Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Elyse S. Fischer"'
Autor:
Elyse S. Fischer, Conny W. H. Yu, Johannes F. Hevler, Stephen H. McLaughlin, Sarah L. Maslen, Albert J. R. Heck, Stefan M. V. Freund, David Barford
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Formation of the mitotic checkpoint complex (MCC) is catalysed by a phosphorylation-dependent scaffold. This work provides structural details of how a tripartite Mad1:Bub1:Cdc20 complex presents Cdc20 to Mad2, triggering open-to-closed conversion of
Externí odkaz:
https://doaj.org/article/25af90ef4aa84deab038bcc19c9bacc5
Autor:
Stefan M.V. Freund, Conny Wing-Heng Yu, Elyse S Fischer, David Barford, Dom Bellini, Stephen H. McLaughlin, Armin Wagner, Christian M. Orr
Publikováno v:
EMBO Reports
During metaphase, in response to improper kinetochore‐microtubule attachments, the spindle assembly checkpoint (SAC) activates the mitotic checkpoint complex (MCC), an inhibitor of the anaphase‐promoting complex/cyclosome (APC/C). This process is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902e01a76cf600257a4b2251df2a1c87
