Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Elwyn, Welch"'
Autor:
Deepak Tripathi, Sambasivan Venkatasubramanian, Satyanarayana S. Cheekatla, Padmaja Paidipally, Elwyn Welch, Amy R. Tvinnereim, Ramakrishna Vankayalapati
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Tolerance is required to prevent rejection of intrahepatic islet allografts as a potential treatment for type 1 diabetes. Here the authors show that IL-22 produced by NK1.1+cells in the liver of streptozotocin T1D model mice can drive tolerance to al
Externí odkaz:
https://doaj.org/article/0f70979a3a894b3e92593ad42eeb98f0
Publikováno v:
Drugs
Urinary tract infections, including cystitis, acute pyelonephritis, and prostatitis, are among the most common diagnoses prompting antibiotic prescribing. The rise in antimicrobial resistance over the past decades has led to the increasing challenge
Autor:
Deepak Tripathi, Elwyn Welch, Satyanarayana Swamy Cheekatla, Rajesh Kumar Radhakrishnan, Sambasivan Venkatasubramanian, Padmaja Paidipally, Abhinav Van, Buka Samten, Kamakshi P Devalraju, Venkata Sanjeev Kumar Neela, Vijaya Lakshmi Valluri, Carol Mason, Steve Nelson, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007174 (2018)
In the current study, we used a mouse model and human blood samples to determine the effects of chronic alcohol consumption on immune responses during Mycobacterium tuberculosis (Mtb) infection. Alcohol increased the mortality of young mice but not o
Externí odkaz:
https://doaj.org/article/a165f4be7a73421798514df756d6ec4f
Autor:
Uma, Ayyala, Shazia, Raheem, Jefferson L, Triozzi, Andrew, Hunter, Elwyn, Welch, Stephen, Bujarski, Christina, Kao, Lavannya, Pandit, Kanta, Velamuri, Venkata D, Bandi
Publikováno v:
Fed Pract
BACKGROUND: During a surge of COVID-19 cases, the volume of acute care patients with hypoxemic respiratory failure placed a high burden of responsibility on internal medicine, pulmonary and critical care medicine, and clinical pharmacy services. OBSE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10aef330969788b82febb52ad096d1e
https://europepmc.org/articles/PMC9652024/
https://europepmc.org/articles/PMC9652024/
Autor:
Satyanarayana Swamy Cheekatla, Deepak Tripathi, Sambasivan Venkatasubramanian, Pavan Kumar Nathella, Padmaja Paidipally, Munenori Ishibashi, Elwyn Welch, Amy R Tvinnereim, Mitsuo Ikebe, Vijaya Lakshmi Valluri, Subash Babu, Hardy Kornfeld, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005972 (2016)
In this study, we developed a mouse model of type 2 diabetes mellitus (T2DM) using streptozotocin and nicotinamide and identified factors that increase susceptibility of T2DM mice to infection by Mycobacterium tuberculosis (Mtb). All Mtb-infected T2D
Externí odkaz:
https://doaj.org/article/1632fad0303f48a0a4efb8a496c08bf3
Autor:
Sambasivan Venkatasubramanian, Rohan Dhiman, Padmaja Paidipally, Satyanarayana S Cheekatla, Deepak Tripathi, Elwyn Welch, Amy R Tvinnereim, Brenda Jones, Dan Theodorescu, Peter F Barnes, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004617 (2015)
In this study, we found that a subpopulation of CD4(+)CD25(+) (85% Foxp3(+)) cells from persons with latent tuberculosis infection (LTBI) inhibits growth of M. tuberculosis (M. tb) in human monocyte-derived macrophages (MDMs). A soluble factor, Rho G
Externí odkaz:
https://doaj.org/article/491a31ef392946ccaf136ad97d06270b
Publikováno v:
Open Forum Infect Dis
Background The emergence of antimicrobial resistance in uropathogens has generated interest in the use of nitrofurantoin in controversial populations, such as in males and those with renal dysfunction. The purpose of this study was to compare the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995f836e00df2ae4511095410ef202f0
https://europepmc.org/articles/PMC8454520/
https://europepmc.org/articles/PMC8454520/
Autor:
Elwyn Welch, Shazia Raheem, Andrew Hunter, Uma Ayyala, Venkata Bandi, Lavannya Pandit, Christina Kao
Publikováno v:
Open Forum Infectious Diseases
Background Patient and treatment-related factors have been used to stratify COVID-19 outcomes; however, studies in the general population and specifically veterans have yielded variable results. This study was designed to assess how baseline characte
Autor:
Ramakrishna Vankayalapati, Satyanarayana S. Cheekatla, Amy R. Tvinnereim, Rajesh Kumar Radhakrishnan, Ramya Sivangala Thandi, Padmaja Paidipally, Deepak Tripathi, Elwyn Welch
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
CD4+CD25+FoxP3+ cells (Tregs) inhibit inflammatory immune responses to allografts. Here, we found that co-transplantation of allogeneic pancreatic islets with Tregs that are defective in c-Jun N-terminal kinase 1 (JNK1) signaling prolongs islet allog
Autor:
Padmaja Paidipally, Roza Nurieva, Deepak Tripathi, Sambasivan Venkatasubramanian, Amy R. Tvinnereim, Ramakrishna Vankayalapati, Elwyn Welch, Satyanarayana Swamy Cheekatla
Publikováno v:
The Journal of Immunology. 199:2815-2822
In this study, we determined the role of IL-21R signaling in Mycobacterium tuberculosis infection, using IL-21R knockout (KO) mice. A total of 50% of M. tuberculosis H37Rv–infected IL-21R KO mice died in 6 mo compared with no deaths in infected wil