Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Elvis Cuevas"'
Autor:
Zahra Kolahchi, Nicholas Henkel, Mahmoud A. Eladawi, Emma C. Villarreal, Prathik Kandimalla, Anna Lundh, Robert E. McCullumsmith, Elvis Cuevas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8485 (2024)
Two-thirds of Americans with Alzheimer’s disease are women, indicating a profound variance between the sexes. Variances exist between the sexes in the age and intensity of the presentation, cognitive deficits, neuroinflammatory factors, structural
Externí odkaz:
https://doaj.org/article/6d9ce41528ad4425807c39755f7262c0
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 806-813 (2022)
The pathophysiology underlying the loss of dopaminergic neurons in Parkinson’s disease (PD) is unclear. A gap of knowledge in the molecular and cellular events leading to degeneration of the nigrostriatal DA system is a major barrier to the develop
Externí odkaz:
https://doaj.org/article/659cd74f08e64897b54d3a68fe7918d1
Autor:
Iris N Serratos, Pilar Castellanos, Nina Pastor, César Millán-Pacheco, Daniel Rembao, Ruy Pérez-Montfort, Nallely Cabrera, Francisco Reyes-Espinosa, Paulina Díaz-Garrido, Ambar López-Macay, Karina Martínez-Flores, Alberto López-Reyes, Aurora Sánchez-García, Elvis Cuevas, Abel Santamaria
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120221 (2015)
The receptor for advanced glycation end products (RAGE) is a pattern-recognition receptor involved in neurodegenerative and inflammatory disorders. RAGE induces cellular signaling upon binding to a variety of ligands. Evidence suggests that RAGE up-r
Externí odkaz:
https://doaj.org/article/c2c05799de3241249d12296d41def1f5
Autor:
Syed Jafar Mehdi, Hector Rosas-Hernandez, Elvis Cuevas, Susan M. Lantz, Steven W. Barger, Sumit Sarkar, Merle G. Paule, Syed F. Ali, Syed Z. Imam
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 9, p 1585 (2016)
Currently, the lack of new drug candidates for the treatment of major neurological disorders such as Parkinson’s disease has intensified the search for drugs that can be repurposed or repositioned for such treatment. Typically, the search focuses o
Externí odkaz:
https://doaj.org/article/abcda3fa228b4d7ba7c44f1aa5a6fd6d
Autor:
Paola Flores-Rodríguez, B. Berenice Campa-Córdoba, Marely Bravo-Muñoz, Miguel Ángel Ontiveros-Torres, Mar Pacheco-Herrero, Luis O Soto-Rojas, Linda Garcés-Ramírez, Ricardo Apátiga-Pérez, Nabil Itzi Luna-Viramontes, José Francisco Montiel-Sosa, Ignacio Villanueva-Fierro, José Luna-Muñoz, Elvis Cuevas, Fidel de la Cruz
Publikováno v:
Metabolic Brain Disease. 37:39-50
Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive functions and short-term memory. AD patients present two distinctive neuropathological lesions: neuritic plaques and neurofibrillary tangles (NFTs), constituted o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d78d5fcb6357768f36d26c021cd075d
https://doi.org/10.1007/s11011-021-00814-4
https://doi.org/10.1007/s11011-021-00814-4
Publikováno v:
Brain, Behavior, and Immunity
Highlights • SARS-CoV-2 may infect immature olfactory sense neurons. • Olfactory sense neurons and the blood brain barrier may allow infection of the brain. • The distribution of ACE2, or novel cellular entry proteins, will limit viral spread.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb792344c19d18dd9c2ec3e6bcfce78
https://doi.org/10.1016/j.bbi.2020.12.031
https://doi.org/10.1016/j.bbi.2020.12.031
Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
Autor:
Sumit Sarkar, Aida G Guzman Lopez, Srinivasulu Chigurupati, Susan M. Burks, Nancy P. Gomez-Crisostomo, Bonnie L. Robinson, Claudia Escudero-Lourdes, Joseph P. Hanig, James Raymick, Sherry A. Ferguson, Elvis Cuevas
Publikováno v:
Nutritional Neuroscience. 25:1374-1391
Parkinson's disease (PD) is a progressive motor disease of unknown etiology. Although neuroprotective ability of endogenous bile acid, tauroursodeoxycholic acid (TUDCA), shown in various diseases, including an acute model of PD,the potential therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ab5afca9a8cf853e4a911968939049
https://doi.org/10.1080/1028415x.2020.1859729
https://doi.org/10.1080/1028415x.2020.1859729
Publikováno v:
Neuroscience. 440:48-55
Alzheimer's disease (AD) pathology is characterized by amyloid plaques containing amyloid beta (Aβ) peptides, neurofibrillary tangles containing hyperphosphorylated tau protein, and neuronal loss. In addition, Aβ deposition in brain microvessels, k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e901ee10a37c5a7084e71435e96be22
https://doi.org/10.1016/j.neuroscience.2020.05.024
https://doi.org/10.1016/j.neuroscience.2020.05.024
Publikováno v:
Molecular Neurobiology. 57:32-40
One of the most abundant proteins expressed in the brain, 14-3-3 comprises about 1% of the brain's total soluble proteins. The 14-3-3 isoforms bind to specific phosphoserine- and phosphothreonine-containing motifs found on a variety of signaling prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44a0c73ff4c1939d270e4e5e5c42988
https://doi.org/10.1007/s12035-019-01754-y
https://doi.org/10.1007/s12035-019-01754-y
Autor:
Elvis Cuevas, Susan M. Burks, Sumit Sarkar, Syed F. Ali, Hector Rosas-Hernandez, Aida Guzman, Syed Z. Imam, Manuel A. Ramirez-Lee
Publikováno v:
Metabolic Brain Disease. 34:1365-1374
The amyloid β-peptide (Aβ) is transported across the blood-brain barrier (BBB) by binding with the receptor for advanced glycation end products (RAGE). Previously, we demonstrated that the Aβ fraction 25–35 (Aβ25–35) increases RAGE expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7296c378aa8fd2fcd873e14d41dfe538
https://doi.org/10.1007/s11011-019-00447-8
https://doi.org/10.1007/s11011-019-00447-8