Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ely, Cosino"'
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
XLS file - 22K, Significance and frequency of KRAS amplification across multiple cancer types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb5290ebb5488f8e825753516a4c195
https://doi.org/10.1158/1078-0432.22448457
https://doi.org/10.1158/1078-0432.22448457
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
Purpose: This study is aimed to identify genes within the KRAS genomic amplicon that are both coupregulated and essential for cell proliferation when KRAS is amplified in lung cancer.Experimental Design: We used an integrated genomic approach to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21add0973b931e45711f893e0e29032b
https://doi.org/10.1158/1078-0432.c.6521406
https://doi.org/10.1158/1078-0432.c.6521406
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
PDF file - 150K, LDHB expression correlates with poor overall survival in lung tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0f69724311dcb5bc48af78f67fd7d5
https://doi.org/10.1158/1078-0432.22448463.v1
https://doi.org/10.1158/1078-0432.22448463.v1
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
PDF file - 138K, LDHB expression analysis in KRAS mutant cancers versus wildtype colon cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e66dcf5d65083882bf3c03a56c6d76c
https://doi.org/10.1158/1078-0432.22448472.v1
https://doi.org/10.1158/1078-0432.22448472.v1
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
PDF file - 110K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e586c7f958b856639c97ec09d5b00e
https://doi.org/10.1158/1078-0432.22448460
https://doi.org/10.1158/1078-0432.22448460
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
XLS file - 12K, KRAS mutation status and copy number of KRAS and LDHB in NSCLC cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006e7102ab141decc8c9971c55e6efd8
https://doi.org/10.1158/1078-0432.22448451.v1
https://doi.org/10.1158/1078-0432.22448451.v1
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
PDF file - 214K, LDHB expression and dependence in lung adenocarcinoma cell lines containing various oncogenic drivers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e976df3798e36cb52cb790e2b84b199
https://doi.org/10.1158/1078-0432.22448466.v1
https://doi.org/10.1158/1078-0432.22448466.v1
Autor:
Ron Firestein, William F. Forrest, Erica Jackson, David Shames, Li Li, Janet Tao, Margaret Solon, Elizabeth M. Blackwood, Leslie Lee, Ely Cosino, Laura Deming, Adam S. Adler, Mark L. McCleland
PDF file - 160K, RNAi of KRAS to determine cellular dependence on proliferation and effects on LDHB expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06474047697ae48c64bdb3f196e6f2c7
https://doi.org/10.1158/1078-0432.22448469.v1
https://doi.org/10.1158/1078-0432.22448469.v1
Autor:
Thomas O'Brien, Jason Oeh, Yang Xiao, Xiaorong Liang, Alexander Vanderbilt, Ann Qin, Lulu Yang, Leslie B. Lee, Justin Ly, Ely Cosino, Jennifer A. LaCap, Annie Ogasawara, Simon Williams, Michelle Nannini, Bianca M. Liederer, Peter Jackson, Peter S. Dragovich, Deepak Sampath
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 12, Pp 1314-1329 (2013)
Nicotinamide adenine dinucleotide (NAD) is a metabolite essential for cell survival and generated de novo from tryptophan or recycled from nicotinamide (NAM) through the nicotinamide phosphoribosyltransferase (NAMPT)-dependent salvage pathway. Altern
Externí odkaz:
https://doaj.org/article/8535a58d3d9848dc8bfb8adf33b8bae4
Autor:
Jianhui Zhou, Jintang He, Breanna S. Vollmar, Shang-Fan Yu, Hans Erickson, Sharon Yee, Greg A. Lazar, Binqing Wei, Aimee Fourie-O'Donohue, Genee Lee, Amrita V. Kamath, Douglas D. Leipold, Rachana Ohri, Guangmin Li, Gail Lewis Phillips, Ely Cosino, Keyang Xu, Katherine R. Kozak
Publikováno v:
Bioconjugate Chemistry. 28:2538-2548
The incorporation of cysteines into antibodies by mutagenesis allows for the direct conjugation of small molecules to specific sites on the antibody via disulfide bonds. The stability of the disulfide bond linkage between the small molecule and the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a2136e028db58ed736a2814624d0b95
https://doi.org/10.1021/acs.bioconjchem.7b00365
https://doi.org/10.1021/acs.bioconjchem.7b00365