Toxicological Assessment of Flavor Ingredients in E-Vapor Products

Autor: Davide Sciuscio, Florian Calvino-Martin, Ashutosh Kumar, Timothy B. Langston, Elyette Martin, Diego Marescotti, Carole Mathis, Julia Hoeng, Manuel C. Peitsch, Donna C. Smith, Maria Gogova, Patrick Vanscheeuwijck, Kyeonghee M. Lee

Publikováno v: Frontiers in Toxicology, Vol 4 (2022)

Many flavor ingredients are often used in potentially reduced-risk tobacco products (such as e-vapor products). Although most are “generally recognized as safe (GRAS)” when used in food, there is limited information available on their long-term h

Externí odkaz: https://doaj.org/article/575444b99c4b40eba0477dc9cc873fcb

Comprehensive chemical characterization of the aerosol generated by a heated tobacco product by untargeted screening

Autor: Arno Knorr, Martin F. Almstetter, Serge Maeder, Mark Bentley, Elyette Martin, Daniel Arndt, Pavel Pospisil

Publikováno v: Analytical and Bioanalytical Chemistry

A suite of untargeted methods has been applied for the characterization of aerosol from the Tobacco Heating System 2.2 (THS2.2), a heated tobacco product developed by Philip Morris Products S.A. and commercialized under the brand name IQOS®. A total

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641dfec05cdc14a541e1476406b74cf6
https://pubmed.ncbi.nlm.nih.gov/32072212

Computer-Assisted Structure Identification (CASI)—An Automated Platform for High-Throughput Identification of Small Molecules by Two-Dimensional Gas Chromatography Coupled to Mass Spectrometry

Autor: André Stratmann, Elyette Martin, Markus Stueber, Arno Knorr, Pavel Pospisil, Aurelien Monge, Daniel Arndt

Publikováno v: Analytical Chemistry. 85:11216-11224

Compound identification is widely recognized as a major bottleneck for modern metabolomic approaches and high-throughput nontargeted characterization of complex matrices. To tackle this challenge, an automated platform entitled computer-assisted stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3575a1e41410707536abc8abdd4756b9
https://doi.org/10.1021/ac4011952

Mechanisms of propylene glycol and triacetin pyrolysis

Autor: Christian Tuma, Elyette Martin, Alessandro Curioni, Steffen Stolz, Teodoro Laino, Philippe Moor

Publikováno v: Journal of physical chemistry A, 116(18), 4602-4609. American Chemical Society

Propylene glycol and triacetin are chemical compounds, commonly used as food additives. Though the usage of the pure chemicals is not considered harmful when used as dietary supplements, little is known about the nature of their thermal degradation p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d659a43a0e6e76a01498b86943b4fd
https://doi.org/10.1021/jp300997d

Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor

Autor: Jean-Marie Wurtz, Elyette Martin, Caroline Loch, Dino Moras, Roland H. Stote, Christopher Browning, Annick Dejaegere, Isabelle M. L. Billas

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (45), pp.32924-32934. ⟨10.1074/jbc.M705559200⟩

The insect steroid hormone 20-hydroxyecdysone (20E) binds to its cognate nuclear receptor composed of the ecdysone receptor (EcR) and Ultraspiracle (USP) and triggers the main developmental transitions, in particular molting and metamorphosis. We pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1db4f3418ea3b70c6c4ca9f317a2769
https://doi.org/10.1074/jbc.m705559200