Xa, Alexander Yang, Yinhan Zhou, Padma Akkapeddi, Lakshman Annamalai, Kaja Bajc, Marie Blanchette, Gerald Maxwell Cherf, Timothy K. Earr, Audrey Gill, David Huynh, David Joy, Kristen N. Knight, Diana Lac, Amy Wing-Sze Leung, Katrina W. Lexa, Nicholas P. D. Liau, Isabel Becerra, Mario Malfavon, Joseph McInnes, Hoang N. Nguyen, Edwin I. Lozano, Michelle E. Pizzo, Elysia Roche, Patricia Sacayon, Meredith E. K. Calvert, Richard Daneman, Mark S. Dennis, Joseph Duque, Kapil Gadkar, Joseph W. Lewcock, Cathal S. Mahon, René Meisner, Hilda Solanoy, Robert G. Thorne, Ryan J. Watts, Y. Joy Yu Zuchero, Mihalis S. Kariolis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a16cb8fb950d46f9ab274a050ec42452
Autor:
Scarlett J Barker, Mai B Thayer, Chaeyoung Kim, David Tatarakis, Matthew Simon, Rebekah L Dial, Lizanne Nilewski, Robert C Wells, Yinhan Zhou, Megan Afetian, Alfred Chappell, Kylie S Chew, Johann Chow, Allisa Clemens, Claire B Discenza, Jason Dugas, Chrissa Dwyer, Timothy Earr, Connie Ha, David Huynh, Srini Jayaraman, Wanda Kwan, Cathal Mahon, Michelle Pizzo, Elysia Roche, Laura Sanders, Alexander Stergioulis, Raymond Tong, Hai Tran, Joy Zuchero, Anthony A Estrada, Kapil Gadkar, Christopher MM Koth, Pascal E Sanchez, Robert G Thorne, Ryan J Watts, Thomas Sandmann, Lesley Kane, Frank Rigo, Mark S Dennis, Joseph W Lewcock, Sarah L DeVos
Antisense oligonucleotides (ASO) are promising therapies for neurological disorders, though they are unable to cross the blood-brain barrier (BBB) and must be delivered directly to the central nervous system (CNS). Here, we use a human transferrin re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56046f97df89d6a2d15a721b2fca4f31
https://doi.org/10.1101/2023.04.25.538145
https://doi.org/10.1101/2023.04.25.538145
Autor:
Jose Ramon Quiros Garcia, Nela Pawlowska, Pamela N. Munster, Scott Thomas, Romain Pacaud, Elysia Roche, Mallika Sachdev Dhawan
Publikováno v:
Cancer Research. 80:P3-11
Background: BRCA1 and BRCA2 are key mediators of DNA damage repair response including the homologous recombination repair (HRR) pathway. Mutations in these genes predispose women to various cancers including breast, ovarian and pancreatic cancers. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d813f5b8263fd5d43f443ecd6196fd
https://doi.org/10.1158/1538-7445.sabcs19-p3-11-12
https://doi.org/10.1158/1538-7445.sabcs19-p3-11-12
Publikováno v:
J Am Assoc Lab Anim Sci
Fenbendazole is a broad-spectrum benzimidazole commonly used in laboratory animal medicine as an anthelmintic for elimination of pinworms. This drug is generally regarded as safe, with minimal side effects. Some data in rodent species indicate multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7631315b22335cbf9f20011197210d
https://pubmed.ncbi.nlm.nih.gov/34753534
https://pubmed.ncbi.nlm.nih.gov/34753534
Publikováno v:
Cancer Research. 79:P6-21
This abstract was not presented at the conference. Citation Format: Pacaud R, Thomas S, Roche E, Pawlowska N, Munster P. Not presented [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::505e6a5e6df47540a4050621d4cf854c
https://doi.org/10.1158/1538-7445.sabcs18-p6-21-10
https://doi.org/10.1158/1538-7445.sabcs18-p6-21-10