Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elvis M. K. Leung"'
Autor:
Gary N. W. Leung, Terence S.M. Wan, Farrington F. Adrian, Karen Y. Kwok, Ming Yip Lau, Timmy L.S. Choi, Elvis M. K. Leung, Wai Him Kwok, Anil Prabhu, Emmie N.M. Ho, Jenny K.Y. Wong
Publikováno v:
Drug testing and analysisREFERENCES. 12(9)
The use of bioactive peptides as a doping agent in both human and animal sports has become increasingly popular in recent years. As such, methods to control the misuse of bioactive peptides in equine sports have received attention. This paper describ
Publikováno v:
Analytical and Bioanalytical Chemistry. 408:953-961
The commonly used method of analyzing carcinogen-induced DNA adducts involves the hydrolysis of carcinogen-modified DNA samples by using a mixture of enzymes, followed by (32)P-postlabeling or liquid chromatography (LC)-based analyses of carcinogen-m
Publikováno v:
Journal of Agricultural and Food Chemistry. 63:3161-3167
Carcinogenic nitropolycyclic aromatic hydrocarbons (nitro-PAHs) are ubiquitous in the ambient environment. They are emitted predominantly from internal combustion engines and by reacting polycyclic aromatic hydrocarbons with nitrogen oxide. The emerg
Autor:
Elvis M. K. Leung, Wan Chan
Publikováno v:
Chemical Research in Toxicology. 28:248-255
Prolonged exposure to aristolochic acid (AA)contaminated slimming drugs and food is believed to be associated with the development of endemic nephropathy in Belgian women and in farmers living alongside the Danube River. Decades of research has revea
Autor:
Wan Chan, Elvis M. K. Leung
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. :1-6
Nephrotoxic aristolochic acids (AAs) form covalently bonded DNA adducts upon metabolic activation. In this work, a non-invasive approach to detect AAs exposure by quantifying urinary excreted DNA-AA adducts is presented. The developed method entails
Autor:
Wan Chan, Elvis M. K. Leung
Publikováno v:
Chemical Research in Toxicology. 28:567-569
Balkan endemic nephropathy (BEN) is a peculiar renal disease affecting thousands of farmers living in the suburban areas of the Balkan countries. Emerging evidence suggested that BEN is an environmental disease caused by chronic food poisoning with a
Publikováno v:
Journal of Agricultural and Food Chemistry. 61:9950-9954
2-Alkylcyclobutanones (2-ACBs) have long been considered as unique radiolytic products that can be used as indicators for irradiated food identification. A recent report on the natural existence of 2-ACB in non-irradiated nutmeg and cashew nut sample
Publikováno v:
Analytical and Bioanalytical Chemistry. 405:4059-4066
Apurinic/apyrimidinic (AP) sites are common DNA lesions arising from spontaneous hydrolysis of the N-glycosidic bond and base-excision repair mechanisms of the modified bases. Due to the strong association of AP site formation with physically/chemica
Autor:
Elvis M. K. Leung, Wan Chan
Publikováno v:
Analytical and bioanalytical chemistry. 406(6)
Creatinine is an important biomarker for renal function diagnosis and normalizing variations in urinary drug/metabolites concentration. Quantification of creatinine in biological fluids such as urine and plasma is important for clinical diagnosis as
Publikováno v:
Food chemistry. 161
2-Dodecylcyclobutanone (2-DCB) is one of the major 2-alkylcyclobutanones (2-ACBs) that are uniquely formed when triglycerides are exposed to ionizing radiation and is being widely used as marker signature for identifying irradiated food. Current meth